Results 71 to 80 of about 358,147 (271)
Kidney International, 2013 Biomedical research often requires primary cultures of specific cell types, which are challenging to obtain at high purity in a reproducible fashion. Here we engineered the murine Rosa26 locus by introducing the diphtheria toxin receptor flanked by loxP ...
Jiankan Guo +6 more
semanticscholar +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
PROTEOMICS, EarlyView.ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
Postresuscitative Myocardial Impact of Anatoxin Preimmunization
Общая реаниматология, 2007 Objective: to study the impact of preimmunization with tetanus, diphtheria, and staphylococcal anatoxins on postresuscitative myocardial pathology.Materials and methods.
D. A. Yenikeyev +4 more
doaj +1 more source
Brazilian Journal of Medical and Biological Research, 2007 A method for the screening of tetanus and diphtheria antibodies in serum using anatoxin (inactivated toxin) instead of toxin was developed as an alternative to the in vivo toxin neutralization assay based on the toxin-binding inhibition test (TOBI test).
M.H. Sonobe +8 more
doaj
Diphtheria toxin has the properties of a lectin. [PDF]
Proceedings of the National Academy of Sciences, 1978 The inhibition of protein synthesis in Chinese hamster V79 cells by diphtheria toxin is antagonized by the lectins concanavalin A, succinylated concanavalin A, and wheat germ agglutinin but not by Proteus vulgaris phytohemagglutinin or abrus agglutinin. The effects of concanavalin A and wheat germ agglutinin are reversed by methyl alpha-mannoside and N-
Draper, Rockford K. +2 more
openaire +5 more sources
New biosensors and transgenic mice for multiplex cGMP imaging
British Journal of Pharmacology, EarlyView.Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters +6 more
wiley +1 more source
Cancer Science, EarlyView.Anti‐HPV vaccine activists claimed that aluminum (Al) adjuvants in HPV vaccines could cause immune abnormalities, leading to neurological diseases. We evaluated the cytokine and histology profiles following administrations of HPV vaccines and other viral vaccines containing adjuvants.
Reona Shiro +9 more
wiley +1 more source
Nature CommunicationsCorynebacterium ulcerans is an emerging zoonotic pathogen which causes diphtheria-like infections. Although C. ulcerans is found in multiple domestic and wild animal species, most human cases are linked with pets.
Chiara Crestani +7 more
doaj +1 more source
Functional verification of the diphtheria toxin A gene in a recombinant system
Journal of Animal Science and Biotechnology, 2012 Diphtheria toxin A (DTA), a segment of the diphtheria toxin (tox), inhibits protein synthesis in cells. When released from a cell, DTA is nontoxic and cannot enter other cells independently without the help of diphtheria toxin B.
Zhang Jingfeng +6 more
doaj +1 more source
Precursor in cotranslational secretion of diphtheria toxin [PDF]
Journal of Bacteriology, 1980 By extracellular labeling of peptides of intact Corynebacterium diphtheriae, followed by fractionation of the cells and chain completion by isolated polysomes, it is shown that diphtheria toxin is formed and secreted cotranslationally by membrane-bound polysomes; free polysomes from none.
W. P. Smith +3 more
openaire +3 more sources