Results 71 to 80 of about 118,573 (345)

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Pathologic Features of the Intervertebral Disc in Young Nova Scotia Duck Tolling Retrievers Confirms Chondrodystrophy Degenerative Phenotype Associated With Genotype. [PDF]

open access: yes, 2019
Chondrodystrophy results in predictable and progressive biochemical and structural changes to the intervertebral disc, resulting in early onset degeneration and dystrophic mineralization of the disc.
Bannasch, Danika   +5 more
core  

Open Gromov-Witten invariants, mirror maps, and Seidel representations for toric manifolds [PDF]

open access: yes, 2016
Let $X$ be a compact toric K\"ahler manifold with $-K_X$ nef. Let $L\subset X$ be a regular fiber of the moment map of the Hamiltonian torus action on $X$.
Chan, Kwokwai   +3 more
core   +1 more source

Von Economo Neuron Loss in Frontotemporal Dementia: A Meta‐Analysis of Neuropathological Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Von Economo neurons (VENs) have been reported to be vulnerable to neurodegeneration in frontotemporal dementia (FTD), particularly the behavioral variant (bvFTD), but these findings have not been systematically assessed across independent brain banks.
Daniel Talmasov   +2 more
wiley   +1 more source

Imaging observation of intervertebral disc degeneration in patients with old thoracolumbar fracture-related kyphotic deformity

open access: yesScientific Reports
Old thoracolumbar fracture with kyphosis (OTLFK) often results in low back pain, with intervertebral disc degeneration being a significant contributor.
Xi-long Cui   +9 more
doaj   +1 more source

Lumbar Degenerative Disc Disease: Current and Future Concepts of Diagnosis and Management

open access: yesAdvances in Orthopedics, 2012
Low back pain as a result of degenerative disc disease imparts a large socioeconomic impact on the health care system. Traditional concepts for treatment of lumbar disc degeneration have aimed at symptomatic relief by limiting motion in the lumbar spine,
Fadi Taher   +6 more
doaj   +1 more source

Expression and Localization of aquaporin‐1 in Temporomandibular Joint Disc with Internal Derangement [PDF]

open access: yes, 2012
Background: Internal derangement is the most frequent arthropathy affecting the temporomandibular joint, where its commonest form is anterior disc displacement with or without reduction.
Almeida, Luis Eduardo   +7 more
core   +2 more sources

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

The preoperative predictors for subsequent degeneration in L5-S1 disc after long fusion arthrodesis terminating at L5 in patients with adult scoliosis: focus on spinopelvic parameters

open access: yesJournal of Orthopaedic Surgery and Research, 2018
Background The subsequent L5-S1 disc degeneration associated with long fusion arthrodesis terminating at L5 in patients with adult scoliosis has been a common concern.
Changzhi Yan   +4 more
doaj   +1 more source

Degeneration of the intervertebral disc with new approaches for treating low back pain. [PDF]

open access: yes, 2015
This review paper discusses the process of disc degeneration and the current understanding of cellular degradation in patients who present with low back pain.
Binch, AL   +3 more
core  

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