Results 41 to 50 of about 99,145 (214)

Domino Multicomponent Approach for the Synthesis of Functionalized Spiro-Indeno[1,2-b]quinoxaline Heterocyclic Hybrids and Their Antimicrobial Activity, Synergistic Effect and Molecular Docking Simulation

open access: yesMolecules, 2019
An expedient synthesis of hitherto unexplored novel hybrid heterocycles comprising dispiropyrrolidine, N-styrylpiperidone and indeno[1,2-b]quinoxaline units has been developed via domino multicomponent 1,3-dipolar cycloaddition strategy employing a new ...
Abdulrahman I. Almansour   +8 more
doaj   +1 more source

Photocatalysis‐Triggered Click Reactions and Applications

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Photoclick chemistry offers broad applications ranging from materials science to bioconjugation, with precise spatiotemporal control over click reactions. Initially limited to UV activation, recent advances have extended photoclick processes to the visible and NIR regions thanks to the photocatalysis.
Margaux Walter   +2 more
wiley   +1 more source

Bromonitroalkanes in Organic Synthesis

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
α,α‐Bromonitroalkanes (BNAs) exhibit chameleon‐like reactivity, serving as carbene, radical, carbanion, and carbocation synthons. This mini‐review summarizes the different reaction modes and highlights recent developments in thermal and photochemical processes. α,α‐Bromonitroalkanes (BNAs) exhibit chameleon‐like reactivity, serving as carbene, radical,
Magdalena Koch, Oliver Reiser
wiley   +1 more source

One Step Regioselective Synthesis of 5-Aminoisoxazoles from Nitrile Oxides and α-Cyanoenamines

open access: yesMolecules, 2004
The 1,3-dipolar cycloaddition of nitrile oxides to 1-cyanoenamines gives 5-aminoisoxazoles regioselectively. Moderate to good yields could be obtained depending on the method used to generate the nitrile oxides. The intermediate isoxazolines could not be
Aïcha Derdour   +2 more
doaj   +1 more source

dipolar cycloaddition

open access: yes, 2008
Citation: 'dipolar cycloaddition' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.D01754 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Nano‐Optical Biomolecular Interaction Sensing Within Complex Media via Peptide Hybrid Ligand Conjugation

open access: yesSmall, EarlyView.
We have designed a new type of nanoparticle‐based optical biosensor whose surface has been engineered with peptide‐polymer hybrids so that sensing of small protein‐protein interactions can be performed in simple buffers and complex biological liquids including animal and human serum. Measurements can be performed simply by mixing nanosensors with media
Gurunath Apte   +10 more
wiley   +1 more source

Farnesyltransferase Enables Modular Assembly of Dual‐Functional Nanobody Conjugates for in Vivo Imaging of Inflammation

open access: yesAngewandte Chemie, Volume 138, Issue 42, 12 October 2026.
A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy   +7 more
wiley   +2 more sources

1,3-Dipolar cycloadditions of azomethine imines

open access: yesOrganic & Biomolecular Chemistry, 2015
Azomethine imines react with alkenes and alkynes to give pyrazolines, pyrazolidines, pyrazolopyridines, indazoloisoquinolines, pyrazolo[1,5- a ]isoquinolines and pyrazolopyrazolones through regio-, stereo- and enantioselective 1,3-dipolar cycloadditions.
Carmen, Nájera   +2 more
openaire   +3 more sources

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

open access: yesThe Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra   +2 more
wiley   +1 more source

Silicon-Tethered 1,3-Dipolar Cycloaddition of 4-Hydroxy-2-isoxazoline 2-Oxides

open access: yes, 1996
Silicon-tethered 1,3-dipolar cycloaddition of 4-hydroxy-2-isoxazoline 2 ...
Landuzzi, Andrea   +7 more
core   +1 more source

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