Results 111 to 120 of about 202,224 (260)

Beyond anaerobic respiration—new physiological roles for DmsABC and other S-/N-oxide reductases in Escherichia coli

Journal of Bacteriology
Sulfoxide reductases in pathogenic bacteria have recently received increasing attention for their association with virulence and survival within the host.
Qifeng Zhong, Marufa Nasreen, Ruizhe Yang, Michel Struwe, Bostjan Kobe, Ulrike Kappler   +5 more
doaj   +1 more source

Redox status of patients before cardiac surgery

Redox Report, 2018
Objectives: Redox regulation plays a crucial role in balancing the cardiovascular system. In this prospective study we aimed to identify currently unknown correlations valuable to cardiovascular research and patient management.
Anna Katharina Schuh, Babak Sheybani, Esther Jortzik, Bernd Niemann, Jochen Wilhelm, Andreas Boening, Katja Becker   +6 more
doaj   +1 more source

DMSO reductase fromRhodobacter capsulatus [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 1996
A. S. McAlpine, S. Bailey
openaire   +1 more source

CAFs‐mediated histone lactylation reprograms cholesterol metabolism in colorectal cancer to drive CD8+ T cell immunosuppression

The Journal of Pathology, EarlyView.
Abstract The progression of colorectal cancer (CRC) is critically regulated by cancer‐associated fibroblasts (CAFs) within the tumor microenvironment (TME), yet the specific molecular mechanisms by which CAFs influence CRC remain unclear. This study reveals the mechanism by which CAFs promote CRC malignant progression and immune suppression through ...
Huachi Li, Jun Hu, Lei Huang, Zihao Wang, Haoran Tao, Feng Cao, Min Xie   +6 more
wiley   +1 more source

Dihydroartemisinin Engages NQO1 and Promotes Ferroptosis‐Related Oxidative Stress in Non‐Small Cell Lung Cancer

Phytotherapy Research, EarlyView.
Dihydroartemisinin Engages NQO1 and Promotes Ferroptosis‐Related Oxidative Stress in Non‐Small Cell Lung Cancer. ABSTRACT Dihydroartemisinin (DHA), a bioactive derivative of Artemisia annua L. (AAL), has shown antitumor activity in several malignancies, including non‐small cell lung cancer (NSCLC).
Xiuli Guo, Gan Tao, Mini Zhang, Linzhi Han, Sisi Yan, Chunsheng Wang, Jianguo Zhang, Xiaowan Guo, Kehua Hu, Yan Gong, Qiuji Wu, Conghua Xie   +11 more
wiley   +1 more source

Individual capacity for DNA repair and maintenance of genomic integrity: a fertile ground for studies in the field of assisted reproduction

Biotechnology & Biotechnological Equipment, 2016
Many factors may affect the chances for successful pregnancy, especially at a later age. Fertility evaluations including genetic analysis are recommended to couples that have not achieved pregnancy within 6–12 months of unprotected intercourse.
Radoslava Vazharova, Ivo Kremensky
doaj   +1 more source

Site-directed mutagenesis of dimethylsulfoxide reductase from Rhodobacter capsulatus: The critical roles of tyrosine-114 and tryptophan-116

, 2003
The crystal structure of six functionally-distinct enzymes of the DMSO reductase family of molybdenum enzymes has revealed that the tertiary structure of the polypeptide that binds the bis(MGD)Mo cofactor is highly conserved. Differences in the catalytic
Ridge, Justin P., Aguey-Zinsou, Kondo-Francois, McEwan, Alastair G., Bernhardt, Paul V., Hanson, Graeme R.   +4 more
core   +1 more source

Dioscin Promotes Ferroptosis in Cervical Cancer Cells via the TIGAR‐ROS Axis

Cancer Science, EarlyView.
Dioscin suppresses cervical cancer progression by promoting ferroptosis. Mechanistically, Dioscin binds to TIGAR and inhibits TIGAR function, elevating ROS levels and inducing ferroptosis. ABSTRACT Cervical cancer seriously threatens women's life and health, highlighting the urgent need for targeted therapies.
Yameng Liu, Hongli Xi, Shaoju Min, Hanlin Yang, Li Hou, Hailong Zhang, Yujie Tan   +6 more
wiley   +1 more source

Isolation of transposon Tn 5 insertion mutants of Rhodobacter capsulatus unable to reduce trimethylamine-N-oxide and dimethylsulphoxide

, 1988
1) Rhodobacter capsulatus (formerly Rhodopseudomonas capsulata) strain 37b4 was subjected to transposon Tn 5 mutagenesis. 2) Kanamycin-resistant transconjugants were screened for their inability to reduce trimethylamine-N-oxide (TMAO) as judged by the ...
Ferguson, S. J., Kelly, D. J., Jackson, J. B., Richardson, D. J.   +3 more
core   +1 more source

Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells

The FEBS Journal, EarlyView.
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe, Ricardo Alva, Fereshteh Moradi, Sarah Alderman, Ping Liang, Jeffrey A. Stuart   +5 more
wiley   +1 more source