Catalytic Antioxidant Activity of Bis-Aniline-Derived Diselenides as GPx Mimics
Molecules, 2021 Herein, we describe a simple and efficient route to access aniline-derived diselenides and evaluate their antioxidant/GPx-mimetic properties. The diselenides were obtained in good yields via ipso-substitution/reduction from the readily available 2 ...
Giancarlo V Botteselle +2 more
exaly +3 more sources
The Influence of Long Carbon Chains on the Antioxidant and Anticancer Properties of N-Substituted Benzisoselenazolones and Corresponding Diselenides [PDF]
Pharmaceuticals, 2023 Organoselenium compounds are well-known for their numerous biocapacities, which result from the uniqueness of the selenium atom and the possibility of constructing heterorganic molecules that can mimic the activity of selenoenzymes, crucial for a ...
Agata J. Pacuła-Miszewska +5 more
doaj +2 more sources
Selenides and Diselenides: A Review of Their Anticancer and Chemopreventive Activity
Molecules, 2018 Selenium and selenocompounds have attracted the attention and the efforts of scientists worldwide due to their promising potential applications in cancer prevention and/or treatment.
Mónica Alvarez-Perez +2 more
exaly +3 more sources
Electrochemical Synthesis of 3-Selenyl-Chromones via Domino C(sp2)-H Bond Selenylation/Annulation of Enaminones [PDF]
MoleculesHerein, we disclose a highly efficient pathway toward 3-selenylated chromone derivatives via electrosynthesis domino C(sp2)-H bond selenylation/cyclization/deamination of 2-hydroxyaryl enaminones with diselenides. This method showed mild conditions, easy
João M. Brito +12 more
doaj +2 more sources
Synthesis and Biological Evaluation of 2-Picolylamide-Based Diselenides with Non-Bonded Interactions
Molecules, 2015 In this paper, we report the synthesis and biological evaluation of picolylamide-based diselenides with the aim of developing a new series of diselenides with O···Se non-bonded interactions.
Jamal Rafique +2 more
exaly +3 more sources
Glutathione Peroxidase-like Activities of Oxygen-Containing Diselenides
Molecules, 1998 Various diselenides 1 – 8 have been examined with respect to their glutathione peroxidase-like activities (GPx-activities) as an index of their antioxidant properties.
Thomas Wirth, Wirth Thomas
exaly +3 more sources
The Chemistry of Selenosilanes: A Topic Overview [PDF]
MoleculesSelenium-containing molecules represent a valuable class of compounds with a variety of applications in chemical and biological fields. Selenated reagents are used as intermediates to introduce functional groups (e.g., double bonds) onto different ...
Damiano Tanini, Antonella Capperucci
doaj +2 more sources
Recent Advances in the Use of Diorganyl Diselenides as Versatile Catalysts [PDF]
Molecules, 2023 The importance of organoselenium compounds has been increasing in synthetic chemistry. These reagents are well-known as electrophiles and nucleophiles in many organic transformations, and in recent years, their functionality as catalysts has also been ...
Gabriel Pereira da Costa +3 more
doaj +2 more sources
Bismuth(III)-Catalyzed Regioselective Selenation of Indoles with Diaryl Diselenides: Synthesis of 3-Selanylindoles [PDF]
MoleculesHeterocyclic aryl selenides have recently attracted considerable research interest owing to their applications in biological and pharmaceutical fields. Herein, we describe a simple and general synthesis of 3-selanylindoles via a novel regioselective C–H ...
Mio Matsumura +5 more
doaj +2 more sources
Ultrasound-promoted synthesis of 2-organoselanyl-naphthalenes using Oxone® in aqueous medium as an oxidizing agent [PDF]
PeerJ, 2018 A green methodology to synthesize 2-organoselanyl-naphthalenes based on the reaction of alkynols with diaryl diselenides is described. The electrophilic species of selenium were generated in situ, by the oxidative cleavage of the Se–Se bond of diaryl ...
Gelson Perin +6 more
doaj +2 more sources