Results 1 to 10 of about 7,795,985 (403)
DNA methylation and DNA methyltransferases [PDF]
Epigenetics & Chromatin, 2017 The prevailing views as to the form, function, and regulation of genomic methylation patterns have their origin many years in the past, at a time when the structure of the mammalian genome was only dimly perceived, when the number of protein-encoding ...
Bestor, Timothy H +3 more
core +10 more sources
Defects Can Increase the Melting Temperature of DNA-Nanoparticle Assemblies [PDF]
J. Phys. Chem. B, 110 (2006) 16393-16396, 2007 DNA-gold nanoparticle assemblies have shown promise as an alternative technology to DNA microarrays for DNA detection and RNA profiling. Understanding the effect of DNA sequences on the melting temperature of the system is central to developing reliable detection technology.
Harris, Nolan C., Kiang, Ching-Hwa
arxiv +3 more sources
Self-assembling DNA-caged particles: nanoblocks for hierarchical self-assembly [PDF]
, 2008 DNA is an ideal candidate to organize matter on the nanoscale, primarily due to the specificity and complexity of DNA based interactions. Recent advances in this direction include the self-assembly of colloidal crystals using DNA grafted particles. In this article we theoretically study the self-assembly of DNA-caged particles. These nanoblocks combine
A. Y. Grosberg +6 more
arxiv +3 more sources
Capacity of DNA Data Embedding Under Substitution Mutations [PDF]
, 2011 A number of methods have been proposed over the last decade for encoding information using deoxyribonucleic acid (DNA), giving rise to the emerging area of DNA data embedding. Since a DNA sequence is conceptually equivalent to a sequence of quaternary symbols (bases), DNA data embedding (diversely called DNA watermarking or DNA steganography) can be ...
Balado, Félix
arxiv +5 more sources
Monte Carlo simulation of melting transition on DNA nanocompartment [PDF]
, 2005 DNA nanocompartment is a typical DNA-based machine whose function is dependent of molecular collective effect. Fundamental properties of the device have been addressed via electrochemical analysis, fluorescent microscopy, and atomic force microscopy. Interesting and novel phenomena emerged during the switching of the device.
Bard A J +6 more
arxiv +4 more sources
mAbs, 2022 Rapid release of biopharmaceutical products enables a more efficient drug manufacturing process. Multi-attribute methods that target several product quality attributes (PQAs) at one time are an essential pillar of the rapid-release strategy.
Bingchuan Wei +25 more
doaj +1 more source
Proceedings of the National Academy of Sciences, 1998 A DNA structure is described that can cleave single-stranded DNA oligonucleotides in the presence of ionic copper. This “deoxyribozyme” can self-cleave or can operate as a bimolecular complex that simultaneously makes use of duplex and triplex interactions to bind and cleave separate DNA substrates.
Shameelah R. Balkhi +2 more
openaire +3 more sources
Nature Reviews Methods Primers, 2021 Biological materials are self-assembled with near-atomic precision in living cells, whereas synthetic 3D structures generally lack such precision and controllability. Recently, DNA nanotechnology, especially DNA origami technology, has been useful in the bottom-up fabrication of well-defined nanostructures ranging from tens of nanometres to sub ...
Swarup Dey +11 more
openaire +4 more sources
Phosphorylating DNA with DNA [PDF]
Proceedings of the National Academy of Sciences, 1999 Nearly 50 individual DNAs with polynucleotide kinase-like activity were isolated from a random-sequence pool by using in vitro selection. Each self-phosphorylating deoxyribozyme makes use of one or more of the eight standard NTPs or dNTPs as a source of activated phosphate.
Yingfu Li, Ronald R. Breaker
openaire +3 more sources
The Need to Unravel Arsenolipid Transformations in Humans [PDF]
, 2022 The main source of arsenic exposure to humans worldwide is the diet, in particular, drinking water, rice, and seafood. Although arsenic is often considered toxic, it can exist in food as more than 300 chemical species with different toxicities.
Chávez-Capilla, Teresa
core +1 more source