Results 71 to 80 of about 162,627 (299)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Backstepping Control with Disturbance Observer for Permanent Magnet Synchronous Motor

Journal of Control Science and Engineering, 2018
For the speed tracking control problem of Permanent Magnet Synchronous Motor (PMSM), a disturbance observer-based (DOB) backstepping speed tracking control method is presented in this paper.
Yong-Hong Lan, Lei-Zhou
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

WAMS-Based Online Disturbance Estimation in Interconnected Power Systems Using Disturbance Observer

Applied Sciences, 2019
In the event of a generator loss or disturbance, the power system frequency declines quickly and overall system stability is at risk. During these scenarios, under frequency load shedding is triggered to restore the power system frequency. The main stage
Hassan Haes Alhelou, Mohamad Esmail Hamedani Golshan, Takawira Cuthbert Njenda, Pierluigi Siano   +3 more
doaj   +1 more source

Control and measurement delay compensation in bilateral position control [PDF]

, 2011
The main aim of this study is the improvement of the previously presented disturbance observer based bilateral control approaches of the authors with a delay regulator and a model tracking control (MTC) that runs on the slave side.
Bogosyan, Seta, Gokasan, Metin, Gökaşan, Metin, Kuzu, Ahmet, Sabanovic, Asif, Şabanoviç, Asif   +5 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Adaptive finite-time fault-tolerant control scheme of UAV against combined faults

Scientific Reports
The control of unmanned aerial vehicles (UAVs) has been an active area of research over the past decade, particularly for operations in complex environments.
Xiangfeng Yan, Tao Li, Yuan Tian
doaj   +1 more source

Reciprocal Neural State–Disturbance Observer for Model-Free Trajectory Tracking of Robotic Manipulators

Mathematics
High-precision trajectory tracking of robotic manipulators is fundamentally challenged by strong nonlinear dynamics, unmodeled uncertainties, and external disturbances.
Binluan Wang, Yuchen Peng, Hongzhe Jin, Jie Zhao   +3 more
doaj   +1 more source