Results 1 to 10 of about 2,174 (182)

Catalytic Antioxidant Activity of Bis-Aniline-Derived Diselenides as GPx Mimics [PDF]

Molecules, 2021
Herein, we describe a simple and efficient route to access aniline-derived diselenides and evaluate their antioxidant/GPx-mimetic properties. The diselenides were obtained in good yields via ipso-substitution/reduction from the readily available 2 ...
Gianluca Ciancaleoni, Giancarlo V Botteselle, Antonio Braga   +2 more
exaly   +5 more sources

Selenides and Diselenides: A Review of Their Anticancer and Chemopreventive Activity

Molecules, 2018
Selenium and selenocompounds have attracted the attention and the efforts of scientists worldwide due to their promising potential applications in cancer prevention and/or treatment.
Mónica Alvarez-Perez, Wesam Ali, Jadwiga Handzlik   +2 more
exaly   +3 more sources

Synthesis and Biological Evaluation of 2-Picolylamide-Based Diselenides with Non-Bonded Interactions

Molecules, 2015
In this paper, we report the synthesis and biological evaluation of picolylamide-based diselenides with the aim of developing a new series of diselenides with O···Se non-bonded interactions.
Antonio Braga, Romulo Faria Santos Canto, Jamal Rafique   +2 more
exaly   +3 more sources

Glutathione Peroxidase-like Activities of Oxygen-Containing Diselenides

Molecules, 1998
Various diselenides 1 – 8 have been examined with respect to their glutathione peroxidase-like activities (GPx-activities) as an index of their antioxidant properties.
Thomas Wirth
exaly   +3 more sources

Electrochemical Synthesis of 3-Selenyl-Chromones via Domino C(sp²)-H Bond Selenylation/Annulation of Enaminones [PDF]

Molecules
Herein, we disclose a highly efficient pathway toward 3-selenylated chromone derivatives via electrosynthesis domino C(sp2)-H bond selenylation/cyclization/deamination of 2-hydroxyaryl enaminones with diselenides. This method showed mild conditions, easy
João M. Brito, Isabella M. e Oliveira, Cassio A. O. Moraes, Alex R. Schneider, Tiago E. A. Frizon, Giancarlo V. Botteselle, Vijay P. Singh, André L. Stein, Gleison A. Casagrande, Giuseppe A. Camara, Antonio L. Braga, Jamal Rafique, Sumbal Saba   +12 more
doaj   +2 more sources

The Chemistry of Selenosilanes: A Topic Overview [PDF]

Molecules
Selenium-containing molecules represent a valuable class of compounds with a variety of applications in chemical and biological fields. Selenated reagents are used as intermediates to introduce functional groups (e.g., double bonds) onto different ...
Damiano Tanini, Antonella Capperucci
doaj   +2 more sources

Bismuth(III)-Catalyzed Regioselective Selenation of Indoles with Diaryl Diselenides: Synthesis of 3-Selanylindoles [PDF]

Molecules
Heterocyclic aryl selenides have recently attracted considerable research interest owing to their applications in biological and pharmaceutical fields. Herein, we describe a simple and general synthesis of 3-selanylindoles via a novel regioselective C–H ...
Mio Matsumura, Airi Umeda, Yuika Sumi, Naoki Aiba, Yuki Murata, Shuji Yasuike   +5 more
doaj   +2 more sources

Ultrasound-promoted synthesis of 2-organoselanyl-naphthalenes using Oxone® in aqueous medium as an oxidizing agent [PDF]

PeerJ, 2018
A green methodology to synthesize 2-organoselanyl-naphthalenes based on the reaction of alkynols with diaryl diselenides is described. The electrophilic species of selenium were generated in situ, by the oxidative cleavage of the Se–Se bond of diaryl ...
Gelson Perin, Daniela Rodrigues Araujo, Patrick Carvalho Nobre, Eder João Lenardao, Raquel Guimarães Jacob, Marcio Santos Silva, Juliano Alex Roehrs   +6 more
doaj   +2 more sources

Regio- and Stereoselective Synthesis of (Z,Z)-Bis(3-amino-3-oxo-1-propenyl) Selenides and Diselenides Based on 2-propynamides: A Novel Family of Diselenides with High Glutathione Peroxidase-like Activity

Inorganics, 2022
The efficient regio- and stereoselective syntheses of (Z,Z)-bis(3-amino-3-oxo-1-propenyl) selenides and diselenides in high yields based on the nucleophilic addition of sodium selenide to 2-propynamides and sodium diselenide to 3-(trimethylsilyl)-2 ...
Vladimir A. Potapov, Mikhail V. Andreev, Maxim V. Musalov, Irina V. Sterkhova, Svetlana V. Amosova, Lyudmila I. Larina   +5 more
doaj   +1 more source

Synthesis and anticancer activity of bis(2-arylimidazo[1,2-a]pyridin-3-yl) selenides and diselenides: the copper-catalyzed tandem C–H selenation of 2-arylimidazo[1,2-a]pyridine with selenium

Beilstein Journal of Organic Chemistry, 2020
Most heteroaryl selenides and diselenides are biologically active, with some reported to act as antioxidants and show activities that are medicinally relevant; hence, the development of efficient methods for their synthesis is an important objective ...
Mio Matsumura, Tsutomu Takahashi, Hikari Yamauchi, Shunsuke Sakuma, Yukako Hayashi, Tadashi Hyodo, Tohru Obata, Kentaro Yamaguchi, Yasuyuki Fujiwara, Shuji Yasuike   +9 more
doaj   +1 more source