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Syntheses of methotrexate-hybrid compounds for target profiling of small molecules with MASPIT [PDF]
De Clercq, Dries +4 more
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Natural 1,3‐Dipolar Cycloadditions
Angewandte Chemie International Edition, 2015[3+2] in the wild: Biomimetic natural product syntheses and theoretical considerations have indicated that 1,3-dipolar cycloadditions take place in nature. Now, the structure, biosynthesis, and function of a heavily modified prenylated flavin cofactor have been elucidated.
Martin, Baunach, Christian, Hertweck
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Extended dipolar cycloadditions
Journal of the Chemical Society, Perkin Transactions 1, 1975Whilst the simple azomethine imine (5) undergoes the expected 1,3-dipolar cycloaddition to acetylenic esters, the extended azomethine imines (1) undergo 1,5-rather than 1,3-dipolar cycloaddition to give benzo[c][1,2,5]-triazepino[1,2-a]cinnolines (2), possibly by a stepwise mechanism 2-Alkyl-2λ5σ3-naphtho[1,8-de]triazines (12) and 2λ4σ2-naphtho[1,8-cd ...
Stephanie F. Gait +4 more
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Journal of the Chemical Society, Chemical Communications, 1972
2-Methylnaphtho[1,8-de]triazine undergoes 1,11-dipolar (12π+ 2π) cycloaddition to acetylenic esters to give 2-methylacenaphtho[5,6-de]triazines, after spontaneous dehydrogenation.
C. W. Rees +2 more
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2-Methylnaphtho[1,8-de]triazine undergoes 1,11-dipolar (12π+ 2π) cycloaddition to acetylenic esters to give 2-methylacenaphtho[5,6-de]triazines, after spontaneous dehydrogenation.
C. W. Rees +2 more
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Asymmetric 1,3-dipolar cycloadditions
Tetrahedron, 2007AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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1994
Von Huisgen 1,2) wurde 1963 die 1,3-dipolare Cycloaddition 3–5) als Reaktionsprinzip zum Aufbau von Heterocyclen systematisiert. Man versteht darunter die Addition eines 1,3-Dipols 1, der aus den verschiedenen Kombinationen von Kohlenstoff-, Stickstoff- und Sauerstoffatomen bestehen kann und vier nicht dienische π-Elektronen umfast, an eine ...
Thomas Laue, Andreas Plagens
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Von Huisgen 1,2) wurde 1963 die 1,3-dipolare Cycloaddition 3–5) als Reaktionsprinzip zum Aufbau von Heterocyclen systematisiert. Man versteht darunter die Addition eines 1,3-Dipols 1, der aus den verschiedenen Kombinationen von Kohlenstoff-, Stickstoff- und Sauerstoffatomen bestehen kann und vier nicht dienische π-Elektronen umfast, an eine ...
Thomas Laue, Andreas Plagens
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1,3-Dipolar Cycloadditions in Aqueous Media
HETEROCYCLES, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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Boryl Azides in 1,3-Dipolar Cycloadditions
The Journal of Organic Chemistry, 2014The 1,3-dipolar cycloaddition reaction of boron azides with alkynes has been investigated experimentally and computationally. At room temperature pinBN3 (pin = pinacolato) reacts with the strained triple bond of cyclooctyne with formation of an oligomeric boryl triazole.
Matthias, Müller +2 more
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Rhodium-Mediated Dipolar Cycloaddition of Diazoquinolinediones
The Journal of Organic Chemistry, 1999As an entry to furoquinoline structures of natural origin, the rhodium-mediated dipolar cycloaddition of diazoquinolinediones with alkenes and alkynes has been examined. Because of the unsymmetrical nature of the diazo compounds, both linear and angular furoquinoline products are possible.
Michael C., Pirrung, Florian, Blume
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