Effects of dipyrone on the digestive tract [PDF]
Brazilian Journal of Medical and Biological Research, 2019 Dipyrone (metamizole), acting through its main metabolites 4-methyl-amino-antipyrine and 4-amino-antipyrine, has established analgesic, antipyretic, and spasmolytic pharmacological effects, which are mediated by poorly known mechanisms.
E.F. Collares, L.E.A. Troncon
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Antipyretic effect of oral dipyrone (Metamizole) compared to oral ibuprofen in febrile children: a systematic review and meta-analysis [PDF]
BMC PediatricsBackground Dipyrone (Metamizole) is a potent pain reliever and fever reducer with muscle relaxant properties, most commonly used as an analgesic and antipyretic agent.
Maged Alnajar +5 more
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Brazilian Journal of Otorhinolaryngology, 2021 Introduction: Tonsillectomy is the 2nd most common outpatient surgery performed on children in the United States of America. Its main complication is pain, which varies in intensity from moderate to severe.
Maira Isis S. Stangler +3 more
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Neutropenia, agranulocytosis and dipyrone [PDF]
São Paulo Medical Journal, 2005 CONTEXT: Neutropenia and agranulocytosis may be defined as granulocyte counts of less than 1,500/mm³ and 500/mm³, respectively. Agranulocytosis is a rare and serious disease often caused by drugs. Its mortality rate is around 10%.
Nelson Hamerschlak +1 more
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Cross-Reactivity: a Case of Paracetamol-Induced Generalized Bullous Fixed Drug Eruption Followed by Dipyrone-Induced Fixed Drug Eruption [PDF]
Clinical, Cosmetic and Investigational DermatologyYuanyuan Wang,1,* Huan Xue,2,* Hejun Dai,1 Lianjuan Yang1 1Department of Medical Mycology, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China; 2Department
Wang Y, Xue H, Dai H, Yang L
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“Eco-friendly HPLC method for analysis of dipyrone and hyoscine in different matrices with biomonitoring” [PDF]
Scientific ReportsA selective, precise, and accurate reversed HPLC method has been developed and validated for simultaneous separation and determination of two veterinary drugs, dipyrone and hyoscine, in their combined dosage form in the presence of their official ...
Reem A. El kalla +4 more
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The antipyretic effectiveness of dipyrone in the intensive care unit: A retrospective cohort study.
PLoS ONE, 2022 IntroductionDipyrone (metamizol) is regularly used in critical care for pain and fever treatment, especially in Germany and Spain. However, indication for antipyretic therapy in critically ill patients is currently unclear and data for both the risk and ...
Hans-Jörg Gillmann +3 more
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Pharmacokinetic Profile of Two Active Dipyrone Metabolites, 4-Methylaminoantipyrine (MAA) and 4-Aminoantipyrine (AA), Following Intravenous Administration in Dogs: A Preliminary Study. [PDF]
Animals (Basel)Mouta AN +7 more
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Electrochemical Determination of Dipyrone Using a Cold-Plasma-Treated Graphite Sheet Electrode. [PDF]
ACS OmegaPereira JFS +7 more
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Effects of intratesticular injection of zinc-based solution in rats in combination with anti-inflammatory and analgesic drugs during chemical sterilization [PDF]
Veterinary World, 2018 Aim: Chemical sterilization is a non-surgical method of contraception based on compounds injected into the testis to induce infertility. However, these injections can cause discomfort and pain able to impair the recovery of animals after this treatment ...
Simone Regina Barros de Macedo +7 more
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