Results 91 to 100 of about 52,814 (284)

Synthetic Biology and Metabolic Engineering of Microalgae for Sustainable Lipid and Terpenoid Production: An Updated Perspective

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Microalgae are increasingly recognised as powerful platforms for the sustainable production of lipids and terpenoids, with expanding applications in the food, fuel and biomanufacturing industries. In this updated review, we consolidate and critically assess the most recent advances in synthetic biology and metabolic engineering of key ...
Ty Shitanaka   +6 more
wiley   +1 more source

Bioactive Compounds From Torbangun [Plectranthus Amboinicus (Lour.) Spreng] Chloroform Fraction Induce Apoptosis in Breast Cancer (Mcf-7 Cells) in Vitro [PDF]

open access: yes, 2017
Torbangun (Plectranthus amboinicus (Lour.) Spreng) is a medicinal plant that has been traditionally used in tropical countries to cure various illnesses.
Andarwulan, N. (Nuri)   +3 more
core  

Functional Characterization and Evolution of the Isotuberculosinol Operon in Mycobacterium Tuberculosis and Related Mycobacteria [PDF]

open access: yes, 2012
Terpenoid metabolites are important to the cellular function, structural integrity, and pathogenesis of the human-specific pathogen Mycobacterium tuberculosis (Mtb).
Davenport, Emily   +4 more
core   +4 more sources

Heterologous Production of Forskolin in Tobacco (Nicotiana tabacum) via Glandular Trichome Specific Engineering and Metabolic Flux Redirection

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Plants are promising bioreactor for the sustainable and scalable production of high‐value natural bioactive compounds, because they can synthesise phytochemicals from CO2, light, water and minerals through their innate photosynthetic carbon assimilation machinery.
Xuan Sun   +8 more
wiley   +1 more source

Levels of cafestol, kahweol, and related diterpenoids in wild species of the coffee plant coffea [PDF]

open access: yes, 1997
Specific fatty acids and sterols in food composites from seven countries were analyzed. In the 1960s, groups of 8 to 49 men from 16 cohorts, ages 40–59 years and living in the United States, Finland, the Netherlands, Italy, Greece, the former Yugoslavia,
Bovenkamp, P. van de   +5 more
core   +3 more sources

Mass Spectrometry Imaging Combined With Single‐Cell Transcriptional Profiling Reveals the Multidimensional Spatial Distributions and Biosynthetic Pathways of Medicinal Components in Andrographis paniculata

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT The synthesis and accumulation of active ingredients in medicinal plants are distributed in specific organs, tissues, and cell types, which are important for the exploitation of medicinal plants. However, the fine distribution of active ingredients is difficult to know. Here, the system of mass spectrometry imaging (MSI) integrated with single‐
HaiSheng Zeng   +14 more
wiley   +1 more source

Efficacy of Diterpene Polyalthic Acid Combined with Amphotericin B against Leishmania amazonensis In Vitro

open access: yesPharmaceuticals
Background/Objectives: Leishmaniasis, a neglected disease caused by Leishmania spp. including L. amazonensis, urgently requires new treatments. Polyalthic acid (PA), a natural diterpene from Copaifera spp., has previously demonstrated significant ...
Ana Carolina Bolela Bovo Candido   +7 more
doaj   +1 more source

Pushing the limits of concertedness. A waltz of wandering carbocations. [PDF]

open access: yes, 2019
Among the array of complex terpene-forming carbocation cyclization/rearrangement reactions, the so-called "triple shift" reactions are among the most unexpected.
Castiñeira Reis, Marta   +3 more
core  

Towards elucidating carnosic acid biosynthesis in Lamiaceae: Functional characterization of the three first steps of the pathway in Salvia fruticosa and Rosmarinus officinalis [PDF]

open access: yes, 2015
Carnosic acid (CA) is a phenolic diterpene with anti-tumour, anti-diabetic, antibacterial and neuroprotective properties that is produced by a number of species from several genera of the Lamiaceae family, including Salvia fruticosa (Cretan sage) and ...
Božić, Dragana   +17 more
core   +5 more sources

When Metabolomics Meets Quantitative Genetics: An Integrative Strategy to Elucidate Plant Resistance Mechanisms

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Gene pyramiding in crop varieties offers a promising strategy to achieve sustainable production and reduce reliance on pesticides. However, stacking resistance genes without understanding their biological functions may result in transient protection.
Romane Lapous   +6 more
wiley   +1 more source

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