Results 91 to 100 of about 8,964,528 (267)

Dietary fiber-driven shifts in mycobiota and short-chain fatty acid landscape in porcine hindgut

Animal Microbiome
This study employed a porcine model to investigate the dynamic effects of inulin (INU) and microcrystalline cellulose (MCC) on the profiles of intestinal short-chain fatty acids (SCFAs) and the composition of rectal fungal communities.
Jianwei Qin, Hua Li, Xiaofeng Deng, Shuangmei Huang, Jun He, Aimin Wu, Zhaolai Dai, Jingyi Cai, Gang Tian, Xiangbing Mao, Bing Yu, Ping Zheng, Junqiu Luo, Hui Yan, Jiayong Tang, Yuheng Luo   +15 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Molecular Screening of Pea Germplasm for Rust Disease Resistance using SSR Marker

, 2017
In order to determine the association of molecular markers with the pea rust resistance, thirty two diverse pea genotypes were phenotypically screened on the basis of disease reaction followed by molecular screening using four SSR markers - AA446 and ...
K.P.S. Kushwaha, KPS Kushwaha, Vinod Upadhyay, Puja Pandey   +3 more
core   +1 more source

Post-transport recovery trajectory of the canine gut microbiome and metabolome

Journal of Animal Science and Biotechnology
Background Transportation induces a multisystem stress response in companion animals, yet the integrated recovery dynamics across physiological, microbial, and metabolic domains remain poorly characterized.
Yang Lyu, Chunxia Su, Keying Sun, Yuwei Wang, Lingna Zhang, Junning Pu, Caimei Wu, David Thomas, Lianqiang Che   +8 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Purine Metabolism and Hexosamine Biosynthetic Pathway Abnormalities in Diarrheal Weaned Piglets Identified Using Metabolomics

Animals
Post-weaning diarrhea significantly contributes to the high mortality in pig production, but the metabolic changes in weaned piglets with diarrhea remain unclear.
Mingyu Wang, Qin Zhong, Huailu Xin, Bing Yu, Jun He, Jie Yu, Xiangbing Mao, Zhiqing Huang, Yuheng Luo, Junqiu Luo, Hui Yan, Aimin Wu, Junning Pu, Ping Zheng   +13 more
doaj   +1 more source

Effects of Corn Naturally Contaminated with Aflatoxins on Performance, Calcium and Phosphorus Metabolism, and Bone Mineralization of Broiler Chicks

The Journal of Poultry Science, 2014
The objective of this study was to investigate the effects of corn naturally contaminated with low levels of aflatoxins (AF) on performance, calcium (Ca) and phosphorus (P) metabolism, and bone mineralization in broilers.
Shiping Bai, Leilei Wang, Yuheng Luo, Xumei Ding, Jun Yang, Jie Bai, Keying Zhang, Jianping Wang   +7 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The Ncm-1 gene for resistance to Cucumber mosaic virus in yellow lupin (Lupinus luteus): molecular studies and marker development [PDF]

, 2012
Cucumber mosaic virus (CMV) is an important virus pathogen of lupins in Australia which causes serious yield losses of up to 60% in epidemic years. In commercially grown lupin (Lupinus angustifolius and L.
Li, Dora
core