Results 51 to 60 of about 1,185,001 (388)

Flow induced dissolution of femtoliter surface droplet arrays [PDF]

, 2018
The dissolution of liquid nanodroplets is a crucial step in many applied processes, such as separation and dispersion in food industry, crystal formation of pharmaceutical products, concentrating and analysis in medical diagnosis, and drug delivery in ...
Bao, Lei, Dyetta, Brendan, Lohseb, Detlef, Spandan, Vamsi, Verziccod, Roberto, Yang, Yantao, Zhang, Xuehua   +6 more
core   +3 more sources

Dissolution kinetics of South African coal fly ash and the development of a semi-empirical model to predict dissolution [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2015
Wet flue gas desulphurization (FGD) is a crucial technology which can be used to abate the emission of sulphur dioxide in coal power plants. The dissolution of coal fly ash in adipic acid is investigated by varying acid concentration (0.05-0.15M)
Koech Lawrence, Everson Ray, Neomagus Hein, Rutto Hilary   +3 more
doaj   +1 more source

Liquisolid Tablets Formulation of Atorvastatin Calcium Using Polyethylene Glycol 400 as Solvent and Some Carrier Materials

Indonesian Journal of Pharmacy, 2020
The dissolution of atorvastatin calcium need to be improved since included BCS Class II drugs with low solubility and high permeability, meaning that the dissolution affects the bioavailability of drugs.
Yulias Ninik Windriyati, Matsniyyatul Badriyah, Diar Arum Kusumaningtyas, Rian Lesta Riesmalia   +3 more
doaj   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Electrospun PLA Fibers Containing Metronidazole for Periodontal Disease

Drug Design, Development and Therapy, 2020
Mária Budai-Szűcs, 1 Attila Léber, 1 Lu Cui, 2, 3 Muriel Józó, 2, 3 Péter Vályi, 4 Katalin Burián, 5 Balázs Kirschweng, 2, 3 Erzsébet Csányi, 1 Béla Pukánszky 2, 3 ...
Budai-Szűcs M, Léber A, Cui L, Józó M, Vályi P, Burián K, Kirschweng B, Csányi E, Pukánszky B   +8 more
doaj  

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Hydrodynamics and mechanical stresses in pharmacopoeial and noncompendial dissolution testing [PDF]

Farmacja Polska, 2020
The first and an essential step of medication’s path inside the human body is a dissolution of an active pharmaceutical ingridient. A dissolution of oral dosage forms occurs as a result of physicochemical and mechanical stresses which are found in ...
Marcela Wiater, Dagmara Hoc, Jadwiga Paszkowska, Grzegorz Garbacz   +3 more
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Union dissolution and migration [PDF]

Demographic Research, 2016
Background: While there is a limited body of research regarding residential mobility and migration following union dissolution, there is a particular dearth of studies that go into detail about the factors that shape how union dissolution may result in long-distance migration.
Clara H. Mulder, Michael Thomas, Thomas J. Cooke   +2 more
openaire   +4 more sources

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source