Results 11 to 20 of about 6,660,576 (307)

Pathogenesis of Parkinson's disease [PDF]

open access: yesCurrent opinion in neurology and neurosurgery, 1992
The importance of genetic aspects, ageing, environmental factors, head trauma, defective mitochondrial respiration, altered iron metabolism, oxidative stress and glutamatergic overactivity of the basal ganglia in the pathogenesis of Parkinson's disease ...
Riederer, Peter, Lange, Klaus W.
core   +3 more sources

The pathogenesis of Parkinson's disease [PDF]

open access: yesThe Lancet
Parkinson's disease is a progressive neurodegenerative condition associated with the deposition of aggregated α-synuclein. Insights into the pathogenesis of Parkinson's disease have been derived from genetics and molecular pathology. Biochemical studies,
Williams-Gray, Caroline H   +3 more
core   +5 more sources

Lyme Disease Pathogenesis [PDF]

open access: yesCurrent Issues in Molecular Biology, 2021
Lyme disease Borrelia are obligately parasitic, tick- transmitted, invasive, persistent bacterial pathogens that cause disease in humans and non-reservoir vertebrates primarily through the induction of inflammation. During transmission from the infected tick, the bacteria undergo significant changes in gene expression, resulting in adaptation to the ...
Garcia, Brandon   +6 more
openaire   +3 more sources

Eosinophils and Disease Pathogenesis [PDF]

open access: yesSeminars in Hematology, 2012
Eosinophils are granulocytic innate immune cells whose presence is conspicuous in a variety of disease states, including eosinophilic hyperproliferative and infiltrative processes, as well as conditions associated with maladaptive Th2 inflammation.
Akuthota, Praveen, Weller, Peter
openaire   +4 more sources

Pathogenesis of chronic obstructive pulmonary disease [PDF]

open access: yes, 2005
The current paradigm for the pathogenesis of chronic obstructive pulmonary disease is that chronic airflow limitation results from an abnormal inflammatory response to inhaled particles and gases in the lung. Airspace inflammation appears to be different
Macnee, W
core   +1 more source

Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease. [PDF]

open access: yes, 2009
Cerebral malaria is a life-threatening complication of malaria infection. The pathogenesis of cerebral malaria is poorly defined and progress in understanding the condition is severely hampered by the inability to study in detail, ante-mortem, the ...
KEVIN N. COUPER   +11 more
core   +1 more source

Health-Related Quality of Life in Inflammatory Bowel Disease [PDF]

open access: yes, 2012
This book is dedicated to inflammatory bowel disease, and the authors discuss the advances in the pathogenesis of inflammatory bowel disease, as well as several new parameters involved in the etiopathogeny of Crohn's disease and ulcerative colitis, such ...
Ramiro Verissimo
core   +2 more sources

Age-dependent differences in the pathogenesis of bovine respiratory syncytial virus infections related to the development of natural immunocompetence [PDF]

open access: yes, 2010
The severity of respiratory syncytial virus (RSV) infections appears to differ with age in both humans and bovines. A primary RSV infection in naïve infants and in young calves runs a more severe course when they are 1–6 months old than in their first ...
Most, R.G., van der   +6 more
core   +1 more source

Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition

open access: yesScientific Reports, 2017
Our recent studies revealed that supplementation with the reduced form of coenzyme Q10 (CoQ10H2) inhibits oxidative stress and slows the process of aging in senescence-accelerated mice.
Zhe Xu   +10 more
doaj   +1 more source

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