Results 71 to 80 of about 260,568 (212)
Muscle lactate dehydrogenase (LDH-A) catalyzes the reduction of pyruvate to lactate, the end product of anaerobic glycolysis. LDH-A is overexpressed in many cancers prior to and even when tumors receive adequate oxygen, and lactate has multiple cellular ...
Lisa Landino, Lydia Boike, Taylor Lain
doaj +1 more source
Characterising the expression and interactions of the Endoplasmic Reticulum Oxidoreductase Erol β [PDF]
Proteins destined for the secretory pathway and endoplasmic reticulum (ER) resident proteins are targeted to the ER through an N-terminal signal sequence. Proteins then follow a post-translational maturation process to fold into functional proteins.
Gunasekara, Sanjika Dias
core
Thiol-Disulfide Balance in Fibromyalgia: A Case-Control Study
Aim. We aimed to examine the thiol-disulfide (SS) balance, a recognized marker of oxidative stress, in fibromyalgia syndrome (FMS). Methods. The study comprised 98 female participants (61 newly diagnosed patients and 37 patients under treatment) with ...
Esra Sahingoz Bakirci +7 more
doaj +1 more source
Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Peptide Ligands and Drugs
Multicyclic peptides with stable 3D structures are a kind of novel and promising peptide formats for drug design and discovery as they have the potential to combine the best characteristics of small molecules and proteins.
Hongtan Liu (12244451) +10 more
core +1 more source
Lactate Dehydrogenase-B Oxidation and Inhibition by Singlet Oxygen and Hypochlorous Acid
Alterations in cellular energy metabolism are a hallmark of cancer and lactate dehydrogenase (LDH) enzymes are overexpressed in many cancers regardless of sufficient oxygen and functional mitochondria. Further, L-lactate plays signaling roles in multiple
Lisa M. Landino, Emily E. Lessard
doaj +1 more source
A series of novel ferrocenyl- and aryl-phosphonofluorodithioic salts, adducts, and esters has been prepared. The reaction of 2,4-diferrocenyl-1,3,2,4-diathiadiphosphetane 2,4-disulfide {[FcP(μ-S)S]2, FcLR} with dry KF or tetrabutylammonium fluoride (TBAF)
Junyi Du +12 more
core +1 more source
Scorpion venom contains various bioactive peptides, many of which exhibit insecticidal activity. The majority of these peptides have a cystine-stabilized α-helix/β-sheet (CSαβ) motif. In addition to these peptides, scorpion venom also contains those with
Masahiro Miyashita +4 more
doaj +1 more source
Occupational exposure to carbon-disulfide [PDF]
"The recommended standard is given limiting employee exposure to less than 3 milligrams per cubic meter of air (1ppm) as a time weighted average concentration for up to a 10 hour work shift in a 40 hour workweek or less than 30 milligrams per cubic meter
core +1 more source
The role of thiol-disulfide homeostasis in gouty arthropathy
Objective: Gout, the most common form of crystal-induced arthritis, is characterized by the accumulation of monosodium urate crystals within the joints.
Sevinç Can Sandıkçı +4 more
doaj +1 more source
Synthesis of a resin monomer-soluble polyrotaxane crosslinker containing cleavable end groups
A resin monomer-soluble polyrotaxane (PRX) crosslinker with cleavable end groups was synthesized to develop degradable photosetting composite resins. The PRX containing 50 α-cyclodextrins (α-CDs) with disulfide end groups was initially modified with n ...
Ji-Hun Seo +3 more
doaj +1 more source

