Results 81 to 90 of about 72,448 (283)

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

Advanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu, Weize Xu, Da Lin, Leqiang Sun, Jinxia Dai, Gang Cao   +5 more
wiley   +1 more source

Disparities in patient share and characteristics between disease-modifying therapy-treated and -untreated people with multiple sclerosis in Germany: a claims data analysis from 2017 to 2022

Frontiers in Neurology
IntroductionDespite significant advances in multiple sclerosis (MS) treatment, a substantial proportion of people with MS (pwMS) remains untreated with disease-modifying therapies (DMTs).
Ann-Sophie Stratil, Steffeni Papukchieva, Nils-Henning Neß, Inge Wolf, Antonios Bayas, Peter Flachenecker, Benjamin Friedrich   +6 more
doaj   +1 more source

Comparison of Geometrically Shaped and Probabilistically Shaped Bit-Loading DMT for Optical Interconnect System

IEEE Photonics Journal, 2020
We experimentally demonstrate the transmission performance of the bit-loading discrete multi-tone (DMT) signal in intensity modulation and direct detection (IM-DD) system with a transmission distance of 2km and a net data rate of 108-Gb/s by two ...
Junjie Ding, Jiao Zhang, Jianjun Yu
doaj   +1 more source

Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion

Advanced Science, EarlyView.
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang, Zixin Yang, Shan Wang, Weiwei Tan, Zhirui He, Qinyu Duan, Huanan Wang, Tao Chen, Shanshan Hu   +8 more
wiley   +1 more source

Ultrastrong TEMPO‐Oxidized Densified Bamboo via Interface Decoupling and Hierarchical Toughening

Advanced Science, EarlyView.
This study develops TEMPO‐oxidized densified bamboo that achieves ultrahigh strength and toughness by decoupling rigid hydrogen bonds into reversible van der Waals interactions. TEMPO oxidation reorganizes the cellulose hydrogen‐bonding network, facilitating energy dissipation via reversible interactions, thereby establishing a general strategy to ...
Ziyu Ba, Hongyun Luo, Jie Cui, Juan Guan, Zhaoliang Guo, Robert O. Ritchie   +5 more
wiley   +1 more source

Strategy Constancy Amidst Implementation Differences: Interaction-Intensive Versus Memory-Intensive Adaptations To Information Access In Decision-Making [PDF]

, 2004
Over the last two decades attempts to quantify decision-making have established that, under a wide range of conditions, people trade-off effectiveness for efficiency in the strategies they adopt.
Gray, Wayne, Myers, Christopher, Schoelles, Michael   +2 more
core   +2 more sources

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Treatment switches of disease-modifying therapies in people with multiple sclerosis: long-term experience from the German MS Registry

Therapeutic Advances in Neurological Disorders
Background: The spectrum of disease-modifying therapies (DMTs) for people with multiple sclerosis (PwMS) has expanded over years, but data on treatment strategies is largely lacking. DMT switches are common clinical practice.
Niklas Frahm, David Ellenberger, Alexander Stahmann, Firas Fneish, Daniel Lüftenegger, Hans C. Salmen, Ksenija Schirduan, Tom P. A. Schaak, Peter Flachenecker, Christoph Kleinschnitz, Friedemann Paul, Dagmar Krefting, Uwe K. Zettl, Melanie Peters, Clemens Warnke   +14 more
doaj   +1 more source

Modelling Dimethoate Removal by Fenton-Like Process Using Response Surface Methodology

Proceedings, 2018
The (RSM) is a useful method for optimizing analytical methods and it has been applied to evaluate independent variables in FPs. In this study, the removal of dimethoate (DMT) which is a commonly used pesticide and has a toxic effect on the environment ...
Berrak Erol Nalbur, Arzu Teksoy, Seval Kutlu Akal Solmaz, Hilal Safiye Azak   +3 more
doaj   +1 more source

Flexible Unusual Ternary‐Component Graded‐Modulus Dielectric Films with High‐Density Capacitive Energy Storage

Advanced Science, EarlyView.
Hierarchical PP–LSR107–BaTiO3 nanocomposite films are fabricated by one‐step extrusion and stretching for roll‐to‐roll manufacture, combining high energy storage and processing flexibility. LSR107 surrounds BaTiO3‐rich regions, locating amorphous PP, decreasing defects, and introducing deep traps that homogenize the electric field and suppress charge ...
Yi Gao, Xin‐Jie Wang, Lei Huang, Kun Xing, Baoquan Wan, Yan‐Hui Song, Jian‐Tao Wang, Li‐Juan Yin, Tong Liang, Yan Meng, Zunpeng Feng, Kai Huang, Ke Bi, Shao‐Long Zhong, Zhi‐Min Dang   +14 more
wiley   +1 more source