Results 21 to 30 of about 8,435 (234)

Synthesis of 3,4-Bis(Butylselanyl)Selenophenes and 4-Alkoxyselenophenes Promoted by Oxone^®

Molecules, 2021
We describe herein an alternative transition-metal-free procedure to access 3,4-bis(butylselanyl)selenophenes and the so far unprecedented 3-(butylselanyl)-4-alkoxyselenophenes. The protocol involves the 5-endo-dig electrophilic cyclization of 1,3-diynes
Paola S. Hellwig, Jonatan S. Guedes, Angelita M. Barcellos, Gelson Perin, Eder J. Lenardão   +4 more
doaj   +1 more source

Diselenides and Benzisoselenazolones as Antiproliferative Agents and Glutathione-S-Transferase Inhibitors

Molecules, 2019
A series of variously functionalized selenium-containing compounds were purposely synthesized and evaluated against a panel of cancer cell lines. Most of the compounds showed an interesting cytotoxicity profile with compound 5 showing a potent activity ...
Dorota Krasowska, Nunzio Iraci, Claudio Santi, Józef Drabowicz, Marcin Cieslak, Julia Kaźmierczak-Barańska, Martina Palomba, Karolina Królewska-Golińska, Jakub Magiera, Luca Sancineto   +9 more
doaj   +1 more source

Targeted Delivery of Chlorin e6 via Redox Sensitive Diselenide-Containing Micelles for Improved Photodynamic Therapy in Cluster of Differentiation 44-Overexpressing Breast Cancer

Frontiers in Pharmacology, 2019
The off-target activation of photosensitizers is one of the most well-known obstacles to effective photodynamic therapy (PDT). The selected activation of photosensitizers in cancer cells is highly desired to overcome this problem. We developed a strategy
Chan Feng, Donglei Zhu, Lv Chen, Yonglin Lu, Jie Liu, Na Yoon Kim, Shujing Liang, Xia Zhang, Yun Lin, Yabin Ma, Chunyan Dong   +10 more
doaj   +1 more source

Organic Passivation of Deep Defects in Cu(In,Ga)Se2 Film for Geometry-Simplified Compound Solar Cells

Research, 2023
Diverse defects in copper indium gallium diselenide solar cells cause nonradiative recombination losses and impair device performance. Here, an organic passivation scheme for surface and grain boundary defects is reported, which employs an organic ...
Jingwei Chen, Xuan Chang, Jianxin Guo, Qing Gao, Xuning Zhang, Chenxu Liu, Xueliang Yang, Xin Zhou, Bingbing Chen, Feng Li, Jianming Wang, Xiaobing Yan, Dengyuan Song, Han Li, Benjamin S. Flavel, Shufang Wang, Jianhui Chen   +16 more
doaj   +1 more source

Integration of a Diselenide Unit Generates Fluorogenic Camptothecin Prodrugs with Improved Cytotoxicity to Cancer Cells

, 2021
A diselenide/disulfide unit was introduced into camptothecin (CPT), and two selenoprodrugs (e.g., CPT–Se3 and CPT–Se4) were identified to show improved potency in killing cancer cells and inhibiting tumor growth in vivo.
Jintao Zhao (10309677), Jianguo Fang (1375440), Qianhe Xu, Bingbing Chang, Xinming Li, Bingbing Chang (3624476), Miao Zhong, Xinming Li (143063), Zihua Wang, Jintao Zhao, Miao Zhong (313963), Qianhe Xu (6387377), Jianguo Fang, Zihua Wang (290751)   +13 more
core   +2 more sources

Crystal structures of 4,4′-(disulfane-1,2-diyl)bis(5-methyl-2H-1,3-dithiol-2-one) and 4,4′-(diselanane-1,2-diyl)bis(5-methyl-2H-1,3-dithiol-2-one)

Acta Crystallographica Section E: Crystallographic Communications, 2018
The two title compounds, C8H6O2S6 and C8H6O2S4Se2, are isotypic with very similar cell parameters. The complete molecules constitute the asymmetric units, despite being chemically perfectly symmetric.
Ivan Trentin, Claudia Schindler, Carola Schulzke   +2 more
doaj   +1 more source

Diselenide Crosslinks for Enhanced and Simplified Oxidative Protein Folding

, 2020
The oxidative folding of proteins has been studied for over sixty years, providing critical insight into protein folding mechanisms. A well-known folding model for many disulfide-rich proteins is that of hirudin.
Lareen, Khouri, Deborah E., Shalev, Shifra, Lansky, Reem, Mousa, Sergei, Pomyalov, Taghreed, Hidmi, Gil, Shoham, Norman, Metanis   +7 more
core   +1 more source

In Vitro Activity of Ebselen and Diphenyl Diselenide Alone and in Combination with Drugs against Trichophyton mentagrophytes Strains

Pharmaceutics, 2022
Background: Dermatophytoses are one of the most prevalent infectious diseases in the world for which the pace of developing new drugs has not kept pace with the observed therapeutic problems.
Sebastian Gnat, Dominik Łagowski, Mariusz Dyląg, Grzegorz Jóźwiak, Aleksandra Trościańczyk, Aneta Nowakiewicz   +5 more
doaj   +1 more source

Terahertz generation from surface of the bulk and monolayer tungsten diselenide

Российский технологический журнал, 2020
The study of ultrafast laser interaction with graphene-like materials based on transition metal dichalcogenides attracts most scientific groups. It is connected with potential use of these materials in flexible optoelectronic devices of visible and THz ...
D. I. Khusyainov, A. V. Gorbatova, A. M. Buryakov   +2 more
doaj   +1 more source

Reduction of Diphenyl Diselenide and Analogs by Mammalian Thioredoxin Reductase Is Independent of Their Gluthathione Peroxidase-Like Activity: A Possible Novel Pathway for Their Antioxidant Activity

Molecules, 2010
Since the successful use of the organoselenium drug ebselen in clinical trials for the treatment of neuropathological conditions associated with oxidative stress, there have been concerted efforts geared towards understanding the precise mechanism of ...
João Batista Teixeira Rocha, Diego Alves, Lisiane Oliveira Porciúncula, Jéssie Haigert Sudati, Caroline Wagner, Andressa Sausen de Freitas, Alessandro de Souza Prestes, Ige Joseph Kade   +7 more
doaj   +1 more source