Results 71 to 80 of about 29,043 (297)

A Single Dose of 5-MeO-DMT Stimulates Cell Proliferation, Neuronal Survivability, Morphological and Functional Changes in Adult Mice Ventral Dentate Gyrus

open access: yesFrontiers in Molecular Neuroscience, 2018
The subgranular zone (SGZ) of dentate gyrus (DG) is one of the few regions in which neurogenesis is maintained throughout adulthood. It is believed that newborn neurons in this region encode temporal information about partially overlapping contextual ...
Rafael Vitor Lima da Cruz   +4 more
doaj   +1 more source

Indolethylamine N-methyltransferase (INMT) is not essential for endogenous tryptamine-dependent methylation activity in rats

open access: yesScientific Reports, 2023
Indolethylamine N-methyltransferase (INMT) is a transmethylation enzyme that utilizes the methyl donor S-adenosyl-L-methionine to transfer methyl groups to amino groups of small molecule acceptor compounds.
Nicolas G. Glynos   +7 more
doaj   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno   +19 more
wiley   +1 more source

Psychological and physiological effects of extended DMT. [PDF]

open access: yes
N,N-Dimethyltryptamine (DMT) is a serotonergic psychedelic that induces a rapid and transient altered state of consciousness when inhaled or injected via bolus administration.
Uthaug, Malin V.   +20 more
core   +1 more source

Clinical characteristics and concordance of anti‐MDA5 autoantibodies: A multicentre Australian study

open access: yesArthritis Care &Research, Accepted Article.
Objectives In Australia, anti‐MDA5 antibodies are exclusively tested by line immunoblot assay (LIA). The clinical concordance of a LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies.
Syed B Ali   +11 more
wiley   +1 more source

Personalized Network‐Guided Neuromodulation Enhances Human Working Memory

open access: yesAdvanced Science, EarlyView.
A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan   +13 more
wiley   +1 more source

Rate-adaptive DFT-spread DMT and CDMA-DMT for 1-mm SI-POF short-range links [PDF]

open access: yes, 2013
In this letter, rate-adaptive bit-loading techniques are explored for maximizing the transmission rate of spreading multicarrier modulation schemes over step index plastic optical fiber (SI-POF) short range transmission links.
Syvridis, D.   +3 more
core  

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

open access: yesAdvanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes   +15 more
wiley   +1 more source

Rational Molecular Design to Improve Digital Polymer Readout in Aerolysin‐Based Nanopore Sequencing

open access: yesAngewandte Chemie, EarlyView.
Nanopore sensing holds significant yet underexplored potential for decoding synthetic digital polymers. In this study, we synthesized an extensive library of sequence‐defined poly(phosphodiester)s and evaluated their performance in aerolysin‐based sequencing. By systematically optimizing molecular parameters, we identified an ideal combination of coded
Zhaozheng Yang   +9 more
wiley   +2 more sources

Comparison of Geometrically Shaped and Probabilistically Shaped Bit-Loading DMT for Optical Interconnect System

open access: yesIEEE Photonics Journal, 2020
We experimentally demonstrate the transmission performance of the bit-loading discrete multi-tone (DMT) signal in intensity modulation and direct detection (IM-DD) system with a transmission distance of 2km and a net data rate of 108-Gb/s by two ...
Junjie Ding, Jiao Zhang, Jianjun Yu
doaj   +1 more source

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