Results 51 to 60 of about 72,448 (283)

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

Access to and use of clinical services and disease-modifying therapies by people with progressive multiple sclerosis in the United Kingdom [PDF]

, 2017
Background: According to current UK guidelines everyone with progressive MS should have access to an MS Specialist but levels of access and use of clinical services is unknown.
Campbell, Campbell, Department for Communities and Local Govenment, Devlin, Edmonds, EuroQol Group, Ford, Fox, Healthcare Improvement Scotland, Hobart, Holland, Jones, Kersten, Levesque, Lonergan, Mackenzie, MacLurg, Markwick, Miller, Montalban, MS Society, Mynors, National Institute for Health and Care Excellence, Office for National Statistics, Scolding, Scottish Office for National Statistics, The World Bank   +26 more
core   +2 more sources

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Optimal Cooperative MAC Protocol with Efficient Selection of Relay Terminals [PDF]

, 2010
A new cooperative protocol is proposed in the context of wireless mesh networks. The protocol implements ondemand cooperation, i.e. cooperation between a source terminal and a destination terminal is activated only when needed.
Escrig, Benoît
core   +2 more sources

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Higher order forward spin polarizability [PDF]

, 2010
As a guideline for future experiments to extract the four (leading) spin polarizabilities of the nucleon, we have constructed the forward amplitude for polarized Compton scattering by dispersion integrals.
Ahrens, Ahrens, Ahrens, Ahrens, Ahrens, Alexandru, Amsler, Arndt, B. Pasquini, Babusci, Bernard, Christensen, D. Drechsel, Detmold, Detmold, Drechsel, Drechsel, Drechsel, Drechsel, Dutz, Dutz, Engelhardt, Fearing, Guerrero, Hanstein, Hemmert, Hildebrandt, Hildebrandt, Holstein, Kamalov, Korkmaz, Lee, Lensky, Olmos de Leon, P. Pedroni, Pascalutsa, Pasquini, Salomon, Schumacher, Shintani, Vijaya Kumar   +40 more
core   +2 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

On the DMT of TDD-SIMO Systems with Channel-Dependent Reverse Channel Training

, 2012
This paper investigates the Diversity-Multiplexing gain Trade-off (DMT) of a training based reciprocal Single Input Multiple Output (SIMO) system, with (i) perfect Channel State Information (CSI) at the Receiver (CSIR) and noisy CSI at the Transmitter ...
Bharath, B. N., Murthy, Chandra R.
core   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Indolethylamine-N-methyltransferase Polymorphisms: Genetic and Biochemical Approaches for Study of Endogenous N,N,-dimethyltryptamine

Frontiers in Neuroscience, 2018
N,N-dimethyltryptamine (DMT) is a powerful serotonergic psychedelic whose exogenous administration elicits striking psychedelic effects in humans. Studies have identified DMT and analogous compounds (e.g., 5-hydroxy-DMT, 5-methoxy-DMT) alongside of an ...
Jon G. Dean
doaj   +1 more source