Results 31 to 40 of about 12,664,100 (362)

Endoplasmic reticulum stress mediated by ROS participates in cadmium exposure-induced MC3T3-E1 cell apoptosis

open access: yesEcotoxicology and Environmental Safety, 2023
Cadmium (Cd), as one of the seventh most toxic heavy metal pollutants, widely persisted in the environment, leading to osteoblast dysfunction and ultimately Cd-related skeletal disease.
Lina Jia   +6 more
doaj   +1 more source

Acinetobacter baumannii Biofilm Formation and Its Role in Disease Pathogenesis: A Review

open access: yesInfection and Drug Resistance, 2021
Acinetobacter species, particularly Acinetobacter baumannii, is the first pathogen on the critical priority list of pathogens for novel antibiotics to become a “red-alert” human pathogen. Acinetobacter baumannii is an emerging global antibiotic-resistant
A. Gedefie   +7 more
semanticscholar   +1 more source

Babesia duncani in Culture and in Mouse (ICIM) Model for the Advancement of Babesia Biology, Pathogenesis and Therapy

open access: yesBio-Protocol, 2022
Babesiosis is a tick-borne disease caused by pathogens belonging to the genus Babesia. In humans, the disease presents as a malaria-like illness and can be fatal in immunocompromised and elderly people.
Vandana Kumari   +3 more
doaj   +1 more source

piRNAs as Modulators of Disease Pathogenesis

open access: yesInternational Journal of Molecular Sciences, 2021
Advances in understanding disease pathogenesis correlates to modifications in gene expression within different tissues and organ systems. In depth knowledge about the dysregulation of gene expression profiles is fundamental to fully uncover mechanisms in
K. Rayford   +9 more
semanticscholar   +1 more source

Multi-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis.

open access: yesCirculation Research, 2021
Calcific aortic valve disease sits at the confluence of multiple world-wide epidemics of aging, obesity, diabetes, and renal dysfunction, and its prevalence is expected to nearly triple over the next 3 decades.
M. Blaser   +3 more
semanticscholar   +1 more source

Columnaris disease in fish: a review with emphasis on bacterium-host interactions [PDF]

open access: yes, 2013
Flavobacterium columnare (F. columnare) is the causative agent of columnaris disease. This bacterium affects both cultured and wild freshwater fish including many susceptible commercially important fish species. F. columnare infections may result in skin
Bossier, Peter   +4 more
core   +3 more sources

CALM1 promotes progression and dampens chemosensitivity to EGFR inhibitor in esophageal squamous cell carcinoma

open access: yesCancer Cell International, 2021
Background Calmodulin1 (CALM1) has been identified as one of the overexpression genes in a variety of cancers and EGFR inhibitor have been widely used in clinical treatment but it is unknown whether CALM1 and epidermal growth factor receptor (EGFR) have ...
Tao Liu   +7 more
doaj   +1 more source

Huntington’s Disease Pathogenesis: Two Sequential Components

open access: yesJournal of Huntington's Disease, 2021
Historically, Huntington’s disease (HD; OMIM #143100) has played an important role in the enormous advances in human genetics seen over the past four decades.
E. Hong   +10 more
semanticscholar   +1 more source

Current concept on the pathogenesis of inflammatory bowel disease-crosstalk between genetic and microbial factors: Pathogenic bacteria and altered bacterial sensing or changes in mucosal integrity take "toll"? [PDF]

open access: yes, 2006
The pathogenesis of inflammatory bowel disease (IBD) is only partially understood. Various environmental and host (e.g. genetic-, epithelial-, immune and non-immune) factors are involved.
Fischer, Simon   +4 more
core   +1 more source

Breaking Bad: Inflammasome Activation by Respiratory Viruses

open access: yesBiology, 2023
The nucleotide-binding domain leucine-rich repeat-containing receptor (NLR) family is a group of intracellular sensors activated in response to harmful stimuli, such as invading pathogens.
Julia A. Cerato   +2 more
doaj   +1 more source

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