Results 11 to 20 of about 92,114,249 (286)

An Immune Microenvironment-Integrated Intestinal-on-a-Chip Model for Investigating Immunopathogenesis in Inflammatory Bowel Disease [PDF]

Molecules
Owing to the multifactorial nature of inflammatory bowel disease (IBD) pathogenesis, conventional two-dimensional (2D) models inadequately recapitulate the complex in vivo microenvironment.
Shiyang Ying, Huanhua Xu, Yi Xu, Xianqiang Mi   +3 more
doaj   +2 more sources

Lab-on-a-Chip Platforms for Detection of Cardiovascular Disease and Cancer Biomarkers

Sensors, 2017
Cardiovascular disease (CVD) and cancer are two leading causes of death worldwide. CVD and cancer share risk factors such as obesity and diabetes mellitus and have common diagnostic biomarkers such as interleukin-6 and C-reactive protein.
Jiandong Wu, Meili Dong, Susy Santos, Claudio Rigatto, Yong Liu, Francis Lin   +5 more
doaj   +3 more sources

Glioma-on-a-Chip Models

Micromachines, 2021
Glioma, as an aggressive type of cancer, accounts for virtually 80% of malignant brain tumors. Despite advances in therapeutic approaches, the long-term survival of glioma patients is poor (it is usually fatal within 12–14 months).
Merve Ustun, Sajjad Rahmani Dabbagh, Irem Sultan Ilci, Tugba Bagci-Onder, Savas Tasoglu   +4 more
doaj   +1 more source

Corrigendum to "Attenuation of blood-brain barrier dysfunction by functionalized gold nanoparticles against amyloid-β peptide in an Alzheimer's disease-on-a-chip model" [Mater. Today Bio 35 (2025) 102453]. [PDF]

Mater Today Bio
Arellano A, Palma-Florez S, Cabrera P, Cortés-Adasme E, Bolaños K, Celis F, Araya-Vergara AJ, Pérez M, Crespo A, Matus MH, Araya E, Aldunate R, Kogan MJ, Samitier J, Lagunas A, Mir M, Hassan N.   +16 more
europepmc   +3 more sources

From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC) [PDF]

, 2020
We present a portable, battery-operated and application-specific lab-on-a-chip (ASLOC) system that can be easily configured for a wide range of lab-on-a-chip applications. It is based on multiplexed electrical current detection that serves as the sensing
Campos, C. D. M., Manz, A., Soon, J. B. W., Neužil, P., Reboud, J., Wong, C. C.   +5 more
core   +2 more sources

Sistemas microfisiológicos compostos por organoides humanos em dispositivos microfluídicos: avanços e desafios

Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2018
Introdução: Modelos com maior capacidade preditiva e que produzam resultados a custos mais baixos e em prazos menores são necessários para o desenvolvimento de fármacos. Os sistemas microfisiológicos (SMF) que cultivam tecidos humanos em histoarquitetura
Talita Miguel Marin, Eduardo Pagani
doaj   +7 more sources

Corrigendum to "Toxicity and absorption of polystyrene micro-nanoplastics in healthy and Crohn's disease human duodenum-chip models" [J Hazard Mater 490 (2025) 137714]. [PDF]

J Hazard Mater
Kharaghani D, DeLoid GM, He P, Swenor B, Bui TH, Zuverza-Mena N, Tamez C, Musante C, Verzi M, White JC, Demokritou P.   +10 more
europepmc   +2 more sources

3D bioprinted organ‐on‐chips

Aggregate, 2023
Organ‐on‐a‐chip (OOC) platforms recapitulate human in vivo‐like conditions more realistically compared to many animal models and conventional two‐dimensional cell cultures.
Sajjad Rahmani Dabbagh, Misagh Rezapour Sarabi, Mehmet Tugrul Birtek, Nur Mustafaoglu, Yu Shrike Zhang, Savas Tasoglu   +5 more
doaj   +1 more source

Disease-on-a-chip: mimicry of tumor growth in mammary ducts [PDF]

Lab Chip, 2014
We present a disease-on-a-chip model in which cancer grows within phenotypically normal breast luminal epithelium on semicircular acrylic support mimicking portions of mammary ducts. The cells from tumor nodules developing within these hemichannels are morphologically distinct from their counterparts cultured on flat surfaces.
Vidi, Pierre-Alexandre, Maleki, Teimour, Ochoa, Manuel, Wang, Lei, Clark, Sara M., Leary, James F., Lelievre, Sophie A.   +6 more
openaire   +3 more sources

Towards establishing human body-on-a-chip systems

Stem Cell Research & Therapy, 2022
Body-on-a-chip (BoC) platforms are established from multiple organs-on-chips (OoCs) to recapitulate the interactions between different tissues. Recently, Vunjak-Novakovic and colleagues reported the creation of a BoC system comprising four fluidically ...
Zhong Alan Li, Rocky S. Tuan
doaj   +1 more source