Results 31 to 40 of about 204,111 (283)

Hyperglycemic Neurovasculature‐On‐A‐Chip to Study the Effect of SIRT1‐Targeted Therapy for the Type 3 Diabetes “Alzheimer's Disease”

Advanced Science, 2022
Diabetes mellitus (DM) is closely related to Alzheimer's disease (AD), but individual cellular changes and the possibilities of recovery through molecular level regulation have not been investigated.
Minjeong Jang, Nakwon Choi, Hong Nam Kim
doaj   +1 more source

Profiling humoral autoimmune repertoire of dilated cardiomyopathy (DCM) patients and development of a disease‐associated protein chip [PDF]

PROTEOMICS, 2006
AbstractDilated cardiomyopathy (DCM) is a myocardial disease characterized by progressive depression of myocardial contractile function and ventricular dilatation. Thirty percent of DCM patients belong to the inherited genetic form; the rest may be idiopathic, viral, autoimmune, or immune‐mediated associated with a viral infection.
Horn, S., Lueking, A., Murphy, D., Staudt, A., Gutjahr, C., Schulte, K., König, A., Landsberger, M., Lehrach, H., Felix, S., Cahill, D.   +10 more
openaire   +3 more sources

Sprayable nanomicelle hydrogels and inflammatory bowel disease patient cell chips for development of intestinal lesion-specific therapy

Bioactive Materials, 2022
All-in-one treatments represent a paradigm shift in future medicine. For example, inflammatory bowel disease (IBD) is mainly diagnosed by endoscopy, which could be applied for not only on-site monitoring but also the intestinal lesion-targeted spray of injectable hydrogels.
Hyo-Jin Yoon, Songhyun Lee, Tae Young Kim, Seung Eun Yu, Hye-Seon Kim, Young Shin Chung, Seyong Chung, Suji Park, Yong Cheol Shin, Eun Kyung Wang, Jihye Noh, Hyun Jung Kim, Cheol Ryong Ku, Hong Koh, Chang-Soo Kim, Joon-Sang Park, Young Min Shin, Hak-Joon Sung   +17 more
openaire   +4 more sources

Advances in organ‐on‐a‐chip for the treatment of cardiovascular diseases

MedComm – Biomaterials and Applications, 2023
Cardiovascular disease (CVD) is currently a serious and growing public health problem. In tackling this challenge, organ‐on‐chip (OoC) technology, combined with cell culture and microfluidics, presents a powerful approach for constructing sophisticated ...
Jing Liu, Ying Wang
doaj   +1 more source

Siphon-Controlled Automation on a Lab-on-a-Disc Using Event-Triggered Dissolvable Film Valves

Biosensors, 2021
Within microfluidic technologies, the centrifugal microfluidic “Lab-on-a-Disc” (LoaD) platform offers great potential for use at the PoC and in low-resource settings due to its robustness and the ability to port and miniaturize ‘wet bench’ laboratory ...
Brian D. Henderson, David J. Kinahan, Jeanne Rio, Rohit Mishra, Damien King, Sarai M. Torres-Delgado, Dario Mager, Jan G. Korvink, Jens Ducrée   +8 more
doaj   +1 more source

Organ-on-a-chip: a more promising in vitro model [PDF]

Jichu yixue yu linchuang
Traditional in vitro models have inevitable limitations and there are significant differences in assessing drug efficacy and side effects as compared to human trials.
YANG Zhenli, XIA Yujia, LIU Yuqin
doaj   +1 more source

A Heart-Breast Cancer-on-a-Chip Platform for Disease Modeling and Monitoring of Cardiotoxicity Induced by Cancer Chemotherapy

Small, 2020
Cardiotoxicity is one of the most serious side effects of cancer chemotherapy. Current approaches to monitoring of chemotherapy-induced cardiotoxicity (CIC) as well as model systems that develop in vivo or in vitro CIC platforms fail to notice early ...
Junmin Lee, Shreya Mehrotra, E. Zare-Eelanjegh, Raquel O. Rodrigues, Alireza Akbarinejad, David Ge, Luca Amato, Kiavash Kiaee, Yongcong Fang, Aliza Rosenkranz, Wendy Keung, B. Mandal, Ronald A. Li, Ting Zhang, HeaYeon Lee, M. Dokmeci, Y. S. Zhang, A. Khademhosseini, S. Shin   +18 more
semanticscholar   +1 more source

Microdevice Platform for In Vitro Nervous System and Its Disease Model

Bioengineering, 2017
The development of precise microdevices can be applied to the reconstruction of in vitro human microenvironmental systems with biomimetic physiological conditions that have highly tunable spatial and temporal features.
Jin-Ha Choi, Hyeon-Yeol Cho, Jeong-Woo Choi   +2 more
doaj   +1 more source

Mobile Efficient Diagnostics of Infectious Diseases via On‐Chip RT‐qPCR: MEDIC‐PCR (Adv. Sci. 28/2023)

Advanced Science, 2023
Mobile Efficient Diagnostics The artwork represents the science behind MEDIC‐PCR, which describes how a rapid photothermal heat cycle by light and carbon black interactions creates the ultrafast photonic PCR. The infrared light emitting diode is illuminated from the bottom on a carbon blackbased PCR chip.
Shrestha, Kiran, Kim, Seongryeong, Han, Jiyeon, Florez, Gabriela Morales, Truong, Han, Hoang, Trung, Parajuli, Sajjan, AM, Tiara, Kim, Beomsoo, Jung, Younsu, Abafogi, Abdurhaman Teyib, Lee, Yugyeong, Song, Seung Hyun, Lee, Jinkee, Park, Sungsu, Kang, Minhee, Huh, Hee Jae, Cho, Gyoujin, Lee, Luke P.   +18 more
openaire   +1 more source

Lab-on-a-Chip for Cardiovascular Physiology and Pathology

Micromachines, 2020
Lab-on-a-chip technologies have allowed researchers to acquire a flexible, yet relatively inexpensive testbed to study one of the leading causes of death worldwide, cardiovascular disease.
Sean Beverung, Jingwen Wu, Robert Steward   +2 more
doaj   +1 more source