Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]
Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Amessou, Mohamed +7 more
core +1 more source
New biosensors and transgenic mice for multiplex cGMP imaging
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters +6 more
wiley +1 more source
Diphtheria-like Diseases, Penyakit Zoonosis Sejenis Difteri yang Disebabkan oleh Corynebacterium Ulcerans yang Harus Diwaspadai [PDF]
Corynebacterium ulcerans merupakan bakteri penyebab zoonosis yang umumnya ditemukan pada binatang peliharaan atau ternak. Pada beberapa kasus dapat ditemukan pada manusia walaupun jarang dengan gejala yang ditimbulkan menunjukkan kemiripan dengan ...
P, R. H. (Rudi) +2 more
core
Diphtheria toxin-binding glycoproteins on hamster cells: candidates for diphtheria toxin receptors [PDF]
Diphtheria toxin-binding glycoproteins of high molecular weight (greater than 100,000) were identified on the surface of lymph node and thymus cells from hamsters, a diphtheria toxin-sensitive species. These diphtheria toxin-binding glycoproteins also interacted with CRM197 protein, which possesses toxin-blocking activity, but not with diphtheria ...
R L, Proia, L, Eidels, D A, Hart
openaire +2 more sources
Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino +10 more
wiley +1 more source
Sequence Analysis of Toxin Gene–Bearing Corynebacterium diphtheriae Strains, Australia
By conducting a molecular characterization of Corynebacterium diphtheriae strains in Australia, we identified novel sequences, nonfunctional toxin genes, and 5 recent cases of toxigenic cutaneous diphtheria.
Christine J. Doyle +5 more
doaj +1 more source
Special Libraries, February 1940 [PDF]
Volume 31, Issue 2https://scholarworks.sjsu.edu/sla_sl_1940/1001/thumbnail ...
Special Libraries Association
core +5 more sources
The Action of Diphtheria Toxin on Mice [PDF]
1. For the particular toxin tested, the intravenous m.l.d. for mice was 60 times and the intramuscular m.l.d. for mice 100 times, the guinea-pig sub cutaneous m.l.d.2. Antitoxin has the same neutralising power for toxin in mice as in guinea-pigs.
A T, Glenny, K, Allen
openaire +2 more sources
Mapping the murine TMJ glenoid fossa over development, homeostasis and in response to disease
The fibrocartilage of the murine glenoid fossa and condyle of the temporomandibular joint are shown to form at distinct times with distinct molecular identities. Changes in the condyle during disease lead to remodelling of the fossa to maintain joint alignment.
Ticha Tuwatnawanit +4 more
wiley +1 more source
A method for the screening of tetanus and diphtheria antibodies in serum using anatoxin (inactivated toxin) instead of toxin was developed as an alternative to the in vivo toxin neutralization assay based on the toxin-binding inhibition test (TOBI test).
M.H. Sonobe +8 more
doaj

