Results 141 to 150 of about 26,182 (278)

Age‐Associated Decline in Autophagy Pathways in the Retinal Pigment Epithelium and Protective Effects of Topical Trehalose in Light‐Induced Outer Retinal Degeneration in Mice

open access: yesAging Cell, EarlyView.
Transcriptomic analyses reveal an age‐related decline in autophagy pathways in RPE/choroid. These pathways remain unchanged in early AMD but become bidirectionally dysregulated in later stages, along with increased RPE loss. Pre‐treatment with trehalose eyedrops enhances RPE autophagy flux and prevents light‐induced outer retinal degeneration in mice ...
Katherine Cox   +13 more
wiley   +1 more source

Multi-omic analysis of meningeal cerebral amyloid angiopathy reveals enrichment of unsubstituted glucosamine and extracellular proteins. [PDF]

open access: yesJ Neuropathol Exp Neurol
Mayfield JE   +15 more
europepmc   +1 more source

The molecular basis of lactase persistence: Linking genetics and epigenetics

open access: yesAnnals of Human Genetics, EarlyView.
Abstract Lactase persistence (LP) — the genetic trait that determines the continued expression of the enzyme lactase into adulthood — has undergone recent, rapid positive selection since the advent of animal domestication and dairying in some human populations.
Céleste E. Cohen   +2 more
wiley   +1 more source

Synthesis of 3,4-disaccharides from pyranosides and furanosides monomers, a novel class of potential bioactive disaccharides

open access: yesARKIVOC, 2007
Muhammad Abbas   +2 more
doaj   +1 more source

Can the choice of artificial tears harm patients? A narrative review with an overview of the Nordic market

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To provide an overview of artificial tears marketed in the following Nordic countries: Denmark, Finland, Norway, Iceland and Sweden. Furthermore, this review aimed to highlight the different preservatives and other constituents found in artificial tears in the Nordic market, focussing on adverse effects.
K. N. Mikha   +9 more
wiley   +1 more source

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