Results 41 to 50 of about 489,553 (296)
Evolutionary Approaches to Study Cytochrome c Peroxidase
CHIMIA, 2001 Directed molecular evolution of enzymes and proteins has emerged as an extremely powerful method to create proteins with novel properties, both for practical applications as well as for mechanistic studies.
André Iffland +3 more
doaj +2 more sources
Recent progress in directed evolution of stereoselective monoamine oxidases
Bioresources and Bioprocessing, 2019 Monoamine oxidases (MAOs) use molecular dioxygen as oxidant to catalyze the oxidation of amines to imines. This type of enzyme can be employed for the synthesis of primary, secondary, and tertiary amines by an appropriate deracemization protocol ...
Jiaqi Duan +5 more
doaj +1 more source
Biomolecules, 2020 Two photoactivatable near infrared fluorescent proteins (NIR FPs) named “PAiRFP1” and “PAiRFP2” are formed by directed molecular evolution from Agp2, a bathy bacteriophytochrome of Agrobacterium tumefaciens C58.
Faez Iqbal Khan +4 more
doaj +1 more source
Structure-Guided Recombination Creates an Artificial Family of Cytochromes P450 [PDF]
, 2006 Creating artificial protein families affords new opportunities to explore the determinants of structure and biological function free from many of the constraints of natural selection.
Arnold, Frances H. +5 more
core +1 more source
Expanded molecular diversity generation during directed evolution by trinucleotide exchange (TriNEx) [PDF]
Nucleic Acids Research, 2008 Trinucleotide exchange (TriNEx) is a method for generating novel molecular diversity during directed evolution by random substitution of one contiguous trinucleotide sequence for another. Single trinucleotide sequences were deleted at random positions in a target gene using the engineered transposon MuDel that were subsequently replaced with a ...
Baldwin, Amy Joy +3 more
openaire +3 more sources
Molecular dynamic simulation on temperature evolution of SiC under directional microwave radiation
Journal of Physics: Condensed Matter, 2022 Abstract Silicon carbide (SiC) is widely used as the substrate for high power electronic devices as well as susceptors for microwave (MW) heating. The dynamics of microwave interaction with SiC is not fully understood, especially at the material boundaries.
Khan, TA +7 more
openaire +3 more sources
Information content of colored motifs in complex networks [PDF]
, 2011 We study complex networks in which the nodes of the network are tagged with different colors depending on the functionality of the nodes (colored graphs), using information theory applied to the distribution of motifs in such networks.
Arend Hintze +4 more
core +1 more source
, 2010 Using coarse-grained molecular-dynamics simulations, a generic styrene-(block)-butadiene-(block)-styrene (SBS) triblock copolymer under lamellar conformation is used in order to investigate the mutual entanglement evolution when a structure of ...
Léonforte, F.
core +1 more source
Selection of chromosomal DNA libraries using a multiplex CRISPR system. [PDF]
, 2014 The directed evolution of biomolecules to improve or change their activity is central to many engineering and synthetic biology efforts. However, selecting improved variants from gene libraries in living cells requires plasmid expression systems that ...
Arkin, Adam P +10 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij +11 more
wiley +1 more source