Results 11 to 20 of about 689,915 (161)

Selenoprotein K form an intermolecular diselenide bond with unusually high redox potential [PDF]

open access: yesFEBS Letters, 2014
Selenoprotein K (SelK) is a membrane protein involved in antioxidant defense, calcium regulation and the ER-associated protein degradation pathway. We found that SelK exhibits a peroxidase activity with a rate that is low but within the range of other ...
Sharon Rozovsky
exaly   +4 more sources

Structural reorganization and crack-healing properties of hydrogels based on dynamic diselenide linkages

open access: yesScience and Technology of Advanced Materials, 2020
We report the dynamic behavior of diselenide-containing hydrophilic polyurethanes and hydrogels based on diselenide exchange reactions in an aqueous media.
Hao Xu   +6 more
doaj   +2 more sources

Precision Oncology via Radiotherapy-Triggered Drug Delivery: Mechanisms, Molecular Engineering, and Clinical Translation. [PDF]

open access: yesAdv Sci (Weinh)
This review redefines radiotherapy‐triggered drug delivery systems through structural disassembly and molecular actuation, proposing a translation‐oriented framework for dose‐correlated activation to advance clinically integrated precision oncology. ABSTRACT Radiotherapy‐triggered drug delivery systems (RDDS) promise to integrate the spatial precision ...
Jiang J, Zhang T, Dong J, Sun W.
europepmc   +2 more sources

Diselenide-Bridged Doxorubicin Dimeric Prodrug: Synthesis and Redox-Triggered Drug Release

open access: yesMolecules
The diselenide bond has attracted intense interest in redox-responsive drug delivery systems (DDSs) in tumor chemotherapy, due to its higher sensitivity than the most investigated bond, namely the disulfide bond.
Yanru Hu, Peng Liu
doaj   +3 more sources

Synthesis of 3,4-Bis(Butylselanyl)Selenophenes and 4-Alkoxyselenophenes Promoted by Oxone®

open access: yesMolecules, 2021
We describe herein an alternative transition-metal-free procedure to access 3,4-bis(butylselanyl)selenophenes and the so far unprecedented 3-(butylselanyl)-4-alkoxyselenophenes. The protocol involves the 5-endo-dig electrophilic cyclization of 1,3-diynes
Paola S. Hellwig   +4 more
doaj   +1 more source

Visible Light-Induced Templated Metathesis of Peptide–Nucleic Acid Conjugates with a Diselenide Bridge

open access: yesBiomolecules, 2023
The use of template molecules as chemical scaffolds that significantly influence the course of the reaction has recently been intensively studied. Peptide nucleic acids (PNA) are molecules that mimic natural nucleic acids.
Mateusz Waliczek   +4 more
doaj   +1 more source

Selenium-functionalized polycarbonate-polyurethane for sustained in situ generation of therapeutic gas for blood-contacting materials

open access: yesSmart Materials in Medicine, 2022
Polyurethanes (PU) have been widely used in blood-contacting devices including indwelling implants and extracorporeal devices due to its good biocompatibility.
Peichuang Li   +7 more
doaj   +1 more source

Clarification on the Reactivity of Diaryl Diselenides toward Hexacyclohexyldilead under Light

open access: yesMolecules, 2021
In this study, the reactivity of organochalcogen compounds toward a representative alkyl-lead bond compound under light was investigated in detail.
Vu Thai Hung   +5 more
doaj   +1 more source

Teaching @ Bond

open access: yes, 2011
Teaching at Bond has been written specifically for teachers at Bond University. It contains usefule information to induct teachers into their teaching role at Bond University, provide affirmation teaching strategies as a Bond teacher, and help enhance ...
Kinash, Shelley
core   +4 more sources

Regio- and Stereoselective Synthesis of (Z,Z)-Bis(3-amino-3-oxo-1-propenyl) Selenides and Diselenides Based on 2-propynamides: A Novel Family of Diselenides with High Glutathione Peroxidase-like Activity

open access: yesInorganics, 2022
The efficient regio- and stereoselective syntheses of (Z,Z)-bis(3-amino-3-oxo-1-propenyl) selenides and diselenides in high yields based on the nucleophilic addition of sodium selenide to 2-propynamides and sodium diselenide to 3-(trimethylsilyl)-2 ...
Vladimir A. Potapov   +5 more
doaj   +1 more source

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