Nectin4‐targeted molecular imaging in solid tumors: Current status and future perspectives
VIEW, Volume 6, Issue 3, June 2025.In this review, we provide a concise overview of the mechanisms by which Nectin4 contributes to the pathogenesis of various malignancies and detail the classes of Nectin4‐targeted molecular probes. We then delve into the significant advancements in Nectin4‐targeted molecular imaging techniques, encompassing both nuclear medicine and optical imaging ...
Yongshun Liu +6 more
wiley +1 more source
Brain-enriched Hyaluronan Binding (BEHAB)/Brevican Cleavage in a Glioma Cell Line Is Mediated by a Disintegrin and Metalloproteinase with Thrombospondin Motifs (ADAMTS) Family Member [PDF]
, 2000 Russell T. Matthews +6 more
openalex +1 more source
International Journal of Rheumatic Diseases, Volume 28, Issue 6, June 2025.ABSTRACT Introduction This study examined the efficacy and safety of Rituximab (RTX) treatment in connective tissue disease (CTD)‐associated thrombocytopenic purpura (TTP) and thrombotic microangiopathy (TMA), using historical controls as comparators.
Naoaki Ohkubo +7 more
wiley +1 more source
A Novel Snake Venom Disintegrin That Inhibits Human Ovarian Cancer Dissemination and Angiogenesis in an Orthotopic Nude Mouse Model [PDF]
, 2001 Francis S. Markland +6 more
openalex +1 more source
Healthy Aging Metabolomic and Proteomic Signatures Across Multiple Physiological Compartments
Aging Cell, Volume 24, Issue 6, June 2025.The association of the aging scores with the clinical covariates suggests increased inflammation, strong predisposition to iron deficiency anemia, decline in muscle mass, and renal and hepatic functions with accelerated aging. ABSTRACT The study of biomarkers in biofluids and tissues expanded our understanding of the biological processes that drive ...
R. Moaddel +17 more
wiley +1 more source
Metalloprotease-disintegrin ADAM 12 interacts with α-actinin-1 [PDF]
, 2001 Yi Cao, Qing Kang, Anna Żółkiewska
openalex +1 more source
Molecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
SorCS2 Is Important for Astrocytic Function in Neurovascular Signaling
Acta Physiologica, Volume 241, Issue 6, June 2025.ABSTRACT Introduction The receptor SorCS2 is involved in the trafficking of membrane receptors and transporters. It has been implicated in brain disorders and has previously been reported to be indispensable for ionotropic glutamatergic neurotransmission in the hippocampus.
Christian Staehr +14 more
wiley +1 more source
A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model [PDF]
, 2004 Rolf Postina
openalex +3 more sources
In vivo regulation of the A disintegrin and metalloproteinase 10 (ADAM10) by the tetraspanin 15
Cellular and Molecular Life Sciences, 2018 Lisa Seipold +10 more
semanticscholar +1 more source