Results 111 to 120 of about 31,432 (120)

DNA replication and daughter cell buddingare not tightly linked in the protozoan parasite

Microbes and Infection, 2001
In the protozoan parasite Toxoplasma gondii, cell division occurs by an unusual internal budding process whereby two daughter cells develop within and eventually subsume the mother cell. We have examined this process using inhibitors targeted at specific events in the cell cycle.
Michael K. Shaw, Lewis G. Tilney, David S. Roos   +2 more
openaire   +3 more sources

Experimental results on cell volume, growth rate, and macronuclear DNA variation in a ciliated protozoan

Journal of Experimental Zoology, 1987
AbstractSome species of ciliated protozoans vary their body volume when fed on preys of different sizes. This peculiarity has offered us the opportunity to examine the relationship between changes in cell volume, amount of macronuclear DNA (maDNA), and cell division rates in subclones derived from a single clone of the ciliate Blepharisma japonicum ...
SANTANGELO, GIOVANNI, Barone E.
openaire   +3 more sources

Vitamin E Scaffolds of pH-Responsive Lipid Nanoparticles as DNA Vaccines in Cancer and Protozoan Infection

Molecular Pharmaceutics, 2020
DNA vaccinations are promising strategies for treating diseases that require cellular immunity (i.e., cancer and protozoan infection). Here, we report on the use of a liposomal nanocarrier (lipid nanoparticles (LNPs)) composed of an SS-cleavable and pH-activated lipidlike material (ssPalm) as an in vivo DNA vaccine.
Mio Maeta, Naoya Miura, Hiroki Tanaka, Takashi Nakamura, Ryo Kawanishi, Yoshifumi Nishikawa, Kenichi Asano, Masato Tanaka, Shinya Tamagawa, Yuta Nakai, Kota Tange, Hiroki Yoshioka, Hideyoshi Harashima, Hidetaka Akita   +13 more
openaire   +3 more sources

Regulation of DNA replication proteins in parasitic protozoans: possible role of CDK-like kinases

Current Genetics, 2016
Regulatory roles of CDKs in fundamental processes including cell cycle progression and transcription are well conserved in metazoans. This family of proteins has undergone significant evolutionary divergence and specialization. Several CDK-like kinases have been identified and characterized in parasitic protozoans.
Abhijit S. Deshmukh, Meetu Agarwal, Suman Kumar Dhar   +2 more
openaire   +3 more sources

Sequence of the parasitic protozoan, Cryptosporidium parvum, putative protein disulfide isomerase-encoding DNA

Gene, 1996
A composite 1876-bp DNA encoding a putative protein disulfide isomerase (PDI) has been constructed from clones isolated from Cryptosporidium parvum (C. parvum) genomic and cDNA libraries and the nucleotide sequence determined. As predicted from the open reading frame (ORF), the protein product has a predicted molecular size of 54 kDa and a high degree ...
Beth A. Montelone, Nikolai V. Khramtsov, Steve J. Upton, Dennis S. Blunt   +3 more
openaire   +3 more sources

Amplification and sequencing of genomic DNA fragments encoding cysteine proteases from protozoan parasites

Molecular and Biochemical Parasitology, 1990
Cysteine protease gene fragments from three protozoan parasites Trypanosoma cruzi, Trypanosoma brucei, and Entamoeba histolytica were amplified by the polymerase chain reaction (PCR) from genomic DNA using degenerate oligonucleotide primers. The primers used for the amplification were designed based upon amino acid sequences flanking the active site ...
James H. McKerrow, Ann E. Eakin, Charles S. Craik, Judy A. Sakanari, Jacques Bouvier   +4 more
openaire   +3 more sources

Effects of DNA damage induced by UV irradiation on gene expression in the protozoan parasite Entamoeba histolytica

Molecular and Biochemical Parasitology, 2009
Previously, we provided evidence for the role of E. histolytica RAD52 epistasis group genes and the EhRAD51 recombinase in DNA damage response. To identify other genes participating in DNA repair in this protozoan parasite, here we analyzed the transcriptional response to genetic damage induced by ultraviolet light (UV) using cDNA microarrays. We found
Nancy Guillén, Nancy Guillén, César López-Camarillo, Christian Weber, Laurence A. Marchat   +4 more
openaire   +3 more sources

Structure and Characterization of Extrachromosomal DNA of Killer Xenosomes, Intracellular Symbionts of a Marine Protozoan

1986
Xenosome is the term we have adopted to describe a group of infectious intracellular bacterial endosymbionts found in several strains of the marine ciliate Parauronema acutum. Whereas symbionts of each strain are capable of infecting homologous and heterologous protozoan stocks, xenosomes from only certain strains are capable of killing other marine ...
A. T. Soldo, A. T. Soldo, S. A. Brickson, S. A. Brickson, A. F. Freytag, A. F. Freytag   +5 more
openaire   +2 more sources

Nucleotide sequence organisation and analysis of the nuclear ribosomal DNA circle of the protozoan parasite Entamoeba histolytica

Molecular and Biochemical Parasitology, 1994
We have sequenced the extrachromsomal ribosomal DNA (rDNA) circle of the human protozoan parasite Entamoeba histolytica HM-1:IMSS and present here the complete sequence organisation of the 24.5-kb molecule. Each circle contains two 5.9-kb rDNA transcription units organised as inverted repeats.
Sudha Bhattacharya, Devinder Sehgal, Vivek Mittal, Srinivasan Ramachandran, Suman Kumar Dhar, Alok Bhattacharya   +5 more
openaire   +3 more sources

DNA microarray analysis of protozoan parasite gene expression: outcomes correlate with mechanisms of regulation

Trends in Parasitology, 2004
DNA microarray analysis has been successfully applied to most of the protozoan parasites that cause human disease, but has not made equal progress in all cases. The results for kinetoplastid parasites (Leishmania and Trypanosoma) are primarily at the stage of validation and new gene discovery.
openaire   +3 more sources