Results 141 to 150 of about 192,797 (169)

Modeling Heart Diseases on a Chip: Advantages and Future Opportunities

Circulation Research, 2023
Heart disease is a significant burden on global health care systems and is a leading cause of death each year. To improve our understanding of heart disease, high quality disease models are needed. These will facilitate the discovery and development of new treatments for heart disease.
Omar Mourad, Ryan Yee, Mengyuan Li, Sara S. Nunes   +3 more
openaire   +2 more sources

Degenerative disease‐on‐a‐chip: Developing microfluidic models for rapid availability of newer therapies

Biotechnology Journal, 2021
AbstractBackgroundUnderstanding the pathophysiology of degenerative diseases pertaining to nervous system, ocular region, bone/cartilage, and muscle are still being comprehended, thus delaying the availability of targeted therapies.Purpose and ScopeNewer micro‐physiological systems (organ‐on‐chip technology) involves development of more sophisticated ...
Devashree Jahagirdar, Prachi Bangde, Ratnesh Jain, Prajakta Dandekar   +3 more
openaire   +2 more sources

Shear and endothelial induced late-stage calcific aortic valve disease-on-a-chip develops calcium phosphate mineralizations

Lab on a Chip, 2022
We fabricated PDMS microfluidics with an internal collagen hydrogel to develop a bench-top model of calcific aortic valve disease.
Melissa Mendoza, Mei-Hsiu Chen, Peter Huang, Gretchen J. Mahler   +3 more
openaire   +2 more sources

Organ-, body- and disease-on-a-chip systems

Lab on a Chip, 2017
Thought leader Michael Shuler introduces the Lab on a Chip organ, body and disease on a chip thematic collection.
openaire   +2 more sources

Advances in organ-, body-, and disease-on-a-chip systems

Lab on a Chip, 2019
Thought leader Michael Shuler provides an update on the Lab on a Chip organ-, body- and disease- on-a-chip thematic collection.
openaire   +2 more sources

Abstract Mo089: Fontan-Associated Liver Disease On A Chip

Circulation Research
Introduction: The Fontan procedure is performed in children with single ventricle physiology, and has led to excellent short-term palliation and survival rates but at the cost of long-term complications. Fontan-associated liver disease (FALD) results from hemodynamic changes following the Fontan procedure, leading to ...
Sarah Rezapourdamanab, Yamini Singh, Sophia Norton, Boeun Hwang, Linqi Jin, Mehdi Salar Amoli, Shweta Karnik, Reza Avazmohammadi, Sunder Neelakantan, Lakshmi Dasi, Rene Romero, Holly Bauser Heaton, Vahid Serpooshan   +12 more
openaire   +1 more source

Mo1789 GUT MICROBIOTA DIRECTLY CONTROLS EPITHELIAL OXIDATIVE STRESS AND INFLAMMATORY RESPONSES IN A PATIENT-SPECIFIC CROHN'S DISEASE-ON-A-CHIP

Gastroenterology, 2023
Nam Than, Woojung Shin, Dennis Wylie, Yoko M. Ambrosini, Soyoun Min, Yong Cheol Shin, Hong Koh, Linda A. Feagins, Hyun Jung Kim   +8 more
openaire   +1 more source

Faculty Opinions recommendation of A Real-Time Sensing System for Monitoring Neural Network Degeneration in an Alzheimer's Disease-on-a-Chip Model.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2022
Robert Petersen, Bhairavi Srinageshwar
openaire   +1 more source

Clamping strategies for organ-on-a-chip devices

Nature Reviews Materials, 2023
Lorenzo Moroni, Stefan Giselbrecht
exaly  

Adoption of organ-on-chip platforms by the pharmaceutical industry

Nature Reviews Drug Discovery, 2021
Paul Vulto
exaly