Results 131 to 140 of about 15,361 (230)

Notch signaling during human T cell development [PDF]

, 2012
Notch signaling is critical during multiple stages of T cell development in both mouse and human. Evidence has emerged in recent years that this pathway might regulate T-lineage differentiation differently between both species.
A Galy, A Krueger, A Sambandam, A Wilson, A Wolfer, AC Jaleco, AI Garbe, AP Weng, B Blom, B Reizis, B Vandekerckhove, BN Weber, C Benne, CC Tydell, CN Ting, D Hockemeyer, D Hockemeyer, E Robey, EM Six, ES David-Fung, F Klein, F Radtke, F Radtke, F Timmermans, F Weerkamp, F Weerkamp, G Awong, H Hirata, H Neves, H Wang, HT Petrie, HY Kueh, I Hoebeke, I Maillard, I Maillard, I Walle Van de, I Walle Van de, J Buer, J Gotter, J Plum, J Shi, JS Yuan, K Heinzel, K Hozumi, K Li, K Maki, K Tanigaki, L Li, M Ciofani, M Ciofani, M Ciofani, M Garcia-Peydro, M Ghisi, M Magri, M Smedt De, M Smedt De, M Smedt De, M Smedt De, MA Yui, MD Green, ML Joachims, N Lefort, P Beatus, P Doerfler, P Li, QL Hao, QL Hao, R Haddad, RN Motte-Mohs La, S Coppernolle Van, S Doulatov, S Gonzalez-Garcia, S Suliman, S Verbeek, SK Durum, SK Ye, SM Lehar, SY Lee, T Hosoya, T Ikawa, T Ikawa, T Kreslavsky, T Kreslavsky, T Palomero, T Taghon, T Taghon, T Taghon, T Taghon, T Taghon, T Taghon, TB Feyerabend, TM Schmitt, TN Taghon, W Dontje, WA Dik, Y Wu, YR Carrasco, Z Galic   +97 more
core   +2 more sources

Astrocytic DLL4-NOTCH1 signaling pathway promotes neuroinflammation via the IL-6-STAT3 axis

Journal of Neuroinflammation
Under neuroinflammatory conditions, astrocytes acquire a reactive phenotype that drives acute inflammatory injury as well as chronic neurodegeneration.
Pierre Mora, Margaux Laisné, Célia Bourguignon, Paul Rouault, Béatrice Jaspard-Vinassa, Marlène Maître, Alain-Pierre Gadeau, Marie-Ange Renault, Sam Horng, Thierry Couffinhal, Candice Chapouly   +10 more
doaj   +1 more source

DLL4-targeted CAR-T therapy sensitizes neoadjuvant chemotherapy via eliminating cancer stem cells and reshaping immune microenvironment in HER2+ breast cancer

Journal for ImmunoTherapy of Cancer
Background Neoadjuvant therapy with trastuzumab, pertuzumab and paclitaxel (THP) has significantly improved the prognosis of patients with human epidermal growth factor receptor 2 (HER2)+ breast cancer (BC).
Tianxing Zhou, Yongjie Xie, Yanfang Yang, Ziyun Liu, Jingrui Yan   +4 more
doaj   +1 more source

VEGFR3 and Notch signaling in angiogenesis [PDF]

, 2014
Blood and lymphatic vessels form extensive networks throughout the body, which function in order to deliver oxygen and nutrients to the tissues, to remove extravasated fluid and to absorb dietary lipids.
Zarkada, Georgia
core  

DLL4 Gene [PDF]

, 2020
openaire   +1 more source

Cis-activation in the Notch signaling pathway [PDF]

, 2019
The Notch signaling pathway consists of transmembrane ligands and receptors that can interact both within the same cell (cis) and across cell boundaries (trans). Previous work has shown that cis-interactions act to inhibit productive signaling.
Elowitz, Michael B., Nandagopal, Nagarajan, Santat, Leah A.   +2 more
core   +1 more source

DLL4 wt Allele [PDF]

, 2020
openaire   +1 more source

Delta-like 4 (DLL4) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Correlation between serum level of Delta Like Ligand 4 and different types of Diabetic Retinopathy and Maculopathy in Egyptian patients

Journal of the Egyptian Ophthalmological Society
Objectives Delta-like ligand-4 (DLL4) is responsible for normal physiological and pathological retinal vasculature. In this study, we aim to compare DDL4 serum levels in both healthy and diabetic patients.
Mohamed A.R. Rady, Hany ElMekawey, Marwa ElSharkawy, Shaymaa H. Salah   +3 more
doaj   +1 more source

Delta-like 4 (DLL4) [PDF]

Science-Business eXchange, 2012
openaire   +1 more source