Results 41 to 50 of about 2,373,415 (302)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Delighting Our Customers: Building Services Collaboratively with Learners at a Distance [PDF]

open access: yes, 2016
The Open University (OU) is the largest academic institution dedicated to distance learning in the United Kingdom, with over 173,000 students. Distance learning students can provide a unique perspective on the experience of the library.
Dick, Sam, Killick, Selena
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Group Leadership in Online Collaborative Learning [PDF]

open access: yes, 2005
The innovations in computer and communications technologies combined with on-going needs to deliver educational programs to students regardless of their physical locations, have lead to the innovation of distance education programs and technologies.
Kukulska-Hulme, Agnes
core  

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

The world of learning

open access: yesJournal of Open, Flexible and Distance Learning, 2012
Column about conferences events and new publications in distance learning.
Glenise Dreaver, Terry Hearn
doaj   +2 more sources

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Vertical Head Movements Influence Memory Performance for Words With Emotional Content

open access: yesFrontiers in Psychology, 2019
Numerous studies have found an association between valence and the vertical dimension of space (good-up, bad-down). This association has also been linked to sensorimotor experiences (e.g., body movements).
Laura K. Globig   +2 more
doaj   +1 more source

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