Results 91 to 100 of about 11,463 (183)

Efficient Cleavage of pUC19 DNA by Tetraaminonaphthols

ChemistryOpen, Volume 14, Issue 2, February 2025.
Anion receptor 4 was shown previously to cleave phosphodiesters by nucleophilic substitution. It also nicks plasmid DNA to some extent. We have now replaced the guanidines by ethylene diamine side chains. By this modification, the resulting tetraamine 13 becomes an effective DNA cleaver (R=H).
Catharina Kost, Ute Scheffer, Elisabeth Kalden, Michael Wilhelm Göbel   +3 more
wiley   +1 more source

Histones and histone variant families in prokaryotes

Nature Communications
Histones are important chromatin-organizing proteins in eukaryotes and archaea. They form superhelical structures around which DNA is wrapped. Recent studies have shown that some archaea and bacteria contain alternative histones that exhibit different ...
Samuel Schwab, Yimin Hu, Bert van Erp, Marc K. M. Cajili, Marcus D. Hartmann, Birte Hernandez Alvarez, Vikram Alva, Aimee L. Boyle, Remus T. Dame   +8 more
doaj   +1 more source

DNA Topoisomerases maintain promoters in a state competent for transcriptional activation in Saccharomyces cerevisiae.

PLoS Genetics, 2012
To investigate the role of DNA topoisomerases in transcription, we have studied global gene expression in Saccharomyces cerevisiae cells deficient for topoisomerases I and II and performed single-gene analyses to support our findings.
Jakob Madsen Pedersen, Jacob Fredsoe, Morten Roedgaard, Lotte Andreasen, Kamilla Mundbjerg, Mogens Kruhøffer, Marie Brinch, Mikkel Heide Schierup, Lotte Bjergbaek, Anni Hangaard Andersen   +9 more
doaj   +1 more source

Salerno's model of DNA reanalysed: could solitons have biological significance?

, 2006
We investigate the sequence-dependent behaviour of localised excitations in a toy, nonlinear model of DNA base-pair opening originally proposed by Salerno. Specifically we ask whether ``breather'' solitons could play a role in the facilitated location of
A. Bolshoy, A. Jeltsch, A. Kanhere, A. Scipioni, B. Sclavi, B.A. Hesselbach, B.A. Moffat, C. Gabriel, C.H. Choi, C.J. Benham, C.J. Benham, C.S. Park, D. Endy, D. Imburgio, E. Giudice, E. Lennholm, F. Lankas, F. Zhang, G. Gaeta, G. Gaeta, G. Nardone, H. Kabata, H. Wang, I.J. Bigio, I.J. Molineux, J. D. Bashford, J. SantaLucia Jr., J. SantaLucia Jr., J.D. Bashford, J.J.-L. Ting, J.P. Dausse, K.S. Murakami, L.R. Garcia, L.V. Yakushevich, L.V. Yakushevich, L.V. Yakushevich, M. Barbi, M. Frank-Kamanetskii, M. Frank-Kamensteskii, M. Guthold, M. Guéron, M. Peyrard, M. Peyrard, M. Salerno, M. Salerno, M. Salerno, M.E. Mulligan, N. Bruant, O.G. Berg, O.M. Braun, O.V. Tsodikov, P.H. von Hippel, P.H. von Hippel, P.T. Singer, R.V. Polozov, S. Cuenda, S.K. Zavriev, S.P. Smeekins, S.T. Estrem, S.W. Englander, S.Y. Ponomarev, Y. Jiao   +61 more
core   +1 more source

Strand separation in negatively supercoiled DNA [PDF]

, 2018
.: We consider Benham's model for strand separation in negatively supercoiled circular DNA, and study denaturation as function of the linking difference density ...
Mazza, Christian
core  

Universal solvent quality crossover of the zero shear rate viscosity of semidilute DNA solutions

, 2013
The scaling behaviour of the zero shear rate viscosity of semidilute unentangled DNA solutions, in the double crossover regime driven by temperature and concentration, is mapped out by systematic experiments.
de Gennes P.-G., Doi M., Duc At Nguyen, Grosberg A. Y., J. Ravi Prakash, P. Sunthar, Rubinstein M., Sambrook J., Sharadwata Pan, Sibileva M. A., T. Sridhar, Yamakawa H.   +11 more
core   +2 more sources

Circular superhelical DNA [PDF]

Nature, 1977
J A, Subirana, L C, Puigjaner
openaire   +3 more sources

DNA denaturation bubbles: free-energy landscape and nucleation/closure rates

, 2015
The issue of the nucleation and slow closure mechanisms of non superhelical stress-induced denaturation bubbles in DNA is tackled using coarse-grained MetaDynamics and Brownian simulations.
Destainville, Nicolas, Manghi, Manoel, Sicard, François   +2 more
core   +1 more source

Premelting of superhelical DNA: an expression for superhelical energy [PDF]

FEBS Letters, 1981
Vologodskii, A.V., Frank-Kamenetskii, M.D.   +1 more
openaire   +2 more sources

Reconstruction of complexes of histone and superhelical nuclear dna

Journal of Cell Science, 1981
ABSTRACT When HeLa cells are lysed in solutions containing a non-ionic detergent and 2 M-NaCl, structures are released that retain many of the morphological features of nuclei. These nucleoids contain all the nuclear RNA and DNA but few of the proteins characteristic of chromatin. Their DNA is supercoiled and so intact.
Levin, J, Cook, P
openaire   +3 more sources