Results 11 to 20 of about 1,947 (193)

Strain-Release Driven Epoxidation and Aziridination of Bicyclo[1.1.0]butanes via Palladium Catalyzed σ-Bond Nucleopalladation. [PDF]

Angew Chem Weinheim Bergstr Ger, 2023
Strained spirocyclic epoxides and aziridines were synthesized via three‐component coupling between in situ generated 1‐lithio bicyclo [1.1.0]butane, a broad variety of ketones, aldehydes and N‐tosyl imines, and aryl triflates. The key step involves a highly diastereoselective palladium‐catalyzed C−C σ‐bond alkoxyarylation (or aminoarylation) of bicyclo
Wölfl B, Winter N, Li J, Noble A, Aggarwal VK.   +4 more
europepmc   +4 more sources

Semisynthesis of Novel Dispiro-pyrrolizidino/thiopyrrolizidino-oxindolo/indanedione Natural Product Hybrids of Parthenin Followed by Their Cytotoxicity Evaluation [PDF]

ACS Omega, 2023
Chetan Paul Singh, Priyanka Sharma, Manzoor Ahmed, Diljeet Kumar, Yogesh Brijwashi Sharma, Jayanta Samanta, Zabeer Ahmed, Sanket Kumar Shukla, Abhijit Hazra, Yogesh P. Bharitkar   +9 more
doaj   +2 more sources

Synthesis, Topological, and Biological Studies of a Novel One-Dimensional Hg(II) Coordination Polymer With Antibacterial and Anticancer Potentials. [PDF]

Bioinorg Chem Appl
A novel one‐dimensional mercury coordination polymer (CP), identified as [(μ2‐Cl)(Ina)Hg(μ3‐Cl)Hg(μ2‐Cl)2(Ina)]n (1) (where Ina represents isonicotinic acid or 4‐pyridinecarboxylic acid), was synthesized via the interaction of isonicotinic acid with mercury(II) salt.
Alaei S, Mohammadi K, Hayati P, Gharibi S, Khoradmehr A, Asen Z, Janczak J, Alexandrov EV.   +7 more
europepmc   +2 more sources

7,8,15,16-tetraoxa-dispiro[5.2.5.2]hexadecane-3-carboxylic acid derivatives and their antimalarial activity [PDF]

Journal of the Serbian Chemical Society, 2004
Several C2 symmetrical mixed tetraoxanes were prepared starting from a gemdihydroperoxide and a ketone. The obtained tetraoxanes showed pronounced antimalarial activity against P. falciparum chloroquine resistant W2 and chloroquine susceptible D6 strains,
BOGDAN SOLAJA, WILBUR K. MILHOUS, DEJAN OPSENICA, NATASA TERZIC, IGOR OPSENICA   +4 more
doaj   +3 more sources

Stereoselective Synthesis of a Novel Series of Dispiro-oxindolopyrrolizidines Embodying Thiazolo[3,2-a]benzimidazole Motif: A Molecular Electron Density Theory Study of the Mechanism of the [3 + 2] Cycloaddition Reaction

Chemistry, 2023
A one-pot multi-component reaction was employed for the stereoselective synthesis of a novel set of dispiro-oxindolopyrrolizidines analogs incorporating a thiazolo[3,2-a]benzimidazole scaffold based on the [3 + 2] cycloaddition (32CA) reaction approach ...
Assem Barakat, Saeed Alshahrani, Abdullah Mohammed Al-Majid, Abdullah Saleh Alamary, M. Ali, Mar Ríos-Gutiérrez   +5 more
doaj   +1 more source

Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani [PDF]

, 2020
A chemically diverse range of novel tetraoxanes was synthesized and evaluated in vitro against intramacrophage amastigote forms of Leishmania donovani. All 15 tested tetraoxanes displayed activity, with IC50 values ranging from 2 to 45 µm.
Amado, Patrícia, Cabral, Lília, Cojean, Sandrine, Cristiano, Maria De Lurdes, Loiseau, Philippe M., Pomel, Sébastien   +5 more
core   +1 more source

Cyclotrimerization Approach to Symmetric [9]Helical Indenofluorenes: Diverting Cyclization Pathways

Chemistry – A European Journal, Volume 29, Issue 58, October 18, 2023., 2023
Catalytic cyclotrimerization (Rh, Co, and Ni catalysts) of triyne 1 gives rise preferentially to [9]helical indenofluorene, whereas it thermal cyclization gives rise to polyaromatic hydrocarbon 3. The former reaction proceeds via classical alkyne cyclotrimerization, the latter via dehydro‐Diels–Alder reaction accompanied by unusual C−C cleavage.
Timothée Cadart, Tim Gläsel, Ivana Císařová, Róbert Gyepes, David Nečas, Marko Hapke, Martin Kotora   +6 more
wiley   +1 more source

Bifunctional thiourea-catalyzed asymmetric [3 + 2] annulation reactions of 2-isothiocyanato-1-indanones with barbiturate-based olefins

Beilstein Journal of Organic Chemistry, 2022
Bifunctional thiourea-catalyzed asymmetric [3 + 2] annulation reactions of 2-isothiocyanato-1-indanones with barbiturate-based olefins have been developed to afford chiral dispiro[indene-pyrrolidine-pyrimidine]s.
Jiang-Song Zhai, Da-Ming Du
doaj   +1 more source

Recent Advances in Multicomponent Electro‐Organic (Electrochemical) Synthesis of Heterocycles

Asian Journal of Organic Chemistry, Volume 12, Issue 8, August 2023., 2023
This review provides a summary of electrosynthesis methods that can be used as an alternative method for synthesis of complex organic molecules in pharmaceutical and biological applications. This method involves electro‐organic reactions occurring at room temperature and normal pressure through transferring electrons.
Sahar Imeni, Ata Makarem, Ramin Javahershenas   +2 more
wiley   +1 more source

Kinetically Stabilized Diarylpnictogenium Ions

ChemPlusChem, Volume 88, Issue 3, March 2023., 2023
The preparation and full characterization of the stibenium and bismuthenium ions completes the series of kinetically stabilized heavier pnictogenium ions [RindMesE]+ (E=P, As Sb, Bi). The different colours of the species within this series were attributed to energy differences of the LUMOs. Comparison with the bis(m‐terphenyl)‐substituted stibenium and
Marvin Janssen, Stefan Mebs, Jens Beckmann   +2 more
wiley   +1 more source