The size of the nucleosome [PDF]
, 2011 The structural origin of the size of the 11 nm nucleosomal disc is addressed. On the nanometer length-scale the organization of DNA as chromatin in the chromosomes involves a coiling of DNA around the histone core of the nucleosome.
A. Travers +3 more
core +2 more sources
Preferentially quantized linker DNA lengths in Saccharomyces cerevisiae.
PLoS Computational Biology, 2008 The exact lengths of linker DNAs connecting adjacent nucleosomes specify the intrinsic three-dimensional structures of eukaryotic chromatin fibers. Some studies suggest that linker DNA lengths preferentially occur at certain quantized values, differing ...
Ji-Ping Wang +5 more
doaj +1 more source
The main early and late promoters of Bacillus subtilis phage ø29 form unstable open complexes with sA-RNA polymerase that are stabilized by DNA supercoiling [PDF]
, 1993 Most Escherichia coli promoters studied so far form stable open complexes with σ70-RNA polymerase which have relatively long half-lives and, therefore, are resistant to a competitor challenge. A few exceptions are nevertheless known.
Rojo, Fernando +3 more
core +1 more source
Specific DNA-RNA Hybrid Recognition by TAL Effectors
Cell Reports, 2012 The transcription activator-like (TAL) effector targets specific host promoter through its central DNA-binding domain, which comprises multiple tandem repeats (TALE repeats).
Ping Yin +6 more
doaj +1 more source
Role of the Discriminator Sequence in the Supercoiling Sensitivity of Bacterial Promoters
mSystems, 2021 DNA supercoiling acts as a global transcriptional regulator that contributes to the rapid transcriptional response of bacteria to many environmental changes.
Raphaël Forquet +4 more
doaj +1 more source
Probing the (H3-H4)(2) histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling [PDF]
, 2009 The (H3-H4)2 histone tetramer forms the central core of nucleosomes and, as such, plays a prominent role in assembly, disassembly and positioning of nucleosomes.
Bowman, A. +4 more
core +5 more sources
Differential influence of DNA supercoiling on in vivo strength of promoters varying in structure and organisation in E. coli [PDF]
, 1994 DNA supercoiling is known to influence promoter activity in vitro and in vivo in a promoter-dependent manner in prokaryotes. In order to investigate how topology may influence promoter function, we have studied two kinds of promoter variants, (i) where ...
Jyothirmai, G., Mishra, Rakesh K.
core +7 more sources
Stress-induced duplex destabilization (SIDD) profiles for T7 bacteriophage promoters [PDF]
Компьютерные исследования и моделирование, 2018 The functioning of DNA regulatory regions rely primarily on their physicochemical and structural properties but not on nucleotide sequences, i.e. genetic text.
Mikhail Anatolievich Orlov +4 more
doaj +1 more source
An organometallic compound which exhibits a DNA topology-dependent one-stranded intercalation mode [PDF]
, 2016 Understanding how small molecules interact with DNA is essential since it underlies a multitude of pathological conditions and therapeutic interventions.
Adhireksan +16 more
core +2 more sources
Journal of Chemistry, Volume 2026, Issue 1, 2026.Four ergostanes—ergosta‐7,22,24(28)‐trien‐3β‐ol (1), ergosta‐7,24(28)‐dien‐3‐one (2), ergosta‐7,22,24(28)‐trien‐3‐one (3), and ergosta‐4,6,8(14),22‐tetraen‐3‐one (4)—and one cytochalasin, zygosporin D (5), were isolated from Xylaria longipes. Two compounds, 2 and 3, are novel but have a similar structure to Compound (1), except for the keto group at ...
Alice W. Njue +5 more
wiley +1 more source