Results 11 to 20 of about 12,664,100 (362)

Lyme Disease Pathogenesis. [PDF]

Current Issues in Molecular Biology, 2020
Lyme disease Borrelia are obligately parasitic, tick- transmitted, invasive, persistent bacterial pathogens that cause disease in humans and non-reservoir vertebrates primarily through the induction of inflammation.
J. Coburn, B. Garcia, Linden T. Hu, Mollie W. Jewett, P. Kraiczy, S. Norris, J. Skare   +6 more
semanticscholar   +4 more sources

Pathogenesis of autoimmune disease

Nature Reviews Nephrology, 2023
Autoimmune diseases are a diverse group of conditions characterized by aberrant B cell and T cell reactivity to normal constituents of the host. These diseases occur widely and affect individuals of all ages, especially women.
D. Pisetsky
semanticscholar   +3 more sources

Pathogenesis of Alzheimer’s Disease

International Journal of Molecular Sciences, 2022
Alzheimer's disease (AD) is the most common type of dementia, accounting for 60% to 80% of all cases [...].
A. Rostagno
semanticscholar   +3 more sources

Inflammatory bowel disease: pathogenesis.

World Journal of Gastroenterology, 2014
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is characterized by chronic relapsing intestinal inflammation. It has been a worldwide health-care problem with a continually increasing incidence. It is thought that IBD
Yizhe Zhang, Yong-yu Li
semanticscholar   +3 more sources

The pathogenesis of Parkinson's disease

Lancet, The

semanticscholar   +3 more sources

Bilobalide Exerts Anti-Inflammatory Effects on Chondrocytes Through the AMPK/SIRT1/mTOR Pathway to Attenuate ACLT-Induced Post-Traumatic Osteoarthritis in Rats

Frontiers in Pharmacology, 2022
Although osteoarthritis (OA) significantly affects the quality of life of the elderly, there is still no effective treatment strategy. The standardized Ginkgo biloba L.
Tianwen Ma, Tianwen Ma, Liangyu Lv, Liangyu Lv, Yue Yu, Yue Yu, Lina Jia, Lina Jia, Xiaopeng Song, Xiaopeng Song, XinYu Xu, XinYu Xu, Ting Li, Ting Li, Xuanbo Sheng, Xuanbo Sheng, Haoran Wang, Haoran Wang, Jiantao Zhang, Jiantao Zhang, Li Gao, Li Gao   +21 more
doaj   +1 more source

Microglia in Alzheimer’s disease: pathogenesis, mechanisms, and therapeutic potentials

Frontiers in Aging Neuroscience, 2023
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by protein aggregation in the brain. Recent studies have revealed the critical role of microglia in AD pathogenesis.
Jifei Miao, Hai-Yang Ma, Yang Yang, Y. Liao, Cui-ting Lin, J. Zheng, Muli Yu, Jiao Lan   +7 more
semanticscholar   +1 more source

Dark-light cycle disrupts bone metabolism and suppresses joint deterioration in osteoarthritic rats

Arthritis Research & Therapy, 2022
Background Light alteration affects the internal environment and metabolic homeostasis of the body through circadian rhythm disorders (CRD). CRD is one of the factors that induce and accelerate osteoarthritis (OA). Therefore, the aim of this study was to
Xiaopeng Song, Mingchao Zhao, Jilang Tang, Tianwen Ma, Hui Bai, Xinyu Wang, Lin Liu, Ting Li, Xinyu Xu, Xuanbo Sheng, Binger Zhao, Yingying Wang, Tiantian Wang, Yingchao Guo, Xinmin Zhang, Li Gao   +15 more
doaj   +1 more source

Circ_0006944 aggravates LPS-induced HK2 cell injury via modulating miR-205-5p/UBL4A pathway

Autoimmunity, 2023
Circular RNAs (circRNAs) has been manifested to be involved in the development of human diseases, including sepsis-associated acute kidney injury (SA-AKI).
Fan Zhou, Dong Liu, Junwei Ye, Bingqi Li
doaj   +1 more source

Pathogenesis of Crohn's disease [PDF]

F1000Prime Reports, 2015
Significant progress in our understanding of Crohn's disease (CD), an archetypal common, complex disease, has now been achieved. Our ability to interrogate the deep complexities of the biological processes involved in maintaining gut mucosal homeostasis is a major over-riding factor underpinning this rapid progress. Key studies now offer many novel and
Boyapati, Ray, Satsangi, Jack, Ho, Gwo-Tzer   +2 more
openaire   +3 more sources