Results 11 to 20 of about 3,475,040 (327)
Determination of pKa values of fluphenazine analogs by reversed-phase high-performance liquid chromatography [PDF]
Acta Poloniae Pharmaceutica, 2023 Phenothiazine and its derivatives exhibit many properties. Hence they are the starting structures for many new potential drugs, biologically active compounds, dyes, etc.
Sobczak Agnieszka +3 more
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Favipiravir Determination in Pharmaceutical Formulation via HPLC Chromatographic Approach [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2023 Favipiravir is a broad-spectrum antiviral drug and it has increasing interest regarding its potential use in Covid-19 therapy. In the present work, a simple, fast, precise Reverse-Phase High-Performance Liquid Chromatography (RP-HPLC) technique was ...
Sabriye Aydinoglu, Metin Bozyel
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Frontiers in Bioscience-Landmark, 2022 Background: Diazinon is a widely used organophosphorus neurotoxic insecticide. It is a common environmental contaminant and a hazardous agri-waste. Its detection is critical to control entry into food systems and protect the environment. Methods: In this
Mai-Huong Thi Can +11 more
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IPC 2.0: prediction of isoelectric point and pKa dissociation constants
Nucleic Acids Res., 2021 The isoelectric point is the pH at which a particular molecule is electrically neutral due to the equilibrium of positive and negative charges. In proteins and peptides, this depends on the dissociation constant (pKa) of charged groups of seven amino ...
L. Kozlowski
semanticscholar +1 more source
Phosphorylated and Phosphomimicking Variants May Differ—A Case Study of 14-3-3 Protein
Frontiers in Chemistry, 2022 Protein phosphorylation is a critical mechanism that biology uses to govern cellular processes. To study the impact of phosphorylation on protein properties, a fully and specifically phosphorylated sample is required although not always achievable ...
Aneta Kozeleková +10 more
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Sensors, 2021 Several studies were devoted to the design of molecularly imprinted polymer (MIP)-based sensors for the detection of a given protein. Here, we bring elements that could contribute to the understanding of the interaction mechanism involved in the ...
Amal Tlili +7 more
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Molecules, 2022 The microscale thermophoresis (MST) technique was utilized to investigate lactoferrin–drug interaction with the iron chelator, deferiprone, using label-free system. MST depends on the intrinsic fluorescence of one interacting partner.
Mufarreh Asmari +7 more
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Asymptotic vibrational states of the H-3(+) molecular ion [PDF]
, 2005 Vibrational calculations for H-3(+) are performed using an accurate global ab initio potential energy surface. Fourteen bound states close to dissociation are found to have interesting long-range dynamics.
Munro, JJ, Ramanlal, J, Tennyson, J
core +1 more source
Hsp70 chaperones are non-equilibrium machines that achieve ultra-affinity by energy consumption
eLife, 2014 70-kDa Heat shock proteins are ATP-driven molecular chaperones that perform a myriad of essential cellular tasks. Although structural and biochemical studies have shed some light on their functional mechanism, the fundamental issue of the role of energy ...
Paolo De Los Rios, Alessandro Barducci
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Molecules, 2023 The interaction between SARS-CoV-2 spike RBD and ACE2 proteins is a crucial step for host cell infection by the virus. Without it, the entire virion entrance mechanism is compromised.
Jason Fauquet +4 more
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