Results 121 to 130 of about 35,348 (219)

Novel Thiazolylimidazole Hybrids as Promising Antileishmanial Agents: Rational Design and Biological Evaluation. [PDF]

Pathogens
Ramírez-Sandoval C, Campos-Aldrete ME, Meléndez-Camargo ME.   +2 more
europepmc   +1 more source

Impacts of N‐glycanase1 (NGLY1) Down Regulation on the Function of Mitochondria

Journal of Cellular Biochemistry, Volume 127, Issue 8, August 2026.
ABSTRACT N‐glycanase 1 (NGLY1) is involved in intracellular misfolded protein degradation, releasing a de‐N‐glycosylated protein and a complete N‐oligosaccharide. Enzymatic defects in NGLY1 may cause NGLY1‐related congenital disorder of deglycosylation (NGLY1‐CDDG). NGLY1 patients exhibit cognition and coordination defects, and the regulatory impact of
Yanwen Chen, Ruijie Liu, Shaoxing Zhang, Yuxin Zhang, Qiange Lin, Yilin Ye, Shuying Yuan, Xinrong Lu, Linfei Wang, Li Chen, Guiqin Sun   +10 more
wiley   +1 more source

5α-Reductase underscores the development of pectoral fin breeding tubercles in zebrafish. [PDF]

Commun Biol
Xu Z, Zeng X, Zhang C, Tong B, Dong Z, Wang C, Liu S, He L, Li G, Qu Q.   +9 more
europepmc   +1 more source

Monitoring the Effect of Tributyltin Salicylate and Propionate, Retinoid X Receptor Ligands, on Heat Shock Protein Expression in MDA‐MB‐231 Cells by MALDI MS/MS

Journal of Mass Spectrometry, Volume 61, Issue 8, August 2026.
ABSTRACT Organotin (IV) compounds are known to induce apoptosis via the intrinsic mitochondrial pathway, which is a key mechanism of effective anticancer therapy. Their ability to selectively promote apoptotic cell death highlights their potential as chemotherapeutic agents. In this study, the in vitro effects of two triorganotin compounds, tributyltin
Dana Strouhalova, Dana Macejova, Julius Brtko, Janette Bobalova   +3 more
wiley   +1 more source

The Human Gut Microbiome Metabolizes Diverse Bioactive Coumarins via α,β-Unsaturated Lactone Reduction. [PDF]

J Nat Prod
Mingolelli G, Bashatwah RM, Jurek MJ, Chauvin IM, Orjala J, Riley AP, Burdette JE, Henke MT.   +7 more
europepmc   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Elevated Expression of Selenoprotein Synthesis Enzyme SEPHS2 Driven by ATF4 Promotes the Resistance to Ferroptosis in Prostate Cancer

MedComm, Volume 7, Issue 8, August 2026.
Under the treatment of ferroptosis inducers, the expression of SEPHS2 is upregulated, driven by ATF4, to increase the biosynthesis of selenoproteins (e.g., GPX4) to promote resistance to ferroptosis. ABSTRACT While it has been reported that antioxidant selenoproteins are crucial for anti‐ferroptosis in tumors, it remains unclear whether and how ...
Shijia Bao, Xinxing Du, Zhenkeke Tao, Huixiang Xiao, Jia Zhang, Zhenzhen Wen, Wei‐Qiang Gao, Baijun Dong, Yu‐Xiang Fang, Jianjun Sha   +9 more
wiley   +1 more source

Elucidating the physiological significance of iodate reduction in Shewanella species

mLife, Volume 5, Issue 4, Page 507-519, August 2026.
Abstract The reduction of iodate by Shewanella species plays a crucial role in iodine biogeochemical cycling. However, the physiological significance of this reduction process remains poorly understood, because Shewanella species are capable of reducing only low concentrations of iodate.
Ziyi Wang, Lingyu Hou, Yidan Hu, Zhou Jiang, Yiran Dong, Liang Shi, Yongguang Jiang   +6 more
wiley   +1 more source

Radiobiology studies of gold nanoparticle‐enhanced radiosensitization in proton therapy

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Approximately 50%$\%$ of newly diagnosed cancer patients worldwide receive radiotherapy, most commonly with X‐rays. Proton therapy has emerged as a promising alternative, offering complementary advantages over conventional X‐rays due to its highly localized energy deposition at the Bragg peak, thereby reducing radiation exposure to ...
N. Fuster‐Martínez, D. H. Saucedo‐Cuberes, M. C. Jiménez‐Ramos, D. Esperante, J. M. Espino, J. Fuster, J. F. Belén‐Aguilar, L. González‐López, P. Huertas, S. Jimeno, I. Mingarro, D. Pascual, D. Suárez‐García, M. J. García‐Murria   +13 more
wiley   +1 more source

Curcumin Attenuates Aroclor 1254-Induced Oxidative, Genotoxic, and Apoptotic Alterations in HepG2 Cells. [PDF]

J Biochem Mol Toxicol
Erkekoğlu P, Erdemli Köse SB, Tezel Yalçın H, Çakır DA.   +3 more
europepmc   +1 more source