Results 21 to 30 of about 6,660,576 (307)

Realization of Amyloid-like Aggregation as a Common Cause for Pathogenesis in Diseases

Life, 2023
Amyloids were conventionally referred to as extracellular and intracellular accumulation of Aβ42 peptide, which causes the formation of plaques and neurofibrillary tangles inside the brain leading to the pathogenesis in Alzheimer’s disease. Subsequently,
Soumick Naskar, Nidhi Gour
doaj   +1 more source

Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY. [PDF]

, 2010
The unparalleled collection of clinical data and biomaterials within the EHDN's REGISTRY can expedite the search for disease modifiers (genetic and environmental) of age at onset and disease progression that could be harnessed for the development of ...
Handley, Olivia J, Landwehrmeyer, G Bernhard, Aileen K Ho, Bisson, Jonathan Ian, Schwenke C, David Craufurd, Dunnett, Stephen B., Handley, Olivia, Investigators of the European Huntington's Disease Network, The, DI MARIA, EMILIO, Craufurd D, Dunnett, SB, Carsten Schwenke, the investigators of the European Huntington's Disease Network, Craufurd, David, Edward Wild, Landwehrmeyer, GB, Busse, Monica, Rosser, Anne Elizabeth, Olivia J Handley, Romano Silvia., Tabrizi SJ, Ho, Aileen K., Wild, E, Landwehrmeyer GB, Craufurd, D, Tabrizi, SJ, Tabrizi, Sarah J., Handley, OJ, Rickards, Hugh, Dunnett, Stephen, Ho, Aileen K, Orth, Michael, Ho, AK, Wild, Edward, Stephen B. Dunnett, Sarah J Tabrizi, Wild, EJ, Landwehrmeyer, G. Bernhard, Naji, Jenny, Landwehrmeyer, G. Bernhard, Wild E, Investigators of the European Huntington's Disease Network, Handley, Olivia J., Orth, M, Ellison-Rose, Lynda, Tabrizi, Sarah J, Price, Kathleen, Ho AK, ABBRUZZESE, GIOVANNI, Schwenke, C, Ho, A, Orth M, Handley OJ, Schwenke, Carsten, Dunnett SB, Dunnett, Stephen B, Michael Orth, G. Bernhard Landwehrmeyer   +59 more
core   +1 more source

Pathogenesis of autoimmune disease

Nature Reviews Nephrology, 2023
Autoimmune diseases are a diverse group of conditions characterized by aberrant B cell and T cell reactivity to normal constituents of the host. These diseases occur widely and affect individuals of all ages, especially women. Among these diseases, the most prominent immunological manifestation is the production of autoantibodies, which provide ...
openaire   +2 more sources

Extracellular Vesicles in Acute Leukemia: A Mesmerizing Journey With a Focus on Transferred microRNAs

Frontiers in Cell and Developmental Biology, 2021
Despite their small size, the membrane-bound particles named extracellular vesicles (EVs) seem to play an enormous role in the pathogenesis of acute leukemia.
Mehrdad Izadirad, Zoufang Huang, Farideh Jafari, Amir Ali Hamidieh, Ahmad Gharehbaghian, Yi-Dong Li, Leila Jafari, Zhe-Sheng Chen, Zhe-Sheng Chen   +8 more
doaj   +1 more source

Pathogenesis of Kawasaki disease

Clinical and Experimental Immunology, 2011
Summary Kawasaki disease (KD) most frequently affects infants and young children under 5 years of age. This disease is considered a kind of systemic vasculitis syndrome, and primarily invades the medium-sized muscular arteries, including coronary arteries.
K, Takahashi, T, Oharaseki, Y, Yokouchi
openaire   +3 more sources

Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK

Molecules, 2023
Luteoloside has shown anti-inflammatory, antiviral, and antitumor properties. However, the effect and mechanism of luteoloside on neuroblastoma cells remain unknown.
Ya He, Maohong Luo, Shan Lei, Zhirui Zeng, Tengxiang Chen, Yingmin Wu, Dongyan Wang, Long Wang, Lu Wang   +8 more
doaj   +1 more source

TSE pathogenesis in cattle and sheep [PDF]

, 2008
Many studies have been undertaken in rodents to study the pathogenesis of transmissible spongiform encephalopathies (TSE). Only a few studies have focused on the pathogenesis of bovine spongiform encephalopathy (BSE) and scrapie in their natural hosts ...
Bossers, A., Fred van Zijderveld, Lucien J.M. van Keulen, Keulen, L.J.M., van, Zijderveld, F.G., van, Bossers, Alex, Alex Bossers, Van Zijderveld, Fred, Van Keulen, Lucien   +8 more
core   +1 more source

Dengue. [PDF]

, 2010
INTRODUCTION: Dengue is a vector-borne viral infection that endangers an estimated 2.5 billion people. Disease caused by dengue ranges from a relatively minor febrile illness to a life-threatening condition characterized by extensive capillary leak.
Whitehorn, Jamie, Farrar, Jeremy, J. Whitehorn, J. Farrar, Whitehorn, James   +4 more
core   +1 more source

Sensor Sensibility—HIV-1 and the Innate Immune Response

Cells, 2020
Innate immunity represents the human immune system’s first line of defense against a pathogenic intruder and is initiated by the recognition of conserved molecular structures known as pathogen-associated molecular patterns (PAMPs) by specialized ...
Xin Yin, Simon Langer, Zeli Zhang, Kristina M. Herbert, Sunnie Yoh, Renate König, Sumit K. Chanda   +6 more
doaj   +1 more source

Pathogenesis of Crohn's disease [PDF]

F1000Prime Reports, 2015
Significant progress in our understanding of Crohn's disease (CD), an archetypal common, complex disease, has now been achieved. Our ability to interrogate the deep complexities of the biological processes involved in maintaining gut mucosal homeostasis is a major over-riding factor underpinning this rapid progress. Key studies now offer many novel and
Boyapati, Ray, Satsangi, Jack, Ho, Gwo-Tzer   +2 more
openaire   +2 more sources