Results 31 to 40 of about 362,065 (266)
METHODS OF CONTROL DIPHTHERIA VACCINE SAFETY [PDF]
Annals of Mechnikov's Institute, 2016 Vaccination success depends not only on the timely coverage of threatened contingents, but also on the quality of vaccines. Every day, the requirements for security guarantees vaccines and their use guarantees of security increases.
Isayenko Ye. Yu +5 more
doaj +1 more source
Diphtheria: A case series from West Maharashtra, India
Journal of Medical Sciences and Health, 2022 Diphtheria is an acute infectious toxin mediated disease caused by Corynebacterium diphtheriae. Effective vaccination has decreased the incidence of disease globally. However, despite of a full-fledged Universal Immunization Programme, the cases
Snehal Patil +3 more
doaj +1 more source
Clinical Infectious Diseases, 2020 Respiratory illness caused by Corynebacterium diphtheriae and C. ulcerans, and use of diphtheria anti-toxin in the United States, 1996-2018. BACKGROUND Respiratory diphtheria is a toxin-mediated disease caused by Corynebacterium diphtheriae. Diphtheria-
John O. Otshudiema +5 more
semanticscholar +1 more source
Diphtheritic myocarditis: A case series and review of literature
Journal of Family Medicine and Primary Care, 2020 Myocarditis in patients with diphtheria is a toxin-mediated complication that sets in after one week of onset of respiratory illness. Early administration of antidiphtheritic serum in patients with clinical diphtheria before the onset of myocarditis is ...
Sonali Singh, Nitin Gupta, Pallavi Saple
doaj +1 more source
Genetic characterization of diphtheria tox B to evaluate vaccine efficacy in Indonesia
Iranian Journal of Microbiology, 2022 Background and Objectives: Blocking the attachment of diphtheria toxins to host cells through the intact receptor binding site (tox B) was the initial mechanism of action of the diphtheria vaccine.
Yeva Rosana +2 more
doaj +1 more source
Clinical Case Studies and Reports, 2019 Diphtheria toxin is an exotoxin secreted by Corynebacterium diphtheriae, the pathogenic bacterium that causes diphtheria. Unusually, the toxin gene is encoded by a bacteriophage (a virus that infects bacteria).
A. Heidari +2 more
semanticscholar +1 more source
Microbiology spectrum, 2019 Diphtheria is one of the most well studied of all the bacterial infectious diseases. These milestone studies of toxigenic Corynebacterium diphtheriae along with its primary virulence determinant, diphtheria toxin, have established the paradigm for the ...
S. Parveen, W. Bishai, J. Murphy
semanticscholar +1 more source
Angewandte Chemie, EarlyView.The self‐adjuvanting vaccine—comprising a covalent conjugate of antigen and adjuvant—was formulated into cationic lipid nanoparticles smaller than 100 nm to facilitate uptake by immune cells, with supplemental adjuvants incorporated to modulate immune responses.
Keita Ito +9 more
wiley +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Regulatory T cells (Tregs) infiltrate tumors in various cancers and promote an immunosuppressive microenvironment that hinders antitumor immunity. Denileukin diftitox, a diphtheria-toxin–based fusion protein that depletes Tregs, was approved
Laurene S Cheung +12 more
semanticscholar +1 more source
Population genomics and antimicrobial resistance in Corynebacterium diphtheriae
Genome Medicine, 2020 Background Corynebacterium diphtheriae, the agent of diphtheria, is a genetically diverse bacterial species. Although antimicrobial resistance has emerged against several drugs including first-line penicillin, the genomic determinants and population ...
Melanie Hennart +12 more
doaj +1 more source