Results 21 to 30 of about 1,947 (193)

Phytochemicals from Leucas zeylanica Targeting Main Protease of SARS-CoV-2: Chemical Profiles, Molecular Docking, and Molecular Dynamics Simulations

Biology, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a contemporary coronavirus, has impacted global economic activity and has a high transmission rate.
Mycal Dutta, Abu Montakim Tareq, Ahmed Rakib, Shafi Mahmud, Saad Ahmed Sami, Jewel Mallick, Mohammad Nazmul Islam, Mohuya Majumder, Md. Zia Uddin, Abdullah Alsubaie, Abdulraheem S. A. Almalki, Mayeen Uddin Khandaker, D.A. Bradley, Md. Sohel Rana, Talha Bin Emran   +14 more
doaj   +1 more source

Dispiro[fluorene-9,5′-[1,2,3,4]tetrathiane-6′,9′′-fluorene] [PDF]

Acta Crystallographica Section C Crystal Structure Communications, 2001
The tetrathiane ring of the title compound, C26H16S4, has a chair conformation and the molecule has approximate C2 symmetry. Each of the two fluorene ring systems is virtually planar, with the ring planes intersecting at an angle of 67.58 (5) degrees. This novel compound has been formed as a side product from the treatment of 9H-fluorene-9-thione with ...
Linden, Anthony, Gebert, Andreas, Heimgartner, Heinz   +2 more
openaire   +3 more sources

Crystal structure of ethyl 2′′,3-dioxo-7′,7a'-dihydro-1′H,3H,3′H-dispiro[benzo[b]thiophene-2,6′-pyrrolo[1,2-c]thiazole-5′,3′′-indoline]-7′-carboxylate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C23H20N2O4S2, the central pyrrolidine ring adopts an envelope conformation with the spiro C atom, shared with the benzothiophene ring system, as the flap.
M. P. Savithri, M. Suresh, R. Raghunathan, R. Raja, A. SubbiahPandi   +4 more
doaj   +1 more source

The Effect of Benzannulation on the Structures, Reactivity and Molecular Dynamics of Indenes, Pentalenes, Azulenes and Related Molecules

Molecules, 2022
The stabilising effect of benzannulation on isoindenes formed in the course of sigmatropic shifts of (C5H5)Fe(CO)2 or of organo-silyl groups, and on exocyclic allyl intermediates in the course of haptotropic shifts of organometallic fragments over ...
Michael J. McGlinchey
doaj   +1 more source

Structural and stereogenic properties of spiro- and ansa-substituted 1,3-propanedioxy derivatives of a spermine-bridged cyclotriphosphazene [PDF]

, 2006
Reaction of 1,3-propanediol with the achiral spermine-bridged cyclophosphazene 1 at various molar ratios in THF gives a number of spiro-and ansa-derivatives that exhibit different stereogenic properties, viz. racemic, meso or achiral forms. As expected,
Adem Kılıç, Alkubaisi, Allen, Beşli, Beşli, Beşli, Brandt, Coles, Coles, Contractor, David B. Davies, Davies, Dez, Fraser, Gönül Yenilmez Çiftçi, Kılıç, Labarre, Labarre, Otwinowski, Pirkle, Porwolik-Czomperlik, Rinaldi, Robert A. Shaw, Robert J. Eaton, Shaw, Sheldrick, Sheldrick, Simon J. Coles, Sullivan, Weissman   +29 more
core   +1 more source

Crystal structure of ethyl 5′′-fluoro-2′′,3-dioxo-6′,7′,8′,8a'-tetrahydro-2′H,3H,5′H-dispiro[benzo[b]thiophene-2,1′-indolizine-3′,3′′-indoline]-2′-carboxylate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C25H23FN2O4S, the fused piperidine ring of the octahydroindolizine ring system adopts a chair conformation and the five-membered ring has a twisted conformation on the N—C(spiro) bond.
R. Raja, J. Govindaraj, M. Suresh, R. Raghunathan, A. SubbiahPandi   +4 more
doaj   +1 more source

Electro‐Synthesis of Organic Compounds with Heterogeneous Catalysis

Advanced Science, Volume 10, Issue 1, January 4, 2023., 2023
In this review, the most recent advances in synthesizing value‐added chemicals by heterogeneous catalysis are summarized, and an overview of electrocatalytic oxidation and reduction processes as well as paired electrocatalysis is also provided. Abstract Electro‐organic synthesis has attracted a lot of attention in pharmaceutical science, medicinal ...
Tariq Ali, Haiyan Wang, Waseem Iqbal, Tariq Bashir, Rahim Shah, Yong Hu   +5 more
wiley   +1 more source

Crystal structure of ethyl 1′,1′′-dimethyl-2′′,3-dioxo-3H-dispiro[benzo[b]thiophene-2,3′-pyrrolidine-2′,3′′-indoline]-4′-carboxylate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C23H22N2O4S, the pyrrolidine ring has an envelope conformation with the spiro C atom, shared with the indoline ring system, as the flap. The mean planes of the benzothiophene and indoline ring systems are inclined to the mean plane
M. P. Savithri, M. Suresh, R. Raghunathan, R. Raja, A. SubbiahPandi   +4 more
doaj   +1 more source

An update on the synthesis and reactivity of spiro-fused β-lactams [PDF]

, 2018
Beta-Lactam ring-containing compounds play a pivotal role in drug design and synthetic chemistry. Spirocyclic beta-lactams, representing an important beta-lactam subclass, have recently attracted considerable interest with respect to new synthetic ...
D'hooghe, Matthias, Dao Thi, Hang
core   +1 more source

Copper‐Catalyzed Enantioselective Hydrosilylation of gem‐Difluorocyclopropenes Leading to a Stereochemical Study of the Silylated gem‐Difluorocyclopropanes

Chemistry – A European Journal, Volume 28, Issue 32, June 7, 2022., 2022
The copper‐catalyzed enantioselective hydrosilylation of gem‐difluorocyclopropenes providing the chiral gem‐difluorocyclopropanes is presented. The use of copper(I) chloride, chiral ligands including bidentate BINAPs and monodentate phosphoramidites, and silylborane Me2PhSi‐Bpin accompanying NaOtBu in methanol was appropriate for the enantioselective ...
Keisuke Sekine, Dai Akaishi, Kakeru Konagaya, Shigekazu Ito   +3 more
wiley   +1 more source