Results 51 to 60 of about 5,680 (182)
PharmaceuticalsBackground: This research centers on the development and spectroscopic characterization of new quinazolin-4(3H)-one-isoxazole derivatives (5a–e). The aim was to investigate the regioselectivity of the 1,3-dipolar cycloaddition involving arylnitriloxides ...
Yassine Rhazi +13 more
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5-Benzoyl-N,4-diphenyl-4,5-dihydro-1H-pyrazole-3-carboxamide
Acta Crystallographica Section E, 2009 The title compound, C23H19N3O2, was synthesized by the 1,3-dipolar cycloaddition reaction of N-phenyl-α-diazoacetamide and chalcone. In the molecule, the pyrazoline ring assumes an envelope conformation.
Long He
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The Chemical Record, EarlyView.This publication describes how R. B. Woodward and Roald Hoffmann crafted their masterpiece publications. Illustrations include Woodward's first draft of the famous “Violations There are none. Nor can violations be expected of so fundamental a principle of maximum bonding.” Original but discarded text shows the stepwise paths toward the W‐H masterpieces.
Jeffrey I. Seeman
wiley +1 more source
An overview of the cycloaddition chemistry of fulvenes and emerging applications
Beilstein Journal of Organic Chemistry, 2019 The unusual electronic properties and unique reactivity of fulvenes have interested researchers for over a century. The propensity to form dipolar structures at relatively low temperatures and to participate as various components in cycloaddition ...
Ellen Swan +2 more
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Ultrasound-promoted synthesis of novel fused heterocycles by criss-cross cycloaddition
Journal of Saudi Chemical Society, 2016 This work reports a novel and highly efficient methodology for the synthesis of perhydrotriazolotriazoledithions from two successive 1,3-dipolar cycloaddition under ultrasound irradiation.
Javad Safari +2 more
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Late‐Stage Functionalization of Peptides on the Solid Phase
Angewandte Chemie International Edition, Volume 65, Issue 31, 27 July 2026.Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source
1,3-Dipolar Cycloadditions of N-Benzyl Furfuryl Nitrones with Electron-rich Alkenes
Molecules, 2000 The 1,3-dipolar cycloaddition reaction of N-benzyl-C-(2-furyl)nitrones with electron-rich alkenes gives preferentially trans-substituted 3,5-disubstituted isoxazolidines (endo approach).
Tomas Tejero +3 more
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Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview
Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati +4 more
wiley +1 more source
Natural Product Communications, 2018 An one-step and efficient access to the new dammarane A-quinolones by ozonolysis of 2,3-indolodipterocarpol at 0°C through the 1,3-dipolar cycloaddition of ozone to the C2-C3 double bond of the triterpenoid core is reported.
Irina E. Smirnova +3 more
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One-pot Microwave-Assisted Synthesis of 1H-Phenanthro[9,10- d][1,2,3]triazole
Molbank, 2008 In this study, a fast and good yield one-pot microwave-assisted synthesis (45 seconds) of 1H-phenanthro[9,10-d][1,2,3]triazole by a 1,3-dipolar cycloaddition reaction of sodium azide and 9-bromophenanthrene in the presence of potassium tert-butoxide in ...
Mehrak Faraji, Avat Arman Taherpour
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