Results 21 to 30 of about 207,508 (246)
Aggregate, 2023 Organ‐on‐a‐chip (OOC) platforms recapitulate human in vivo‐like conditions more realistically compared to many animal models and conventional two‐dimensional cell cultures.
Sajjad Rahmani Dabbagh +5 more
doaj +1 more source
Towards establishing human body-on-a-chip systems
Stem Cell Research & Therapy, 2022 Body-on-a-chip (BoC) platforms are established from multiple organs-on-chips (OoCs) to recapitulate the interactions between different tissues. Recently, Vunjak-Novakovic and colleagues reported the creation of a BoC system comprising four fluidically ...
Zhong Alan Li, Rocky S. Tuan
doaj +1 more source
Corrigendum to "Toxicity and absorption of polystyrene micro-nanoplastics in healthy and Crohn's disease human duodenum-chip models" [J Hazard Mater 490 (2025) 137714]. [PDF]
J Hazard MaterKharaghani D +10 more
europepmc +2 more sources
Alveolus Lung-on-a-Chip Platform: A Proposal
Chemosensors, 2021 Respiratory diseases are top-ranked causes of deaths and disabilities around the world, making new approaches to the treatment necessary. In recent years, lung-on-a-chip platforms have emerged as a potential candidate to replace animal experiments ...
Noelia Campillo +2 more
doaj +1 more source
Disease-on-a-chip: mimicry of tumor growth in mammary ducts [PDF]
Lab Chip, 2014 We present a disease-on-a-chip model in which cancer grows within phenotypically normal breast luminal epithelium on semicircular acrylic support mimicking portions of mammary ducts. The cells from tumor nodules developing within these hemichannels are morphologically distinct from their counterparts cultured on flat surfaces.
Vidi, Pierre-Alexandre +6 more
openaire +3 more sources
Mobile Efficient Diagnostics of Infectious Diseases via On‐Chip RT‐qPCR: MEDIC‐PCR
Advanced Science, 2023 AbstractThe COVID‐19 outbreak has caused public and global health crises. However, the lack of on‐site fast, reliable, sensitive, and low‐cost reverse transcription polymerase chain reaction (RT‐PCR) testing limits early detection, timely isolation, and epidemic prevention and control.
Kiran Shrestha +18 more
openaire +3 more sources
Construction of diagnostic markers for hub lncRNAs in Parkinson’s disease based on chip re-annotation [PDF]
, 2021 Abstract BACKGROUND Parkinson’s disease (PD) is a progressive neurodegenerative disease that is also the most common motor disorder and is accompanied by the loss of DA neurons in the brain. Long non-coding RNAs (lncRNAs) have recently been identified as new genetic entities that regulate cellular processes.
Yi Quan +3 more
openaire +1 more source
Advanced Science, 2022 Diabetes mellitus (DM) is closely related to Alzheimer's disease (AD), but individual cellular changes and the possibilities of recovery through molecular level regulation have not been investigated.
Minjeong Jang, Nakwon Choi, Hong Nam Kim
doaj +1 more source
Microfluidic Organ-on-a-Chip System for Disease Modeling and Drug Development
Biosensors, 2022 An organ-on-a-chip is a device that combines micro-manufacturing and tissue engineering to replicate the critical physiological environment and functions of the human organs.
Zening Li +3 more
doaj +1 more source
Profiling humoral autoimmune repertoire of dilated cardiomyopathy (DCM) patients and development of a disease‐associated protein chip [PDF]
PROTEOMICS, 2006 AbstractDilated cardiomyopathy (DCM) is a myocardial disease characterized by progressive depression of myocardial contractile function and ventricular dilatation. Thirty percent of DCM patients belong to the inherited genetic form; the rest may be idiopathic, viral, autoimmune, or immune‐mediated associated with a viral infection.
Horn, S. +10 more
openaire +3 more sources