Results 31 to 40 of about 6,660,576 (307)

Exosomes and miRNAs in disease pathogenesis and opportunities for molecular targeting [PDF]

, 2016
Exosomes/extracellular vesicles (EVs) are cell-derived mixed-populations of vesicles released by almost all cells into the intercellular microenvironment, ending up in the circulation.
Momen Heravi, F.
core   +1 more source

Current concept on the pathogenesis of inflammatory bowel disease-crosstalk between genetic and microbial factors: Pathogenic bacteria and altered bacterial sensing or changes in mucosal integrity take "toll"? [PDF]

, 2006
The pathogenesis of inflammatory bowel disease (IBD) is only partially understood. Various environmental and host (e.g. genetic-, epithelial-, immune and non-immune) factors are involved.
Papp, János, Lakatos, Péter László, Fischer, Simon, Lakatos, László, Gál, István   +4 more
core   +1 more source

Pathogenesis of Alzheimer’s Disease

International Journal of Molecular Sciences, 2022
Alzheimer’s disease (AD) is the most common type of dementia, accounting for 60% to 80% of all cases [...]
openaire   +2 more sources

Evolving Mechanisms in the Pathophysiology of Pemphigus Vulgaris: A Review Emphasizing the Role of Desmoglein 3 in Regulating p53 and the Yes-Associated Protein

Life, 2021
The immunobullous condition Pemphigus Vulgaris (PV) is caused by autoantibodies targeting the adhesion proteins of desmosomes, leading to blistering in the skin and mucosal membrane.
Ambreen Rehman, Yunying Huang, Hong Wan
doaj   +1 more source

Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice [PDF]

, 2010
Dengue virus (DENV), a mosquito-borne flavivirus, is a public health problem in many tropical countries. Recent clinical data have shown an association between levels of different chemokines in plasma and severity of dengue.
Mauro M Teixeira, Besnard, Anne-Gaëlle, Danielle G Souza, Fagundes, C.T., Teixeira, Mauro M, Guabiraba Rodrigo, Fagundes Caio T., Teixeira Mauro M., Anne-Gaëlle Besnard, Souza, Danielle G., Souza Danielle G., Danielle G. Souza, Mauro M. Teixeira, Teixeira, M.M., Caio T Fagundes, Ryffel Bernhard, Bernhard Ryffel, Souza, Danielle G, Besnard, A., Marques, Rafael Elias, Fagundes, Caio T., Ryffel, Bernhard, Rodrigo Guabiraba, Fagundes, Caio T, Marques Rafael Elias, Marques, R.E., Guabiraba, Rodrigo, Guabiraba Brito, R., Besnard Anne-Gaëlle, Rafael Elias Marques, Caio T. Fagundes   +30 more
core   +2 more sources

Exercise training based on individual physical fitness and interval walking training to prevent lifestyle-related diseases in middle-aged and older people

Journal of Physical Fitness and Sports Medicine, 2012
Physical inactivity contributes to type II diabetes, cardiovascular disease, depression, dementia, and cancer, defined as the “diseasome of physical inactivity”; however, there is no exercise training regimen broadly available in the field to prevent ...
Hiroshi Nose, Mayuko Morikawa, Shizue Masuki, Ken Miyagawa, Yoshi-ichiro Kamijo, Hirokazu Gen-no   +5 more
doaj   +1 more source

Pathogenesis and prevention of immune reconstitution disease during antiretroviral therapy. [PDF]

, 2011
The risks of unmasking and paradoxical forms of immune reconstitution disease in HIV-infected patients starting antiretroviral therapy (ART) are fuelled by a combination of the late presentation of patients with advanced immunodeficiency, the associated ...
Lawn, Stephen D, Meintjes, Graeme, Graeme Meintjes, Stephen D Lawn   +3 more
core   +1 more source

Pathogenesis of Alzheimer disease

Vojnosanitetski pregled, 2007
<zakljucak> Alchajmerova bolest javlja se kod 50-60% svih dementnih osoba i predstavlja znacajan zdravstveni i socijalni problem. Upoznavanje patogeneze AB je neophodno u nalazenju terapija koje bi ublazile i modifikovale bolest. Najvise dokaza ima za hipotezu o amiloidnoj kaskadi.
Pavlović Dragan M., Pavlović Aleksandra M., Žugić Stana   +2 more
openaire   +3 more sources

Heterogeneity across mammalian- and avian-origin A(H1N1) influenza viruses influences viral infectivity following incubation with host bacteria from the human respiratory tract

Microbiology Spectrum
Influenza A viruses (IAVs) are primarily transmitted between mammals by the respiratory route and encounter bacteria in the respiratory tract before infecting susceptible epithelial cells. Previous studies have shown that mammalian-origin IAV can bind to
Poulami Basu Thakur, Hannah A. Bullock, James Stevens, Amrita Kumar, Taronna R. Maines, Jessica A. Belser   +5 more
doaj   +1 more source

The Interrelated Multifactorial Actions of Cortisol and Klotho: Potential Implications in the Pathogenesis of Parkinson’s Disease [PDF]

, 2022
The pathogenesis of Parkinson's disease (PD) is complex, multilayered, and not fully understood, resulting in a lack of effective disease-modifying treatments for this prevalent neurodegenerative condition.
Clow, A., Corcos, D.M., Luthra, N.S., Clow, Angela, Luthra, Nijee S., Nijee S. Luthra, Angela Clow, Daniel M. Corcos, Corcos, Daniel M.   +8 more
core   +1 more source