Hepatic Markers and Immunological Trajectories in a Cohort of Patients with HIV and Hepatitis C Virus Coinfection Treated with Direct-Acting Antivirals. [PDF]
Simoncini G +6 more
europepmc +1 more source
What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady +6 more
wiley +1 more source
Impact of hepatitis C virus genotype on the efficacy of the direct-acting antivirals in chronic kidney disease patients in West Bengal, India. [PDF]
Bakshi S +7 more
europepmc +1 more source
Hepatitis C virus care continuum: integrating point of care RNA assay and direct acting antivirals. [PDF]
Fatima R.
europepmc +1 more source
The Impact of Organic Anion-Transporting Polypeptide (OATP) Variants on the Side Effects of Direct-Acting Antivirals in Hepatitis C Patients. [PDF]
Altintas Z, Altintas E.
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The effect of cognitive emotion regulation on direct-acting antivirals adherence in patients with hepatitis C. [PDF]
Turcu-Stiolica A +7 more
europepmc +1 more source
Hepatocellular Carcinoma After HCV Eradication with Direct-Acting Antivirals: A Reappraisal Based on New Parameters to Assess the Persistence of Risk. [PDF]
Fassio E +5 more
europepmc +1 more source
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Antiviral resistance and direct-acting antiviral agents for HCV
Antiviral Therapy, 2012Direct-acting antiviral (DAA) agents specifically target viral proteins. Two DAAs have been already been approved for the treatment of HCV infection and many more are in development. DAA treatment of HCV infection, however, leads to the selection of viral variants (produced by the error-prone HCV polymerase) that are resistant to the DAA agent in use ...
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Direct-acting antiviral retreatment patterns for hepatitis C
Journal of Managed Care & Specialty Pharmacy, 2022BACKGROUND: Despite the strong efficacy of direct-acting antivirals (DAAs) against the hepatitis C virus, many patients require a second regimen of DAA treatment. However, limited research exists to characterize rates of retreatment across different DAA agents or potential factors that may increase retreatment risk.
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