Results 21 to 30 of about 1,879 (233)

Strain-Release Driven Epoxidation and Aziridination of Bicyclo[1.1.0]butanes via Palladium Catalyzed σ-Bond Nucleopalladation. [PDF]

Angew Chem Weinheim Bergstr Ger, 2023
Strained spirocyclic epoxides and aziridines were synthesized via three‐component coupling between in situ generated 1‐lithio bicyclo [1.1.0]butane, a broad variety of ketones, aldehydes and N‐tosyl imines, and aryl triflates. The key step involves a highly diastereoselective palladium‐catalyzed C−C σ‐bond alkoxyarylation (or aminoarylation) of bicyclo
Wölfl B, Winter N, Li J, Noble A, Aggarwal VK.   +4 more
europepmc   +4 more sources

The structure and antimalarial activity of dispiro-1,2,4,5-tetraoxanes derived from (+)-dihydrocarvone

Bioorganic & Medicinal Chemistry Letters, 2010
An unsaturated dispiro 1,2,4,5-tetraoxane formed by peroxidation of (+)-dihydrocarvone was converted into four structurally diverse derivatives. X-ray crystallographic analysis shows that the structures possess central tetraoxane rings with spiro-2,5-disubstituted cyclohexylidene substituents and 6-membered rings in classical chair conformations.
Dong, Y., McCullough, K. J., Wittlin, S., Chollet, J., Vennerstrom, J. L.   +4 more
openaire   +3 more sources

Synthesis, Structures, and Optical Properties of Heteroarene-Fused Dispiro Compounds

, 2016
Novel heteroarene-fused dispiro compounds, dispiro[9H-fluorene-9,5′(6′H)-diindeno[1,2-b:2′,1′-d]furan-6′,9′′-[9H]fluorene] (dsp-DIF), dispiro[9H-fluorene-9,5′(6′H)-diindeno[1,2-b:2′,1′-d]thiophene-6′,9′′-[9H]fluorene] (dsp-DIT), and 11-phenyldispiro[9H ...
Toshiyuki Kowada (2149042), Kouichi Ohe (1470874), Toshihisa Kuwabara (2320897)   +2 more
core   +4 more sources

Synthesis, Topological, and Biological Studies of a Novel One-Dimensional Hg(II) Coordination Polymer With Antibacterial and Anticancer Potentials. [PDF]

Bioinorg Chem Appl
A novel one‐dimensional mercury coordination polymer (CP), identified as [(μ2‐Cl)(Ina)Hg(μ3‐Cl)Hg(μ2‐Cl)2(Ina)]n (1) (where Ina represents isonicotinic acid or 4‐pyridinecarboxylic acid), was synthesized via the interaction of isonicotinic acid with mercury(II) salt.
Alaei S, Mohammadi K, Hayati P, Gharibi S, Khoradmehr A, Asen Z, Janczak J, Alexandrov EV.   +7 more
europepmc   +2 more sources

New Dispiro Compounds:  Synthesis and Properties

, 2016
We report the synthesis and structural characterization of two dispiro compounds. These two positional isomers have been designed and synthesized through an efficient method.
Joëlle Rault-Berthelot (2455918), Alexandra M. Z. Slawin (809268), Cyril Poriel (1520128), Frédéric Barrière (2455915)   +3 more
core   +4 more sources

Tautomerism troubles: proton transfer modifies the stereochemical assignments in diastereoisomeric structures of spirocyclic 5-methyl-2H-imidazol-4-amine dimers

Acta Crystallographica Section E: Crystallographic Communications, 2021
During the racemization of a novel pharmaceutical spirocyclic imidazole–amine compound, namely, 6′-bromo-N-(6′-bromo-4-methoxy-4′′-methyl-3′H-dispiro[cyclohexane-1,2′-indene-1′,2′′-imidazol]-5′′-yl)-4-methoxy-4′′-methyl-3′H-dispiro[cyclohexane-1,2 ...
Helen Blade, Peter N. Horton, James A. Morrison, James B. Orton, Rachel A. Sullivan, Simon J. Coles   +5 more
doaj   +1 more source

Bifunctional thiourea-catalyzed asymmetric [3 + 2] annulation reactions of 2-isothiocyanato-1-indanones with barbiturate-based olefins

Beilstein Journal of Organic Chemistry, 2022
Bifunctional thiourea-catalyzed asymmetric [3 + 2] annulation reactions of 2-isothiocyanato-1-indanones with barbiturate-based olefins have been developed to afford chiral dispiro[indene-pyrrolidine-pyrimidine]s.
Jiang-Song Zhai, Da-Ming Du
doaj   +1 more source

Cyclotrimerization Approach to Symmetric [9]Helical Indenofluorenes: Diverting Cyclization Pathways

Chemistry – A European Journal, Volume 29, Issue 58, October 18, 2023., 2023
Catalytic cyclotrimerization (Rh, Co, and Ni catalysts) of triyne 1 gives rise preferentially to [9]helical indenofluorene, whereas it thermal cyclization gives rise to polyaromatic hydrocarbon 3. The former reaction proceeds via classical alkyne cyclotrimerization, the latter via dehydro‐Diels–Alder reaction accompanied by unusual C−C cleavage.
Timothée Cadart, Tim Gläsel, Ivana Císařová, Róbert Gyepes, David Nečas, Marko Hapke, Martin Kotora   +6 more
wiley   +1 more source

Recent Advances in Multicomponent Electro‐Organic (Electrochemical) Synthesis of Heterocycles

Asian Journal of Organic Chemistry, Volume 12, Issue 8, August 2023., 2023
This review provides a summary of electrosynthesis methods that can be used as an alternative method for synthesis of complex organic molecules in pharmaceutical and biological applications. This method involves electro‐organic reactions occurring at room temperature and normal pressure through transferring electrons.
Sahar Imeni, Ata Makarem, Ramin Javahershenas   +2 more
wiley   +1 more source

Phytochemicals from Leucas zeylanica Targeting Main Protease of SARS-CoV-2: Chemical Profiles, Molecular Docking, and Molecular Dynamics Simulations

Biology, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a contemporary coronavirus, has impacted global economic activity and has a high transmission rate.
Mycal Dutta, Abu Montakim Tareq, Ahmed Rakib, Shafi Mahmud, Saad Ahmed Sami, Jewel Mallick, Mohammad Nazmul Islam, Mohuya Majumder, Md. Zia Uddin, Abdullah Alsubaie, Abdulraheem S. A. Almalki, Mayeen Uddin Khandaker, D.A. Bradley, Md. Sohel Rana, Talha Bin Emran   +14 more
doaj   +1 more source