Results 31 to 40 of about 195,333 (281)
In Vitro Microfluidic Models for Neurodegenerative Disorders [PDF]
, 2017 Microfluidic devices enable novel means of emulating neurodegenerative disease pathophysiology in vitro. These organ-on-a-chip systems can potentially reduce animal testing and substitute (or augment) simple 2D culture systems. Reconstituting critical
Marco Campisi +4 more
core +1 more source
Profiling humoral autoimmune repertoire of dilated cardiomyopathy (DCM) patients and development of a disease‐associated protein chip [PDF]
PROTEOMICS, 2006 AbstractDilated cardiomyopathy (DCM) is a myocardial disease characterized by progressive depression of myocardial contractile function and ventricular dilatation. Thirty percent of DCM patients belong to the inherited genetic form; the rest may be idiopathic, viral, autoimmune, or immune‐mediated associated with a viral infection.
Horn, S. +10 more
openaire +3 more sources
Microphysiological systems: analysis of the current status, challenges and commercial future [PDF]
, 2018 The field of microphysiological systems (or organs-on-a-chip) experienced, in the past decade, a surge in publications and efforts towards commercialization. Such systems hold the promise to advance drug discovery, diagnostics, and many other areas.
Pawlikowsk, Joanna +2 more
core +3 more sources
Advances in organ‐on‐a‐chip for the treatment of cardiovascular diseases
MedComm – Biomaterials and Applications, 2023 Cardiovascular disease (CVD) is currently a serious and growing public health problem. In tackling this challenge, organ‐on‐chip (OoC) technology, combined with cell culture and microfluidics, presents a powerful approach for constructing sophisticated ...
Jing Liu, Ying Wang
doaj +1 more source
Siphon-Controlled Automation on a Lab-on-a-Disc Using Event-Triggered Dissolvable Film Valves
Biosensors, 2021 Within microfluidic technologies, the centrifugal microfluidic “Lab-on-a-Disc” (LoaD) platform offers great potential for use at the PoC and in low-resource settings due to its robustness and the ability to port and miniaturize ‘wet bench’ laboratory ...
Brian D. Henderson +8 more
doaj +1 more source
Organ-on-a-chip: a more promising in vitro model [PDF]
Jichu yixue yu linchuangTraditional in vitro models have inevitable limitations and there are significant differences in assessing drug efficacy and side effects as compared to human trials.
YANG Zhenli, XIA Yujia, LIU Yuqin
doaj +1 more source
Biosensors, 2023 Lab-on-a-chip (LOC) systems are miniaturized devices aimed to perform one or several analyses, normally carried out in a laboratory setting, on a single chip. LOC systems have a wide application range, including diagnosis and clinical biochemistry.
Margherita Borriello +10 more
doaj +1 more source
Microdevice Platform for In Vitro Nervous System and Its Disease Model
Bioengineering, 2017 The development of precise microdevices can be applied to the reconstruction of in vitro human microenvironmental systems with biomimetic physiological conditions that have highly tunable spatial and temporal features.
Jin-Ha Choi +2 more
doaj +1 more source
Lab-on-a-Chip for Cardiovascular Physiology and Pathology
Micromachines, 2020 Lab-on-a-chip technologies have allowed researchers to acquire a flexible, yet relatively inexpensive testbed to study one of the leading causes of death worldwide, cardiovascular disease.
Sean Beverung +2 more
doaj +1 more source
Frontiers in microfluidics, a teaching resource review [PDF]
, 2019 This is a literature teaching resource review for biologically inspired microfluidics courses or exploring the diverse applications of microfluidics. The structure is around key papers and model organisms.
Merrin, Jack
core +2 more sources