Lack of influence of the COX inhibitors metamizol and diclofenac on platelet GPIIb/IIIa and P-selectin expression [PDF]
Background The effect of non-steroidal anti-inflammatory drugs (NSAIDs) for reduced platelet aggregation and thromboxane A2 synthesis has been well documented. However, the influence on platelet function is not fully explained.
Dirk Scheinichen +34 more
core +1 more source
Do endogenous opioids and nitric oxide participate in the anticonvulsant action of dipyrone?
It was previously reported that systemic administration of dipyrone inhibited the tonic component of generalized tonic-clonic seizures in both the electroshock and the audiogenic seizure models.
G.M.L. Reis +3 more
doaj +1 more source
Behaviour of emerging contaminants in sewage sludge after anaerobic digestion [PDF]
Nowadays, there is an increasing concern over the presence of contaminants in the aquatic environment, where they can be introduced from wastewater after their incomplete removal in the treatment plants.
Boix Sales, Clara +7 more
core +1 more source
EFFECT OF DIPYRONE ON THE RENAL CLEARANCE AND URINARY EXCRETION OF NORFLOXACIN IN SHEEP [PDF]
The effect of dipyrone on the renal clearance and urinary excretion of norfloxacin was investigated in eight healthy female sheep. In each animal, after a single intramuscular administration of norfloxacin, 5 mg/kg body weight, a wash out period of seven
I. Javed, M. Shahzad, T. Khaliq, F. H. Khan, F. Muhammad, B. Aslam and Z. Iqbal
doaj
Post-Discharge Opioid Prescribing After Elective Colorectal Resection: An International Survey. [PDF]
Excessive opioid prescribing after colorectal surgery can lead to adverse events and contribute to the opioid crisis. Understanding international prescribing patterns is essential for guiding practice and future research. The Analgesia After Colorectal Surgery (ACORE) survey aimed to characterize international opioid prescribing practices after ...
Olleik G +23 more
europepmc +2 more sources
Investigation of pharmaceutical metabolites in environmental waters by LC-MS/MS [PDF]
Pharmaceuticals, once ingested, are commonly metabolized in the body into more polar and soluble forms. These compounds might not be completely removed in the wastewater treatment plants and consequently being discharged into the aquatic ecosystem.
GRACIA LOR, EMMA +4 more
core +1 more source
Pethidine in Low Doses versus Dipyrone for Pain Relief in Labor: A Randomized Controlled Trial [PDF]
Objective To compare low doses of pethidine with dipyrone in labor analgesia. Methods In a randomized prospective study conducted by Universidade de Fortaleza, in the state of Ceará, Brazil, between May and December 2016, 200 full-term parturients ...
Rogevando Rodrigues Nunes +1 more
doaj +1 more source
Fast determination of 40 drugs in water using large volume direct injection liquid chromatography–tandem mass spectrometry [PDF]
This work describes a rapid analytical method based on direct sample injection of water samples for the simultaneous identification/quantification of 40 emerging compounds, including pharmaceuticals and drugs of abuse.
Aranda Mares, José Luis +6 more
core +1 more source
Analgesic Management of Pain in Elite Athletes: A Systematic Review [PDF]
Objective: To identify the prevalence, frequency of use, and effects of analgesic pain management strategies used in elite athletes. Design: Systematic literature review.
Danielson, Elizabeth C. +6 more
core +1 more source
CONTEXT AND OBJECTIVE: Dipyrone is a widely used over-the-counter antipyretic in Latin America, and elsewhere among Latin immigrants. Despite limited evidence, physicians often prescribe oral ibuprofen or intramuscular dipyrone as the most effective ...
Judith Prado +4 more
doaj +1 more source

