Results 31 to 40 of about 28,936 (237)

Detection of toxin-producing Corynebacterium diphtheriae from throat swabs of diphtheria patients using duplex real-time PCR

open access: yesIranian Journal of Microbiology, 2020
Background and Objectives: Diphtheria is a potentially fatal disease caused by toxigenic bacterial infection, particularly from Corynebacterium diphtheriae (C. diphtheriae). Isolation of C.
Yeva Rosana   +4 more
doaj   +1 more source

Semicarbazone EGA Inhibits Uptake of Diphtheria Toxin into Human Cells and Protects Cells from Intoxication

open access: yesToxins, 2016
Diphtheria toxin is a single-chain protein toxin that invades human cells by receptor-mediated endocytosis. In acidic endosomes, its translocation domain inserts into endosomal membranes and facilitates the transport of the catalytic domain (DTA) from ...
Leonie Schnell   +5 more
doaj   +1 more source

Transmission of toxigenic Corynebacterium ulcerans infection with airway obstruction from cats to a human

open access: yesAcute Medicine & Surgery, 2021
Background Infections caused by Corynebacterium ulcerans, a zoonotic pathogen, have been reported worldwide. This microorganism is known to produce the diphtheria toxin and cause diphtheria‐like illness.
Koji Wake   +10 more
doaj   +1 more source

The Aftermath of Flood Crises- Diphtheria Outbreak in Sindh [PDF]

open access: yesLiaquat National Journal of Primary Care, 2023
The recent floods in Pakistan have not only resulted in greater than 1290 deaths and 12500 flood-related injuries but also thousands of cases of communicable and non-communicable diseases [1].
Syed Bilal Hashmi, Laraib Malik
doaj   +1 more source

The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells

open access: yesScientific Reports, 2017
Diphtheria toxin kills human cells because it delivers its enzyme domain DTA into their cytosol where it inhibits protein synthesis. After receptor-mediated uptake of the toxin, DTA translocates from acidic endosomes into the cytosol, which might be ...
Manuel Schuster   +16 more
doaj   +1 more source

Contribution to study of diphtheria toxin [PDF]

open access: yesExperimental Biology and Medicine, 1921
The results reported are those of experiments planned to throw further light on the mechanism of toxin production by B.
Moloney, P. J., Hanna, L.
openaire   +3 more sources

CsrA and its regulators control the time-point of ColicinE2 release in Escherichia coli [PDF]

open access: yesScientific Reports 8, 6537 (2018), 2018
The bacterial SOS response is a cellular reaction to DNA damage, that, among other actions, triggers the expression of colicin - toxic bacteriocins in Escherichia coli that are released to kill close relatives competing for resources. However, it is largely unknown, how the complex network regulating toxin expression controls the time-point of toxin ...
arxiv   +1 more source

Environmental toxicity influences disease spread in consumer population [PDF]

open access: yesarXiv, 2022
The study of infectious disease has been of interest to ecologists since long. The initiation of epidemic and the long term disease dynamics are largely influenced by the nature of the underlying consumer (host)-resource dynamics. Ecological traits of such systems may be often modulated by toxins released in the environment due to ongoing anthropogenic
arxiv  

Modeling sRNA-regulated Plasmid Maintenance [PDF]

open access: yes, 2016
We study a theoretical model for the toxin-antitoxin (hok/sok) mechanism for plasmid maintenance in bacteria. Toxin-antitoxin systems enforce the maintenance of a plasmid through post-segregational killing of cells that have lost the plasmid. Key to their function is the tight regulation of expression of a protein toxin by an sRNA antitoxin.
arxiv   +1 more source

Chemical warfare and survival strategies in bacterial range expansions [PDF]

open access: yesJ. R. Soc. Interface 11, 20140172 (2014), 2014
Dispersal of species is a fundamental ecological process in the evolution and maintenance of biodiversity. Limited control over ecological parameters has hindered progress in understanding of what enables species to colonise new area, as well as the importance of inter-species interactions.
arxiv   +1 more source

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