Results 51 to 60 of about 33,178 (299)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Neural observer-based path following control for underactuated unmanned surface vessels with input saturation and time-varying disturbance

International Journal of Advanced Robotic Systems, 2019
In this study, a new neural observer-based dynamic surface control scheme is proposed for the path following of underactuated unmanned surface vessels in the presence of input saturation and time-varying external disturbance.
Lei Wan, Jiangfeng Zeng, Yueming Li, Hongde Qin, Lei Zhang, Jian Wang   +5 more
doaj   +1 more source

Observer-Based Optimal Control of a Quadplane with Active Wind Disturbance and Actuator Fault Rejection

, 2023
Hybrid aircraft configurations with combined cruise and vertical flight capabilities are increasingly being considered for unmanned aircraft and urban air mobility missions. To ensure the safety and autonomy of such missions, control challenges including
Nadjim Horri (15913793), Mauro Innocente (15913850), Zaidan Zyadat (16918674), Thomas Statheros (15913787)   +3 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Similarities and differences between exosystem-model-based disturbance observer and model error compensator

SICE Journal of Control, Measurement, and System Integration
This paper clarifies the theoretical similarities and differences between the exosystem-model-based disturbance observer and the model error compensator. In 1972, Johnson proposed the exosystem-model-based disturbance observer.
Kana Shikada, Noboru Sebe
doaj   +1 more source

Disturbance Observer-Based Robust Model Predictive Control for a Voltage Sensorless Grid-Connected Inverter With an LCL Filter

IEEE Access, 2021
This paper proposes a disturbance observer-based robust model predictive control (MPC) for a voltage sensorless grid-connected inverter with an inductive-capacitive-inductive (LCL) filter.
Nguyen Ngoc Nam, Ngoc-Duc Nguyen, Changwoo Yoon, Young Il Lee   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Disturbance Observer-Based Robot End Constant Contact Force-Tracking Control

Complexity, 2019
A disturbance observer-based hybrid sliding mode impedance control method is proposed in this paper, which is able to achieve robot end constant contact force-tracking control without force/torque sensors.
Tie Zhang, Xiaohong Liang
doaj   +1 more source

Extending the TPTool MATLAB toolbox with LMI based observer and disturbance rejection design

Results in Control and Optimization, 2023
Present paper demonstrates the extensions of MATLAB TPtool toolbox. The toolbox does not include the LMI based observer and disturbance rejection design.
A. Wéber, M. Kuczmann
doaj   +1 more source