Results 81 to 90 of about 2,933,555 (304)
Clinics in Perinatology, 2014 Electrolyte disorders can result in life-threatening complications. The kidneys are tasked with maintaining electrolyte homoeostasis, yet the low glomerular filtration rate of neonatal kidneys, tubular immaturity, and high extrarenal fluid losses contribute to increased occurrence of electrolyte disorders in neonates.
Bockenhauer, D, Zieg, J
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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International Journal of Bipolar DisordersBackground Mitochondrial dysfunction is implicated in the neuropathology of bipolar disorder (BD). Higher circulating cell-free mitochondrial DNA (ccf-mtDNA), generally reflecting poorer mitochondrial health, has been associated with greater symptoms ...
Suyi Shao +8 more
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Diagnosis of Body Dysmorphic Disorder
, 2015 Body dysmorphic disorder (BDD) is characterized by an excessive preoccupation with one or more perceived defects in appearance that are not observable or appear only as minor to others.
Katlein França +5 more
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BMC PsychiatryBackground The human brain is a dynamic neural system with time-varying functional connectivity (FC) strengths between brain regions. Evidence indicates that adolescents with major depressive disorder (MDD) exhibit decreased average FC strength in ...
Tongxin Li +9 more
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A Novel Dual-Frequency Deep Brain Stimulation Paradigm for Parkinson’s Disease
Neurology and Therapy, 2019 Introduction Deep brain stimulation (DBS) of the subthalamic nucleus (STN) using high-frequency (130–185 Hz) stimulation (HFS) is more effective for appendicular than for axial symptoms.
Jessica A. Karl +2 more
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Disorder! Disorder! Disorder! [PDF]
Acta Crystallographica Section A Foundations and Advances, 2017 Christine M. Beavers +1 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
jd-coderepos/disorder-normalizer:
, 2022 A system for normalizing disorder mentions in biomedical ...
jennydsuza9
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