Results 31 to 40 of about 28,936 (237)
Background and Objectives: Diphtheria is a potentially fatal disease caused by toxigenic bacterial infection, particularly from Corynebacterium diphtheriae (C. diphtheriae). Isolation of C.
Yeva Rosana+4 more
doaj +1 more source
Diphtheria toxin is a single-chain protein toxin that invades human cells by receptor-mediated endocytosis. In acidic endosomes, its translocation domain inserts into endosomal membranes and facilitates the transport of the catalytic domain (DTA) from ...
Leonie Schnell+5 more
doaj +1 more source
Background Infections caused by Corynebacterium ulcerans, a zoonotic pathogen, have been reported worldwide. This microorganism is known to produce the diphtheria toxin and cause diphtheria‐like illness.
Koji Wake+10 more
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The Aftermath of Flood Crises- Diphtheria Outbreak in Sindh [PDF]
The recent floods in Pakistan have not only resulted in greater than 1290 deaths and 12500 flood-related injuries but also thousands of cases of communicable and non-communicable diseases [1].
Syed Bilal Hashmi, Laraib Malik
doaj +1 more source
The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells
Diphtheria toxin kills human cells because it delivers its enzyme domain DTA into their cytosol where it inhibits protein synthesis. After receptor-mediated uptake of the toxin, DTA translocates from acidic endosomes into the cytosol, which might be ...
Manuel Schuster+16 more
doaj +1 more source
Contribution to study of diphtheria toxin [PDF]
The results reported are those of experiments planned to throw further light on the mechanism of toxin production by B.
Moloney, P. J., Hanna, L.
openaire +3 more sources
CsrA and its regulators control the time-point of ColicinE2 release in Escherichia coli [PDF]
The bacterial SOS response is a cellular reaction to DNA damage, that, among other actions, triggers the expression of colicin - toxic bacteriocins in Escherichia coli that are released to kill close relatives competing for resources. However, it is largely unknown, how the complex network regulating toxin expression controls the time-point of toxin ...
arxiv +1 more source
Environmental toxicity influences disease spread in consumer population [PDF]
The study of infectious disease has been of interest to ecologists since long. The initiation of epidemic and the long term disease dynamics are largely influenced by the nature of the underlying consumer (host)-resource dynamics. Ecological traits of such systems may be often modulated by toxins released in the environment due to ongoing anthropogenic
arxiv
Modeling sRNA-regulated Plasmid Maintenance [PDF]
We study a theoretical model for the toxin-antitoxin (hok/sok) mechanism for plasmid maintenance in bacteria. Toxin-antitoxin systems enforce the maintenance of a plasmid through post-segregational killing of cells that have lost the plasmid. Key to their function is the tight regulation of expression of a protein toxin by an sRNA antitoxin.
arxiv +1 more source
Chemical warfare and survival strategies in bacterial range expansions [PDF]
Dispersal of species is a fundamental ecological process in the evolution and maintenance of biodiversity. Limited control over ecological parameters has hindered progress in understanding of what enables species to colonise new area, as well as the importance of inter-species interactions.
arxiv +1 more source