Results 11 to 20 of about 195,333 (281)

Sistemas microfisiológicos compostos por organoides humanos em dispositivos microfluídicos: avanços e desafios [PDF]

Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2018
Introdução: Modelos com maior capacidade preditiva e que produzam resultados a custos mais baixos e em prazos menores são necessários para o desenvolvimento de fármacos. Os sistemas microfisiológicos (SMF) que cultivam tecidos humanos em histoarquitetura
Talita Miguel Marin, Eduardo Pagani
doaj   +11 more sources

Lab-on-a-Chip Platforms for Detection of Cardiovascular Disease and Cancer Biomarkers

Sensors, 2017
Cardiovascular disease (CVD) and cancer are two leading causes of death worldwide. CVD and cancer share risk factors such as obesity and diabetes mellitus and have common diagnostic biomarkers such as interleukin-6 and C-reactive protein.
Jiandong Wu, Meili Dong, Susy Santos, Claudio Rigatto, Yong Liu, Francis Lin   +5 more
doaj   +3 more sources

Microengineering the Liver: Strategies for Constructing Functional Liver‐on‐a‐Chip Devices [PDF]

Exploration
Reliable in vitro liver models are indispensable for researching liver diseases and developing medications. Present 2D/3D cell cultures and animal models inadequately replicate the intricacy of living systems and in vivo conditions, resulting in impaired
Jie Wang, Ziwei Liang, Jiapu Wang, Zongyi Li, Shaojie Wang, Yan Wei, Xin Xie, Di Huang   +7 more
doaj   +2 more sources

Glioma-on-a-Chip Models

Micromachines, 2021
Glioma, as an aggressive type of cancer, accounts for virtually 80% of malignant brain tumors. Despite advances in therapeutic approaches, the long-term survival of glioma patients is poor (it is usually fatal within 12–14 months).
Merve Ustun, Sajjad Rahmani Dabbagh, Irem Sultan Ilci, Tugba Bagci-Onder, Savas Tasoglu   +4 more
doaj   +1 more source

Corrigendum to "Attenuation of blood-brain barrier dysfunction by functionalized gold nanoparticles against amyloid-β peptide in an Alzheimer's disease-on-a-chip model" [Mater. Today Bio 35 (2025) 102453]. [PDF]

Mater Today Bio
Arellano A, Palma-Florez S, Cabrera P, Cortés-Adasme E, Bolaños K, Celis F, Araya-Vergara AJ, Pérez M, Crespo A, Matus MH, Araya E, Aldunate R, Kogan MJ, Samitier J, Lagunas A, Mir M, Hassan N.   +16 more
europepmc   +3 more sources

Bioinspired NEMS-Prospective of Collaboration with Nature [PDF]

, 2022
The fields of micro- and nanomechanics are strongly interconnected with the development of micro-electro-mechanical (MEMS) and nano-electro-mechanical (NEMS) devices, their fabrication and applications.
Bokić, Bojana, Kolarić, Branko, Simović-Pavlović, Marina, Vasiljević, Darko   +3 more
core   +4 more sources

Corrigendum to "Toxicity and absorption of polystyrene micro-nanoplastics in healthy and Crohn's disease human duodenum-chip models" [J Hazard Mater 490 (2025) 137714]. [PDF]

J Hazard Mater
Kharaghani D, DeLoid GM, He P, Swenor B, Bui TH, Zuverza-Mena N, Tamez C, Musante C, Verzi M, White JC, Demokritou P.   +10 more
europepmc   +2 more sources

3D bioprinted organ‐on‐chips

Aggregate, 2023
Organ‐on‐a‐chip (OOC) platforms recapitulate human in vivo‐like conditions more realistically compared to many animal models and conventional two‐dimensional cell cultures.
Sajjad Rahmani Dabbagh, Misagh Rezapour Sarabi, Mehmet Tugrul Birtek, Nur Mustafaoglu, Yu Shrike Zhang, Savas Tasoglu   +5 more
doaj   +1 more source

Microfluidic Platforms to Unravel Mysteries of Alzheimer's Disease: How Far Have We Come? [PDF]

, 2021
Alzheimer’s disease (AD) is a significant health concern with enormous social and economic impact globally. The gradual deterioration of cognitive functions and irreversible neuronal losses are primary features of the disease.
Chandra Goud, Macherla Sharath, Gupta, Piyush Kumar, Hawthorne, Susan, Jha, Niraj Kumar, Jha, Saurabh Kumar, Mandal, Debabrata, Ojha, Shreesh, Prasanna, Pragya, Rahul, Vedanabhatla, Rathee, Shweta, Sharma, Ankur, Villa, Chiara, Yadav, Pardeep   +12 more
core   +3 more sources

Induced pluripotent stem cell-based organ-on-a-chip as personalized drug screening tools: A focus on neurodegenerative disorders [PDF]

, 2022
The Organ-on-a-Chip (OoC) technology shows great potential to revolutionize the drugs development pipeline by mimicking the physiological environment and functions of human organs.
Albani D., Campanile M., Fanizza F., Forloni G., Giordano C.   +4 more
core   +4 more sources