Results 51 to 60 of about 493,855 (292)
Microorganisms, 2020 To improve the thermostability of tryptophan synthase, the molecular modification of tryptophan synthase was carried out by rational molecular engineering.
Lisheng Xu +3 more
doaj +1 more source
Structure-Guided Directed Evolution of Highly Selective P450-Based Magnetic Resonance Imaging Sensors for Dopamine and Serotonin [PDF]
, 2012 New tools that allow dynamic visualization of molecular neural events are important for studying the basis of brain activity and disease. Sensors that permit ligand-sensitive magnetic resonance imaging (MRI) are useful reagents due to the noninvasive ...
Arnold, Frances H. +8 more
core +2 more sources
Molecular dynamic simulation on temperature evolution of SiC under directional microwave radiation
Journal of Physics: Condensed Matter, 2022 Abstract Silicon carbide (SiC) is widely used as the substrate for high power electronic devices as well as susceptors for microwave (MW) heating. The dynamics of microwave interaction with SiC is not fully understood, especially at the material boundaries.
Khan, TA +7 more
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Directed Flow in Microscopic Models in Relativistic A+A Collisions
Universe, 2019 Evolution of directed flow of charged particles produced in relativistic heavy-ion collisions at energies 4 ≤ s ≤ 19.6 GeV is considered within two microscopic transport models, ultra-relativistic quantum molecular dynamics (UrQMD) and ...
Larissa Bravina +4 more
doaj +1 more source
In Vivo Evolution of Butane Oxidation by Terminal Alkane Hydroxylases AlkB and CYP153A6 [PDF]
, 2009 Enzymes of the AlkB and CYP153 families catalyze the first step in the catabolism of medium-chain-length alkanes, selective oxidation of the alkane to the 1-alkanol, and enable their host organisms to utilize alkanes as carbon sources.
Arnold, Frances H. +3 more
core +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes
eLife, 2019 Genetic variation among orthologous proteins can cause cryptic phenotypic properties that only manifest in changing environments. Such variation may impact the evolvability of proteins, but the underlying molecular basis remains unclear.
Florian Baier +9 more
doaj +1 more source
Partitioning the fitness components of RNA populations evolving in vitro. [PDF]
PLoS ONE, 2013 All individuals in an evolving population compete for resources, and their performance is measured by a fitness metric. The performance of the individuals is relative to their abilities and to the biotic surroundings--the conditions under which they are ...
Carolina Díaz Arenas, Niles Lehman
doaj +1 more source
Surface-Directed Spinodal Decomposition: A Molecular Dynamics Study
, 2012 We use molecular dynamics (MD) simulations to study surface-directed spinodal decomposition (SDSD) in unstable binary ($AB$) fluid mixtures at wetting surfaces.
Das, Subir K. +2 more
core +1 more source