Results 1 to 10 of about 6,270,915 (209)
Defects Can Increase the Melting Temperature of DNA-Nanoparticle Assemblies [PDF]
J. Phys. Chem. B, 110 (2006) 16393-16396, 2007 DNA-gold nanoparticle assemblies have shown promise as an alternative technology to DNA microarrays for DNA detection and RNA profiling. Understanding the effect of DNA sequences on the melting temperature of the system is central to developing reliable detection technology.
Harris, Nolan C., Kiang, Ching-Hwa
arxiv +3 more sources
Self-assembling DNA-caged particles: nanoblocks for hierarchical self-assembly [PDF]
, 2008 DNA is an ideal candidate to organize matter on the nanoscale, primarily due to the specificity and complexity of DNA based interactions. Recent advances in this direction include the self-assembly of colloidal crystals using DNA grafted particles. In this article we theoretically study the self-assembly of DNA-caged particles. These nanoblocks combine
A. Y. Grosberg +6 more
arxiv +3 more sources
Capacity of DNA Data Embedding Under Substitution Mutations [PDF]
, 2011 A number of methods have been proposed over the last decade for encoding information using deoxyribonucleic acid (DNA), giving rise to the emerging area of DNA data embedding. Since a DNA sequence is conceptually equivalent to a sequence of quaternary symbols (bases), DNA data embedding (diversely called DNA watermarking or DNA steganography) can be ...
Balado, Félix
arxiv +5 more sources
Reentrant behavior of divalent counterion mediated DNA-DNA electrostatic interaction [PDF]
Phys. Rev. Lett. 105 (2010) 248101, 2009 The problem of DNA-DNA interaction mediated by divalent counterions is studied using computer simulation. Although divalent counterions cannot condense free DNA molecules in solution, we show that if DNA configurational entropy is restricted, divalent counterions can cause DNA reentrant condensation similar to that caused by tri- or tetra-valent ...
Le, Tung T, Lee, SeIl, Nguyen, Toan T
arxiv +3 more sources
Monte Carlo simulation of melting transition on DNA nanocompartment [PDF]
, 2005 DNA nanocompartment is a typical DNA-based machine whose function is dependent of molecular collective effect. Fundamental properties of the device have been addressed via electrochemical analysis, fluorescent microscopy, and atomic force microscopy. Interesting and novel phenomena emerged during the switching of the device.
Bard A J +6 more
arxiv +4 more sources
mAbs, 2022 Rapid release of biopharmaceutical products enables a more efficient drug manufacturing process. Multi-attribute methods that target several product quality attributes (PQAs) at one time are an essential pillar of the rapid-release strategy.
Bingchuan Wei +25 more
doaj +1 more source
Microbiome, 2023 Background IL-22 is induced by aryl hydrocarbon receptor (AhR) signaling and plays a critical role in gastrointestinal barrier function through effects on antimicrobial protein production, mucus secretion, and epithelial cell differentiation and ...
Jordan S. Mar +11 more
doaj +1 more source
Optimized design parameters for CRISPR Cas9 and Cas12a homology-directed repair
Scientific Reports, 2021 CRISPR–Cas proteins are RNA-guided nucleases used to introduce double-stranded breaks (DSBs) at targeted genomic loci. DSBs are repaired by endogenous cellular pathways such as non-homologous end joining (NHEJ) and homology-directed repair (HDR ...
Mollie S. Schubert +7 more
doaj +1 more source
BMC Cancer, 2023 Background KRAS mutations occur frequently in advanced non-small cell lung cancer (aNSCLC); the G12C mutation is the most prevalent. Alterations in STK11 or KEAP1 commonly co-occur with KRAS mutations in aNSCLC.
Cristina Julian +7 more
doaj +1 more source
BMC Plant Biology, 2023 Background Plant genome information is fundamental to plant research and development. Along with the increase in the number of published plant genomes, there is a need for an efficient system to retrieve various kinds of genome-related information from ...
Hisako Ichihara +17 more
doaj +1 more source