Results 11 to 20 of about 87,813 (301)

Effect of Trehalose and Lactose Treatments on the Freeze-Drying Resistance of Lactic Acid Bacteria in High-Density Culture

open access: yesMicroorganisms, 2022
Freeze-drying is a commonly used method in commercial preparations of lactic acid bacteria. However, some bacteria are killed during the freeze-drying process. To overcome this, trehalose and lactose are often used as protective agents.
Shumao Cui   +7 more
doaj   +1 more source

Conformational Consequences for Compatible Osmolytes on Thermal Denaturation

open access: yesLife, 2021
Compatible osmolytes are a broad class of small organic molecules employed by living systems to combat environmental stress by enhancing the native protein structure. The molecular features that make for a superior biopreservation remain elusive. Through
Nimesh Shukla   +3 more
doaj   +1 more source

Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides [PDF]

open access: yes, 2020
Despite evident regulatory roles of heparan sulfate (HS) saccharides in numerous biological processes, definitive information on the bioactive sequences of these polymers is lacking, with only a handful of natural structures sequenced to date.
Grabarics, Márkó   +9 more
core   +1 more source

A Validated HPLC-RID Method for Quantification and Optimization of Total Sugars: Fructose, Glucose, Sucrose, and Lactose in Eggless Mayonnaise

open access: yesSeparations, 2023
Mayonnaise is an oil-in-water emulsion containing 70–80% finely dispersed droplets of oil in a continuous phase of water. Since mayonnaise has a sour and acidic taste, its sugar profile is barely noticed and thus often disregarded.
Mrityunjay Tiwari   +4 more
doaj   +1 more source

Bioconjugation of Carbohydrates to Gelatin Sponges Promoting 3D Cell Cultures

open access: yesBiomimetics, 2023
Gelatin sponges are widely employed as hemostatic agents, and are gaining increasing interest as 3D scaffolds for tissue engineering. To broaden their possible application in the field of tissue engineering, a straightforward synthetic protocol able to ...
Antonietta Pepe   +5 more
doaj   +1 more source

Crystal packing in three related disaccharides: precursors to heparan sulfate oligosaccharides

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
The three title compounds form part of a set of important precursor dissacharides which lead to novel therapeutics, in particular for Alzheimer's disease.
Graeme J. Gainsford   +3 more
doaj   +1 more source

Prophylaxis of Intranasally Induced Pollen Allergy in a BALB/C Mouse Model Using a Potential Prebiotic β-1, 4 Mannobiose

open access: yesAllergology International, 2013
Background: Dietary supplementation with unique prebiotic nondigestible carbohydrates has been shown to suppress allergy. In the present study, the prophylactic efficacy of a disaccharide p-1, 4 mannobiose (MNB) in a BALB/C mouse model of intranasally ...
Chengbo Yang   +5 more
doaj   +1 more source

Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains from Swim Bladder: Isolation, Structural Analysis, and Anticoagulant Activity

open access: yesMarine Drugs, 2023
Glycosaminoglycans (GAGs) with unique structures from marine animals show intriguing pharmacological activities and negligible biological risks, providing more options for us to explore safer agents.
Yue Yao   +7 more
doaj   +1 more source

New Benzoxazine Secondary Metabolites from an Arctic Actinomycete

open access: yesMarine Drugs, 2014
Two new secondary metabolites, arcticoside (1) and C-1027 chromophore-V (2), were isolated along with C-1027 chromophore-III and fijiolides A and B (3–5) from a culture of an Arctic marine actinomycete Streptomyces strain.
Kyuho Moon   +9 more
doaj   +1 more source

Disaccharide-tag for highly sensitive identification of O-GlcNAc-modified proteins in mammalian cells.

open access: yesPLoS ONE, 2022
O-GlcNAcylation is the only sugar modification for proteins present in the cytoplasm and nucleus and is thought to be involved in the regulation of protein function and localization.
Hirohito Abo   +6 more
doaj   +2 more sources

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