Results 31 to 40 of about 92,114,249 (286)

Advances in organ‐on‐a‐chip for the treatment of cardiovascular diseases

MedComm – Biomaterials and Applications, 2023
Cardiovascular disease (CVD) is currently a serious and growing public health problem. In tackling this challenge, organ‐on‐chip (OoC) technology, combined with cell culture and microfluidics, presents a powerful approach for constructing sophisticated ...
Jing Liu, Ying Wang
doaj   +1 more source

Siphon-Controlled Automation on a Lab-on-a-Disc Using Event-Triggered Dissolvable Film Valves

Biosensors, 2021
Within microfluidic technologies, the centrifugal microfluidic “Lab-on-a-Disc” (LoaD) platform offers great potential for use at the PoC and in low-resource settings due to its robustness and the ability to port and miniaturize ‘wet bench’ laboratory ...
Brian D. Henderson, David J. Kinahan, Jeanne Rio, Rohit Mishra, Damien King, Sarai M. Torres-Delgado, Dario Mager, Jan G. Korvink, Jens Ducrée   +8 more
doaj   +1 more source

WAT-on-a-chip: a physiologically relevant microfluidic system incorporating white adipose tissue

, 2022
S.1645-1654Organ-on-a-chip systems possess a promising future as drug screening assays and as testbeds for disease modeling in the context of both single-organ systems and multi-organ-chips.
Zushin, P.J.H., Healy, K.E., Stahl, A., Reese, W.M., Loskill, P., Lee-Montiel, F.T., Jeeawoody, S., Sezhian, T., Tharp, K.M.   +8 more
core   +1 more source

Lab on a Chip Device for Diagnostic Evaluation and Management in Chronic Renal Disease: A Change Promoting Approach in the Patients’ Follow Up

Biosensors, 2023
Lab-on-a-chip (LOC) systems are miniaturized devices aimed to perform one or several analyses, normally carried out in a laboratory setting, on a single chip. LOC systems have a wide application range, including diagnosis and clinical biochemistry.
Margherita Borriello, Giuseppe Tarabella, Pasquale D’Angelo, Aris Liboà, Mario Barra, Davide Vurro, Patrizia Lombari, Annapaola Coppola, Elvira Mazzella, Alessandra F. Perna, Diego Ingrosso   +10 more
doaj   +1 more source

Organ-on-a-chip: a more promising in vitro model [PDF]

Jichu yixue yu linchuang
Traditional in vitro models have inevitable limitations and there are significant differences in assessing drug efficacy and side effects as compared to human trials.
YANG Zhenli, XIA Yujia, LIU Yuqin
doaj   +1 more source

Ultrasensitive optofluidic enzyme-linked immunosorbent assay by on-chip integrated polymer whispering-gallery-mode microlaser sensors [PDF]

, 2023
Optical whispering-gallery-mode (WGM) microcavities offer great promise in ultrasensitive biosensors because of their unique ability to enable resonant recirculation of light to achieve strong light-matter interactions in microscale volumes.
Ouyang, X, Tam, HY, Liu, Tong, Liu, T, Zhang, Y, He, Z, Zhang, Yangxi, Ouyang, Xia, He, Jijun, Zhang, AP, He, Zijian, He, J, Tam, Hwa-Yaw, Zhang, A. Ping   +13 more
core   +1 more source

Microdevice Platform for In Vitro Nervous System and Its Disease Model

Bioengineering, 2017
The development of precise microdevices can be applied to the reconstruction of in vitro human microenvironmental systems with biomimetic physiological conditions that have highly tunable spatial and temporal features.
Jin-Ha Choi, Hyeon-Yeol Cho, Jeong-Woo Choi   +2 more
doaj   +1 more source

Lab-on-a-Chip for Cardiovascular Physiology and Pathology

Micromachines, 2020
Lab-on-a-chip technologies have allowed researchers to acquire a flexible, yet relatively inexpensive testbed to study one of the leading causes of death worldwide, cardiovascular disease.
Sean Beverung, Jingwen Wu, Robert Steward   +2 more
doaj   +1 more source

The tooth on-a-chip: a microphysiologic model system mimicking the biologic interface of the tooth with biomaterials

, 2020
The tooth has a unique configuration with respect to biomaterials that are used for its treatment. Cells inside of the dental pulp interface indirectly with biomaterials via a calcified permeable membrane, formed by the dentin matrix and several ...
Bertassoni, Luiz E., Puppin Rontani, Regina Maria, Sereda, Grigoriy, Franca, Cristiane Miranda, Rodrigues, Nara Sousa, Tahayeri, Anthony, Ferdosian, Shirin, Ferracane, Jack L.   +7 more
core   +1 more source

Contributions of the microbiome to intestinal inflammation in a gut-on-a-chip

Nano Convergence, 2022
The intestinal microbiome affects a number of biological functions of the organism. Although the animal model is a powerful tool to study the relationship between the host and microbe, a physiologically relevant in vitro human intestinal system has still
Min Seo Jeon, Yoon Young Choi, Sung Jun Mo, Jang Ho Ha, Young Seo Lee, Hee Uk Lee, Soo Dong Park, Jae-Jung Shim, Jung-Lyoul Lee, Bong Geun Chung   +9 more
doaj   +1 more source