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Pathogenesis of Intervertebral Disc Degeneration

2013
It is estimated that as much as 84 % of the population will suffer from low back pain (LBP) at some point in their lifetime (Walker 2000), with around 10 % of sufferers being chronically disabled. As such LBP is one of the most prevalent musculoskeletal conditions affecting Western society (Stewart et al.
Hoyland, JA   +2 more
openaire   +2 more sources

Genotoxic parameters of human degenerated intervertebral discs are linked to the pathogenesis of disc degeneration

Journal of Neurosurgical Sciences
Degenerative disc disease (DDD) is a prevalent disorder that brings great incapacity and morbidity to the world's population. Its pathophysiology is not fully understood. DNA damage can influence this process, but so far, there have been few studies to evaluate this topic and its true importance in DDD, as well as whether there is a relation between ...
Charles A, Carazzo   +5 more
openaire   +2 more sources

Myxomatous degeneration of the lumbar intervertebral disc

Neurosurgery, 1985
Abstract Sixteen patients were operated on for lumbar pain and pain radiating into the sciatic nerve distribution. In all 16, when the anulus fibrosus was incised, soft, gray disc material extruded under pressure like toothpaste being squeezed from a tube.
openaire   +2 more sources

Nanobacteria and intervertebral disc degeneration

Medical Hypotheses, 2005
Hossein, Eskandary   +2 more
openaire   +2 more sources

The molecular basis of intervertebral disc degeneration

Spine Journal, 2013
Chadi Tannoury, Christopher Kepler
exaly  

The cell biology of intervertebral disc aging and degeneration

Ageing Research Reviews, 2007
Chang-Qing Zhao
exaly  

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