Results 31 to 40 of about 142,373 (137)
Stem Cell Research, 2014 The loss of genome integrity in adult stem cells results in accelerated tissue aging and is possibly cancerogenic. Adult stem cells in different tissues appear to react robustly to DNA damage.
Leyla Vahidi Ferdousi +7 more
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A recombinant DNA‐satellite associated with Pepper yellow leaf curl Indonesia virus in highland area
Indonesian Journal of Biotechnology, 2021 Yellow curl disease caused by begomovirus is a major threat for horticulture in Indonesia. Control mea‐ sures for the disease face several constraints, one of which is the association between begomovirus and DNA satellites which can affect the severity ...
Argawi Kandito +3 more
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Assessing the Epigenetic Status of Human Telomeres [PDF]
, 2019 The epigenetic modifications of human telomeres play a relevant role in telomere functions and cell proliferation. Therefore, their study is becoming an issue of major interest.
Vaquero Sedas, María Isabel +1 more
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A conserved function for pericentromeric satellite DNA
eLife, 2018 A universal and unquestioned characteristic of eukaryotic cells is that the genome is divided into multiple chromosomes and encapsulated in a single nucleus. However, the underlying mechanism to ensure such a configuration is unknown.
Madhav Jagannathan +2 more
doaj +1 more source
RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster. [PDF]
, 2019 Tandemly-repeated DNAs, or satellites, are enriched in heterochromatic regions of eukaryotic genomes and contribute to nuclear structure and function. Some satellites are transcribed, but we lack direct evidence that specific satellite RNAs are required ...
Allshire +44 more
core +2 more sources
Genetics and Molecular Biology, 2008 We characterized sequences of a novel SSS139 RsaI satellite DNA family in Drosophila gouveai and Drosophila seriema, two members of the Drosophila buzzatii cluster (D. repleta group).
Fernando F. Franco +2 more
doaj +1 more source
Repeats as global DNA methylation marker in bovine preimplantation embryos [PDF]
, 2017 DNA methylation undergoes dynamic changes and is a crucial part of the epigenetic regulation during mammalian early development. To determine the DNA methylation levels in bovine embryos, we applied a bisulfite sequencing based method aimed at repetitive
Li, Wenwen, Peelman, Luc, Van Soom, Ann
core +2 more sources
PLoS ONE, 2013 The performance of adult stem cells is crucial for tissue homeostasis but their regenerative capacity declines with age, leading to failure of multiple organs.
Wendy Cousin +7 more
doaj +1 more source
Structural basis for DNMT3A-mediated de novo DNA methylation. [PDF]
, 2018 DNA methylation by de novo DNA methyltransferases 3A (DNMT3A) and 3B (DNMT3B) at cytosines is essential for genome regulation and development. Dysregulation of this process is implicated in various diseases, notably cancer.
Chen, Dongliang +11 more
core +2 more sources
BiomoleculesSatellite DNA repeats are repetitive DNA sequences found in eukaryotic genomes, typically consisting of short DNA motifs repeated in tandem arrays. Despite the vast body of literature on satellite DNA repeats in other taxa, investigations specifically ...
Muhammad Majid +4 more
doaj +1 more source