Preferentially quantized linker DNA lengths in Saccharomyces cerevisiae.
PLoS Computational Biology, 2008 The exact lengths of linker DNAs connecting adjacent nucleosomes specify the intrinsic three-dimensional structures of eukaryotic chromatin fibers. Some studies suggest that linker DNA lengths preferentially occur at certain quantized values, differing ...
Ji-Ping Wang +5 more
doaj +1 more source
Mitochondrial DNA replication in sea urchin oocytes [PDF]
, 1974 Mitochondrial DNA (mtDNA) replicative intermediates from Strongylocentrotus purpuratus oocytes were isolated by ethidium bromide-CsCl density gradient centrifugation and examined by electron microscopy after formamide spreading.
Kasamatsu, Harumi +3 more
core +2 more sources
Specific DNA-RNA Hybrid Recognition by TAL Effectors
Cell Reports, 2012 The transcription activator-like (TAL) effector targets specific host promoter through its central DNA-binding domain, which comprises multiple tandem repeats (TALE repeats).
Ping Yin +6 more
doaj +1 more source
Role of the Discriminator Sequence in the Supercoiling Sensitivity of Bacterial Promoters
mSystems, 2021 DNA supercoiling acts as a global transcriptional regulator that contributes to the rapid transcriptional response of bacteria to many environmental changes.
Raphaël Forquet +4 more
doaj +1 more source
Differential influence of DNA supercoiling on in vivo strength of promoters varying in structure and organisation in E. coli [PDF]
, 1994 DNA supercoiling is known to influence promoter activity in vitro and in vivo in a promoter-dependent manner in prokaryotes. In order to investigate how topology may influence promoter function, we have studied two kinds of promoter variants, (i) where ...
Jyothirmai, G., Mishra, Rakesh K.
core +7 more sources
“Breaking up is hard to do”: the formation and resolution of sister chromatid intertwines [PDF]
, 2014 The absolute necessity to resolve every intertwine between the two strands of the DNA double helix provides a massive challenge to the cellular processes that duplicate and segregate chromosomes.
Bartkova +110 more
core +1 more source
Stress-induced duplex destabilization (SIDD) profiles for T7 bacteriophage promoters [PDF]
Компьютерные исследования и моделирование, 2018 The functioning of DNA regulatory regions rely primarily on their physicochemical and structural properties but not on nucleotide sequences, i.e. genetic text.
Mikhail Anatolievich Orlov +4 more
doaj +1 more source
Circadian rhythms of superhelical status of DNA in cyanobacteria [PDF]
Proceedings of the National Academy of Sciences, 2007 The cyanobacterium Synechococcus elongatus expresses robust circadian (daily) rhythms under the control of the KaiABC-based core clockwork. Unlike eukaryotic circadian systems characterized thus far, the cyanobacterial clockwork modulates gene expression patterns globally and specific clock gene promoters are not ...
Mark A, Woelfle +3 more
openaire +2 more sources
ChemBioChem, Volume 26, Issue 24, December 11, 2025.Mercury (Hg) is a possible risk factor for Alzheimer's disease, where neuronal death is related to amyloid brain plaques containing aggregated amyloid‐β (Aβ) peptides. We show that equimolar Hg(I) or Hg(II) ions inhibit normal Aβ aggregation. Hg(II) binds Aβ(1–40) with an apparent binding affinity 28 ± 8 μM.
Elina Berntsson +7 more
wiley +1 more source
An organometallic compound which exhibits a DNA topology-dependent one-stranded intercalation mode [PDF]
, 2016 Understanding how small molecules interact with DNA is essential since it underlies a multitude of pathological conditions and therapeutic interventions.
Adhireksan +16 more
core +2 more sources