Results 11 to 20 of about 44,514 (187)
Melittin as a promising anti-protozoan peptide: current knowledge and future prospects
Protozoan diseases such as malaria, leishmaniasis, Chagas disease, and sleeping sickness still levy a heavy toll on human lives. Deplorably, only few classes of anti-protozoan drugs have thus far been developed. The problem is further compounded by their
Hamed Memariani, Mojtaba Memariani
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Entamoeba histolytica is responsible for amoebiasis in humans. Its atypical cell cycle events and unique stress defense mechanisms make it different from other protozoan parasites.
Pinaki Biswas +4 more
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Sequence specificity of DNA adenine methylase in the protozoan Tetrahymena thermophila [PDF]
The sequence specificity of the Tetrahymena DNA-adenine methylase was determined by nearest-neighbor analyses of in vivo and in vitro methylated DNA. In vivo all four common bases were found to the 5' side of N6-methyladenine, but only thymidine was 3'. Homologous DNA already methylated in vivo and heterologous Micrococcus luteus DNA were methylated in
S, Bromberg, K, Pratt, S, Hattman
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Simultaneous Extraction of DNA and RNA from Nuclease-Rich Pathogenic Protozoan Trichomonas vaginalis
Chun-Fen Chou, Jung-Hsiang Tai
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Sensing DNA methylation in the protozoan parasite Entamoeba histolytica [PDF]
Summary In the protozoan parasite Entamoeba histolytica , 5‐methylcytosine (m5C) was found predominantly in repetitive elements. Its formation is catalysed by Ehmeth, a DNA methyltransferase that belongs to the Dnmt2 subfamily.
Tal, Lavi +5 more
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Introduction of plasmid DNA into the trypanosomatid protozoan Crithidia fasciculata. [PDF]
Crithidia fasciculata cells were treated with a plasmid (pDK96) containing pBR322 sequences, a Leishmania tarentolae maxicircle autonomously replicating sequence, and the bacterial gene for aminoglycoside 3' phosphotransferase I inserted between the yeast alcohol dehydrogenase 1 promotor and terminator sequences.
D E, Hughes, L, Simpson
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Bacterial and protozoan agents can determine abortion and other reproductive disorders in domestic ruminants, but data regarding their occurrence in wild ruminants are scanty worldwide, including in Italy.
Valentina Virginia Ebani +8 more
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Telomeres of polytene chromosomes in a ciliated protozoan terminate in duplex DNA loops [PDF]
The end of a telomeric DNA sequence isolated from a polytene chromosome of a hypotrichous ciliate folds back and hybridizes with downstream telomeric sequence to form a t loop that is stable in the absence of protein and DNA cross-linking. The single-stranded, telomeric DNA sequence at the end of a macronuclear molecule does not form a t loop but ...
K G, Murti, D M, Prescott
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An unusually compact ribosomal DNA repeat in the protozoanGiardia lamblia [PDF]
The ribosomal RNA (rRNA) genes of the protozoan parasite Giardia lamblia have been analyzed with respect to size, composition and copy number. They are found to be remarkable in several respects. First, the rRNAs themselves are the smallest yet reported for any eukaryotic organism.
J C, Boothroyd +3 more
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DNA Vaccines against Protozoan Parasites: Advances and Challenges [PDF]
Over the past 15 years, DNA vaccines have gone from a scientific curiosity to one of the most dynamic research field and may offer new alternatives for the control of parasitic diseases such as leishmaniasis and Chagas disease. We review here some of the advances and challenges for the development of DNA vaccines against these diseases.
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