Results 71 to 80 of about 89,499 (267)
Diphtheria Antitoxin Levels in the Netherlands: a Population-Based Study
Emerging Infectious Diseases, 1999 In a population-based study in the Netherlands, diphtheria antitoxin antibodies were measured with a toxin-binding inhibition assay in 9,134 sera from the general population and religious communities refusing vaccination.
Hester E. de Melker +3 more
doaj +1 more source
Robust Humoral and Cellular Immune Responses to Pertussis in Adults After a First Acellular Booster Vaccination [PDF]
, 2018 IntroductionTo reduce the pertussis disease burden, nowadays several countries recommend acellular pertussis (aP) booster vaccinations for adults.
Anne-Marie Buisman +10 more
core +3 more sources
Journal of Sleep Research, EarlyView.ABSTRACT Narcolepsy type 1 is a chronic sleep disorder of putative autoimmune aetiology, primarily caused by the loss of orexin‐producing neurons in the hypothalamus. An additional 88% reduction in corticotropin‐releasing hormone‐immunoreactive neurons of the paraventricular nucleus has been recently observed in post‐mortem brains of individuals with ...
J. Zhou +7 more
wiley +1 more source
Postresuscitative Myocardial Impact of Anatoxin Preimmunization
Общая реаниматология, 2007 Objective: to study the impact of preimmunization with tetanus, diphtheria, and staphylococcal anatoxins on postresuscitative myocardial pathology.Materials and methods.
D. A. Yenikeyev +4 more
doaj +1 more source
Genomic analyses reveal two distinct lineages of Corynebacterium ulcerans strains [PDF]
, 2018 Corynebacterium ulcerans is an important zoonotic pathogen which is causing diphtheria-like disease in humans, globally. In this study, the genomes of three recently isolated C.
Burkovski, Andreas +8 more
core +1 more source
Observations on the Structure of Diphtheria Toxin
Journal of Biological Chemistry, 1971 Diphtheria toxin is synthesized as a single polypeptide chain with a molecular weight of about 62,000. After being secreted it may be partially digested by proteolytic enzymes released from the bacterial cells into the culture medium and purified preparations of toxin usually contain some of the proteolytic breakdown products.
D M, Gill, L L, Dinius
openaire +2 more sources
The role of immune responses and microbiota in adipose tissue homeostasis
The Journal of Physiology, EarlyView.Abstract figure legend Gut microbiota regulate white and brown adipose tissue homeostasis via modulation of gut hormone secretion, activation of pathogen‐associated pattern receptors and production of bioactive molecules and metabolites such as short‐chain fatty acids, endocannabinoids, amino acid derivates and bile acids, all of which affect ...
Shahar Azar, Barbara Rehermann
wiley +1 more source
Path Similarity Analysis: a Method for Quantifying Macromolecular Pathways
, 2015 Diverse classes of proteins function through large-scale conformational changes; sophisticated enhanced sampling methods have been proposed to generate these macromolecular transition paths. As such paths are curves in a high-dimensional space, they have
Beckstein, Oliver +3 more
core +3 more sources
Replacement, Reduction and Refinement of Animal Testing in the Quality Control of Human Vaccines [PDF]
, 2015 Vaccines are recognised as a highly cost effective tool for preventing infectious diseases. They are derived from biological sources and due to the complexity of composition and heterogeneity of products, vaccine lots undergo legally required quality ...
HALDER MARIA ELISABETH
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil +11 more
wiley +1 more source