Results 61 to 70 of about 358,147 (271)

On the Toxin Production of the Diphtheria Bacillus [PDF]

open access: yesEpidemiology and Infection, 1912
Everyone who has been occupied with the weekly production of diphtheria toxin in quantity has been struck with the great variations which may and usually do occur in the strength of the toxin from week to week. It is indeed extraordinary as Madsen remarks (1908, p.
openaire   +3 more sources

Contribution to study of diphtheria toxin [PDF]

open access: yesExperimental Biology and Medicine, 1921
The results reported are those of experiments planned to throw further light on the mechanism of toxin production by B.
Moloney, P. J., Hanna, L.
openaire   +2 more sources

pH-Triggered Conformational Switching along the Membrane Insertion Pathway of the Diphtheria Toxin T-Domain

open access: yesToxins, 2013
The translocation (T)-domain plays a key role in the action of diphtheria toxin and is responsible for transferring the catalytic domain across the endosomal membrane into the cytosol in response to acidification.
A. Ladokhin
semanticscholar   +1 more source

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

open access: yesAdvanced NanoBiomed Research, EarlyView.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez   +3 more
wiley   +1 more source

Sequence Analysis of Toxin Gene–Bearing Corynebacterium diphtheriae Strains, Australia

open access: yesEmerging Infectious Diseases, 2017
By conducting a molecular characterization of Corynebacterium diphtheriae strains in Australia, we identified novel sequences, nonfunctional toxin genes, and 5 recent cases of toxigenic cutaneous diphtheria.
Christine J. Doyle   +5 more
doaj   +1 more source

ADP-ribosylation of Translation Elongation Factor 2 by Diphtheria Toxin in Yeast Inhibits Translation and Cell Separation*

open access: yesJournal of Biological Chemistry, 2013
Background: Diphtheria toxin inhibits translation by ADP-ribosylation of elongation factor 2. Results: Diphtheria toxin expression results in accumulation of cells that fail to separate following mitosis.
M. Mateyak, T. Kinzy
semanticscholar   +1 more source

Development and Validation of a High‐Throughput Screening Assay for the Legionella ADP‐Ribosyl Transferase SdeA

open access: yesChemBioChem, EarlyView.
We show the optimization and application of a fluorogenic assay to monitor Legionella SdeA activity in a High‐Throughput‐Screening campaign. Ubiquitination of proteins is one of the most crucial post‐translational modifications in eukaryotic cells, typically involving conjugation of ubiquitin to a lysine residue in a substrate using a three‐enzyme ...
Halana C. Vlaming   +6 more
wiley   +1 more source

Diphtheria Antitoxin Levels in the Netherlands: a Population-Based Study

open access: yesEmerging Infectious Diseases, 1999
In a population-based study in the Netherlands, diphtheria antitoxin antibodies were measured with a toxin-binding inhibition assay in 9,134 sera from the general population and religious communities refusing vaccination.
Hester E. de Melker   +3 more
doaj   +1 more source

Diphtheria toxin: nucleotide binding and toxin heterogeneity. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1980
We have used flow dialysis to demonstrate binding of ATP and related compounds to diphtheria toxin. The results define a new site on the toxin molecule (the P site), which has distinctly different properties from the NAD+-binding site of the fragment A moiety.
Robert J. Collier, Stephen Lory
openaire   +3 more sources

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

open access: yesPediatric Discovery, EarlyView.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao   +6 more
wiley   +1 more source

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