Results 131 to 140 of about 35,348 (219)

Targeting fibrosis in the treatment of lower urinary tract dysfunction

The Journal of Pathology, Volume 269, Issue 4-5, Page 493-503, August 2026.
Abstract Benign prostatic hyperplasia (BPH) is a widely prevalent age‐associated disease that is the main contributor to lower urinary tract dysfunction (LUTD) in aging men. Although prostate fibrosis has been recognized as a contributor to BPH pathophysiology, there are not any clinically available therapeutics that target this aspect of disease ...
Ajinkya R Limkar, Sophia M Vrba, Emily A Ricke, Zsuzsanna Fabry, Matthew S Lee, Kevin T McVary, William A Ricke   +6 more
wiley   +1 more source

Multigram-Scale Asymmetric Alkene Reduction Catalyzed by a Thermostable Flavin Ene-Reductase. [PDF]

Org Process Res Dev
Wolder AE, Höfler GT, Mayol O, Opperman DJ, Hollmann F, Paul CE.   +5 more
europepmc   +1 more source

Preclinical Evaluation of Berry Extracts as a Nutritional Intervention to Alleviate Myocardial Ischemia–Reperfusion Injury and Atherosclerosis Development

Phytotherapy Research, Volume 40, Issue 8, Page 5299-5315, August 2026.
Schematic representation of the experimental design and the proposed mechanisms underlying the cardioprotective and anti‐atherosclerotic effects of Greek‐derived berry extracts. C57BL/6 mice with WD–induced MS and ApoE−/− mice with atherosclerosis received chronic supplementation with WMex or BBex.
Lydia Symeonidi, Panagiota‐Efstathia Nikolaou, Panagiotis Stathopoulos, Andriana Christodoulou, Alexandra Svouraki, Panagiotis Efentakis, Christina Chania, Angeliki Choustoulaki, Maria Xenaki, Anna Agapaki, Maria Tsoumani, Nikolaos Kostomitsopoulos, Ioulia Tseti, Gemma Vilahur, Alexios‐Leandros Skaltsounis, Ioanna Andreadou   +15 more
wiley   +1 more source

Characterization of the Orphan Cytochrome P450 CYP107J1 From Bacillus subtilis Through Peroxygenase Activity Engineering. [PDF]

Microb Biotechnol
Kato H, Hashimoto T, Das T, Doherty DZ, Bell SG, Furuya T.   +5 more
europepmc   +1 more source

Porous Organic Polymers: From Molecular Design to Scalable Technologies

Small, Volume 22, Issue 46, 18 August 2026.
This review introduces porous organic polymers (POPs) for a wide range of applications, including energy storage, gas adsorption, catalysts, adsorbents, biomedical applications, sensors, and other exciting fields, and critically analyzes the synthesis and modification, and how structural topology influences the composites' architecture of POPs, along ...
Hossein Mashhadimoslem, Hadi Shayesteh, Simindokht Zarei‐Shokat, Rokhsareh Bakhtiari, Sheyda Abedi‐Banaei, Zahra Sheikhlouiharzand, Parnia Mohebimanesh, Seyed Mohammad Amin Ojagh, Bahareh Bakhtiari, Ali Maleki, Theo G. M. van de Ven, Sohrab Zendehboudi, Ali Elkamel   +12 more
wiley   +1 more source

A Multi-Target Phytotherapeutic Approach to Benign Prostatic Hyperplasia: Preclinical Characterization of a PhytoBPH-Mix. [PDF]

Nutrients
Amante C, De Soricellis C, Sellitto MR, Falcone G, Luccheo L, Luccheo G, Gaudio PD.   +6 more
europepmc   +1 more source

Denitrification Modularity and Its Environmental Controls in Transiently Versus Permanently Anoxic Marine Systems

Environmental Microbiology, Volume 28, Issue 8, August 2026.
Denitrification modularity is controlled by several environmental factors, especially concentrations of carbon and nitrogen substrates. In permanently anoxic environments, longer pathways are favored by high carbon/nitrate ratio, consistent with thermodynamic expectations and ecological models. In seasonal and transient anoxia, environmental complexity
J. Catherine Hexter, Weiyi Tang, Samantha G. Fortin, Amal Jayakumar, Bess B. Ward   +4 more
wiley   +1 more source

Advancing the Resolution of the Sulfur Compound Disproportionation Puzzle in Dissulfuribacter Thermophilus S69ᵀ Through Quantitative Label‐Free Comparative Proteomics

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
To date, only three microorganisms have been functionally characterised for sulfur disproportionation. Our work identifies a fourth example and provides novel proteomic insights into its underlying pathways. These findings advance our understanding of microbial sulfur catabolism and highlight the ecological role of D.
Marilina Fernandez, Barbara Schoepp‐Cothenet, Marie Hemon, Carine Rodrigues‐Machado, Lukas V. F. Novák, Xavier Philippon, Sébastien Laurent, Céline Henry, Karine Alain   +8 more
wiley   +1 more source

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

British Journal of Pharmacology, Volume 183, Issue 15, Page 4399-4415, August 2026.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci, Troels Kjær Rosenbæk, Samuel J. Windross, Ulrik B. Keiding, Estéfano Pinilla, Katrine P. Stuckert, Jakob Hansen, Camilla B. Nielsen, Jemila Peter Gomes, Lucy R. Davies, Johan Palmfeldt, Volker Loeschcke, Charlotte U. Andersen, Ulf Simonsen, Thomas B. Poulsen, Mogens Johannsen   +15 more
wiley   +1 more source

Design, synthesis, and antibacterial activity study of pyrroloquinazoline diamine derivatives. [PDF]

J Enzyme Inhib Med Chem
Cheng M, Tian Y, Shang J, He W, Zheng Y, Yan C, Chen X, Li J, Jiang Y, Fu Q, Deng X, Xiao X, Song M.   +12 more
europepmc   +1 more source